Myriad Genetics bought the Intermountain Precision Genomics (IPG) lab. I am working with my team to transfer the clinical NGS testing and the lab from IPG to Myriad.

Developed automated DNA/RNA extraction process for use in clinical lab.Developed automated cfDNA extraction process using PerkinElmer chemagic 360 instruments for use in clinical lab.Developing manual Next-generation sequencing process to perform targeted sequencing of ctDNA from blood plasma for use in clinical lab.Develop improvements in clinical lab as needed.

Managed personnel and lab operations of the Heredigene: A Population Study project in which the lab processed and prepared 10,000 blood samples for microarray and whole genome sequencing.Managed personnel and lab operations for several research projects using various technologies, including 10X Genomics, TwinStrand Duplex Sequencing, Whole Genome Sequencing, Whole Exome Sequencing, and RNA-Seq.

Implemented manual whole genome sequencing process into Intermountain Precision Genomics' Translational Science Center lab workflow. Also, implemented whole exome sequencing and RNA-Seq.Implemented 10X Genomics Genome Solution workflow in our lab.Implemented whole genome and whole exome sequencing automation methods on Hamilton Star Automation Systems to improve throughput in the lab.Implemented other automated solutions to improve throughput in the lab.

Examine the role of Smyd5 in cardiac hypertrophy and failure using mouse model studies, proteomics studies, and in vitro assays.Techniques used: qRT-PCR, ChIP-PCR, mass spectrometry, Western blotting, Histone methyltransferase assays, immunocytochemistry, immunohistochemistry