Mihai Azimioara work email
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Mihai Azimioara personal email
Motivated and passionate medicinal chemist with over 25 years of experience in drug discovery. Recently changed careers in a field that I always wanted to try out: education. Thank you Cal Coast Academy for the opportunity to teach full time!
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Research ChemistObiter Research LlcChampaign, Il, Us -
Research ChemistObiter Research Llc Sep 2024 - PresentChampaign, Illinois, Us -
Senior Scientist1859 Inc Sep 2022 - Jan 2023San Diego, California, Us -
Principal ScientistAdarx Pharmaceuticals Inc. Jan 2022 - Sep 2022San Diego, Ca, Us -
Senior Staff Scientist1859 Inc Jun 2021 - Jan 2022San Diego, California, Us -
Senior ScientistFerring Pharmaceuticals Jan 2021 - May 2021St-Prex, Ch -
Director Of ChemistryPlexium Apr 2018 - May 2020San Diego, California, Us• Led the effort of discovering novel E3-ligases molecular glues and PROTACs for targeted protein degradation with applications in immuno-oncology. • Played a major role in setting up and directing the medicinal chemistry group and in coordinating the collaboration with CROs. This also involved all the setting up and moving to new laboratory.• Contributed to the development of the DELPhe® high-throughput discovery platform. -
Research Investigator IiiGnf Oct 2003 - Mar 2018San Diego, Ca, Us• Collaborated on a variety of early-discovery research programs (hit ID, selection and validation; hit-to-lead generation; lead optimization and selection) in metabolic diseases, oncology, immunology and cystic fibrosis.• Contributed to the development of a series of GPR119 agonists for the treatment of type 2 diabetes and of two different series of CFTR correctors for the treatment of cystic fibrosis.• As part of a multidisciplinary team, delivered over ten different lead series to preclinical development programs.• Mentored a number of junior chemists in analytical and synthetic chemistry.• Optimized key synthetic steps in high-priority projects in order to meet stringent deadlines for compound scale-up and SAR optimization. -
Research ScientistAmbit Biosciences Apr 2002 - Jun 2003• Developed synthetic methods for biologically-active molecules to be used in linking to a poly-(ethylene glycol) biotinylated polymer with applications for testing in phage-display reverse-screening assays.• Independently managed medicinal chemistry projects around a number of kinase-inhibitor leads generated from the phage-display platform.
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Research Associate, Research ScientistArena Pharmaceuticals Apr 2000 - Apr 2002San Diego, Ca, Us• Managed three G-protein-coupled receptor projects.• Trained and supervised three Research Associates in medicinal chemistry. -
Research AssociateTrl Nov 1998 - Mar 2000Wokingham, Berkshire, GbPerformed synthesis, purification and analysis of small-molecule integrin-assembly inhibitors for anti-inflammatory treatment. -
Research AssociateAriad Pharmaceuticals, Inc. Oct 1996 - Oct 1998Cambridge, Massachusetts, Us• Designed and synthesized a number of small-molecule, peptide and peptidomimetic selective inhibitors of the tyrosine kinase Src; these specific SH2-domain ligands were designed for the treatment of osteoporosis by inhibiting osteoclast activity.• Developed HPLC methods for gram-scale separation of diastereomers. -
Research AssociateBiogen Mar 1996 - Oct 1996Cambridge, Ma, Us• Synthesized a number of peptide derivatives for activity towards asthma treatment.• Performed NMR conformational analysis on compounds of interest that led to a new series of compounds.
Mihai Azimioara Skills
Mihai Azimioara Education Details
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CaltechOrganic Chemistry -
Harvard UniversityOrganic Chemistry
Frequently Asked Questions about Mihai Azimioara
What company does Mihai Azimioara work for?
Mihai Azimioara works for Obiter Research Llc
What is Mihai Azimioara's role at the current company?
Mihai Azimioara's current role is Research Chemist.
What is Mihai Azimioara's email address?
Mihai Azimioara's email address is ma****@****gnf.org
What schools did Mihai Azimioara attend?
Mihai Azimioara attended Caltech, Harvard University.
What are some of Mihai Azimioara's interests?
Mihai Azimioara has interest in Science, Education, Teaching And Tutoring In Math, History.
What skills is Mihai Azimioara known for?
Mihai Azimioara has skills like Organic Chemistry, Analytical Chemistry, Spectroscopy, Medicinal Chemistry, Organic Synthesis, Lead Optimization, Drug Discovery, Drug Design, Hplc, Nmr, History, Mathematics.
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