Functioned as head of in vivo pharmacology, responsible for developing, refining and leading strategy for in vivo modeling of a broad set of product concepts (viral and non-viral) to treat multiple indications. Responsible for providing strategic leadership to programs from early development through IND-enabling studies. Worked with several cross-functional teams (e.g. disease teams, CMC, tech. ops.) as well as external CROs. Set up a new relationship with a CRO and… Show more Functioned as head of in vivo pharmacology, responsible for developing, refining and leading strategy for in vivo modeling of a broad set of product concepts (viral and non-viral) to treat multiple indications. Responsible for providing strategic leadership to programs from early development through IND-enabling studies. Worked with several cross-functional teams (e.g. disease teams, CMC, tech. ops.) as well as external CROs. Set up a new relationship with a CRO and designed/performed/monitored Tune’s first non-human primate study. Extensively worked with Finance, Legal, Project Management, and the company senior leadership team across several topics including budget, scheduling, project priorities, de-risking, as well as establishing/implementing activities and relationships required for short- and long-term strategic plans. Show less

Managed/performed major projects demonstrating efficacy of human neural stem cells in amyotrophic lateral sclerosis. Designed and implemented preclinical programs to select potential therapeutic candidates and targets. Oversaw day-to-day lab operations and supervised personnel. Prepared grant applications, manuscripts, and presentations.

Performed in vivo and in vitro neuropharmacology/behavioral experiments to elucidate spinal mechanisms of muscle spasticity following spinal ischemic injury. Identified potential therapeutic targets and tested preclinical agents. Collaborated with pharma in development of potential therapies (small molecules and biologics).