Milton Cornwall-Brady Email & Phone Number

Formed microCT imaging core facility.Developed extensive set of scripts to automate complex analysis of microCT dataDeveloped analysis tools to characterize surface roughness of bone, quantify calcification and fat infiltration in muscles, and segment visceral adipose tissue.Created workflow to combine microCT data with fluorescence tomography dataEstablished Excel templates to perform statistical analysis of microCT resultsSupported ongoing efforts to characterize the… Show more Formed microCT imaging core facility.Developed extensive set of scripts to automate complex analysis of microCT dataDeveloped analysis tools to characterize surface roughness of bone, quantify calcification and fat infiltration in muscles, and segment visceral adipose tissue.Created workflow to combine microCT data with fluorescence tomography dataEstablished Excel templates to perform statistical analysis of microCT resultsSupported ongoing efforts to characterize the affects of various drug candidates in many animal models.Conducted bone morphometry to characterize osteoporosis, bone tumors, and other bone disease modelsAnalyzed volume, density and distribution of various white and brown adipose tissue depots in vivoInvestigated fibrosis/calcification of muscle in models such as muscular dystrophy, ALS, and cardiotoxin-induced muscle necrosis Developed techniques to quantify dense aortic lesions in atherosclerosis models Wrote project reports, summarize data, and communicate results both internally and to external parties. Show less

Planned and conducted in vivo experiments to characterize the efficacy of novel anabolic bone forming agent.Analyzed/ interpreted data from DEXA, pQCT, microCT, NMR, and blood analysis equipment.Automated analysis/visualization with Octave/ImageJ.Developed software to extract data from native files for additional analysis and visualizationAssisted in conducting studies in anti-angiogenesis and muscle/fat remodeling programs.Wrote project reports, summarized data and… Show more Planned and conducted in vivo experiments to characterize the efficacy of novel anabolic bone forming agent.Analyzed/ interpreted data from DEXA, pQCT, microCT, NMR, and blood analysis equipment.Automated analysis/visualization with Octave/ImageJ.Developed software to extract data from native files for additional analysis and visualizationAssisted in conducting studies in anti-angiogenesis and muscle/fat remodeling programs.Wrote project reports, summarized data and communicated results both internally and to external parties. Show less

Developed VB.Net application to convert Excel spreadsheets to web applications. Used dynamically generated ASP pages as user interface for intranet application.VB program redirects user input into Excel and returns calculated results to web browser.Automating the generation of these applications .

Served as pharmacology department representative to IS/IT steering committee and assisted in the deployment of ActivityBase LIMS system at Cambridge site. Developed ActivityBase protocols and associated Excel templates for analysis of biological data and incorporation of that data into an Oracle database.Developed Matlab scripts and stand-alone executables to analyze and visualize data generated in the pharmacology departmentPerformed in vitro assay to characterize local anesthetic… Show more Served as pharmacology department representative to IS/IT steering committee and assisted in the deployment of ActivityBase LIMS system at Cambridge site. Developed ActivityBase protocols and associated Excel templates for analysis of biological data and incorporation of that data into an Oracle database.Developed Matlab scripts and stand-alone executables to analyze and visualize data generated in the pharmacology departmentPerformed in vitro assay to characterize local anesthetic properties of compounds.Assembled apparatus and developed experimental protocol Performed compound extracellular recording from isolated guinea pig vagus nerveCharacterized activity of compounds on subtypes of afferent airway neurons.Performed microdissection to isolate trachea with intact innervationConducted single-unit recording from nodose and jugular ganglia in isolated trachea with intact vagal innervationValidated targets identified in vagus ganglia recordings with guinea pig in vivo cough model.Developed new cough model of allergic rhinitis to more accurately assay compound efficacyTested compounds dosed by routes of administration including nose-only aerosol, ip and po Show less

Wrote C and Matlab programs to performed biochip design simulations.Results guided laboratory testing of prototypes and supplied theoretical basis for preliminary patent filings.Developed biochip computer interface utilizing custom written LabVIEW programs.Allowed automated prototype design testing under computer control.

Collection and analysis of in vivo electrophysiological recordings from gerbil auditory nerve.Produced in vitro electrophysiological recordings of vertebrate photoreceptors.Investigation of the genetic basis of a novel photopigment in photoreceptors performed utilizing RT-PCR.

Education record

Ms, Physics

Bs, Physics