Mindy Simon Email and Phone Number

● Principal Investigator of a research group of up to 12-15 BS and MS students at a time● Production of microparticle beads using alginate and fibrin for applications in bioprinting and drug toxicity testing using lipid polymer hybrid nanoparticles (LPHNPs) ● Active collaboration with Bioprinting lab at Lawrence Livermore National Laboratory to develop novel bioink materials for bioprinting● Development of Python and Arduino-based controls for syringe pumps and temperature control● Attracted $60k of external funding support (DOE/LLNL), $58k of internal funding support (SJSU’s RSCA and URG programs), $15k in state funding (CSUPERB), and $14k in funding for direct student support● Technical advisor for 16 completed MS student projects, Research advisor to an additional 37 students for completed MS projects, and Senior Capstone Design Project groups● Taught and developed new courses, including Biotransport Phenomena, Medical and Biological Polymers, Biomaterials, Physiology for Engineers, Senior Design Project, Experimental Methods in Biomedical Engineering, Biomedical Microsystems, MS Project/Thesis Preparation Seminar, Microfluidics lab

Materials Engineering DivisionMicro & Nano Technology Section● Python-based automation of syringe pumps and valves for fluid flow in microfluidic systems● Design and validation of an integrated phase coalescence module for droplet microfluidic processes● Arduino-based automation of peristaltic pumps, and design of a fabrication procedure for an in-vitro blood-brain barrier organ-on-chip platform● Design, fabrication, and validation of a device to produce fibrin microbeads● 2 patents issued

http://web.stanford.edu/group/sjeffreylab/● Development of hardware platform for nanoliter droplet manipulation using Electrowetting-on-Dielectric (EWOD) technology, including an epi-fluorescent microscopy unit and temperature-controlled chamber● Development of programs using both proprietary and open-source software for integration of cell dispensing, fluid metering, fluid mixing, drug dilution, and cell staining on an EWOD-based hardware platform● Directed development of MATLAB-based image processing program (with GUI) for quantitation of live/dead cell staining● Design of Electrowetting-on-Dielectric (EWOD) microfluidic devices for dispensing of single cells

http://biomint.eng.uci.edu/Dissertation: Microfluidic Tools for Stem Cell Biology http://escholarship.org/uc/item/5fx1z5q3● Development of electrical impedance-based techniques for detection of nucleic acid amplification and proteins in picoliter droplets● Design and characterization of a microfluidic system for multiplexed genetic analysis in picoliter droplets, including Labview-based automation of pumps● Design, optimization and validation of devices to increase the yield of neural stem/progenitor cells sorted using dielectrophoresis for transplantation studies (Collaboration with Dr. Lisa Flanagan, Dept. of Neurology)● Design and implementation of a device with integrated electrodes for electrical stimulation and pacing of induced pluripotent stem cell (iPSC)-derived cardiomyocytes • Recipient of 3 fellowships totaling over $100k of support• 6 journal articles published, 10 conference papers published, 3 patents issued

Gas Chromatography-Mass Spectrometry (GC-MS) method development for biomarker detection and trace volatile compound detection in human exhaled breath samples. Development of methods for the detection of non-volatile components of human breath samples, including High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) and protein microarrays.

Construction and validation of a pilot-sized reactor for the manufacture of a Manganese Oxide catalyst.

Supervision of production of plastic blends. Mechanical testing of plastic blends incorporating thermostabilizers, including tensile tests, abrasion testing, and molecular weight determination by melt flow index.