Life Science Product Development Expert
Ming Tan Consulting
I provided microfluidic-based disposable cartridge product development services, incorporating engineering design, rapid prototyping, assay optimization and manufacturing scale-up. With my expertise in microfluidic device engineering, material science and chemistry, I rapidly designed and developed bio-assay based consumable cartridges, integrating engineering design with material compatibility and assay performance requirements. My clients included BD Biosciences, NASA Ames, Lawrence Livermore National Labs, BioNEMS, Genia, Wafergen, Wave 80 Biosciences, and Gel Company. Examples of projects completed: - Designed, prototyped and tested microfluidic cartridges for a nanopore-based sequencing system, improving pore yield three fold - Developed surface modification methods for plastic cartridges to allow uniform flow, and reduce non-specific adsorption - Established and optimized a qPCR microchip manufacturing process, increased yields by three fold and reduced cost per chip over five fold - Provided design, prototyping and evaluation of a whole blood, cell-counting point-of-care testing cartridge, collaborated with assay development and instrument design engineers to ensure completion of all project milestones on- schedule - Developed and optimized the reagent release and mixing mechanism for a diagnostic product line - Designed, prototyped and tested multiple micro-fluidic systems for growth study of cells, nematodes, and microalgae in space science applications