• Designed, executed and analyzed cell-based experiments for the characterization of in-process and final biosimilar products• Prepared and revised protocols, SOPs, technical reports and regulatory documents related to cell-based assays• Worked in cross-functional teams and oversaw a CMC project

• Identified and analyzed SNPs in the 3′ UTR of KRAS by sequencing DNA of lung and ovarian cancer patients to determine 1) associations with cancer risk in collaboration with team of scientists in bioinformatics, genetics and oncology and 2) effect on KRAS expression using tissue culture methods • Designed and led a project on investigating 3′ UTR-dependent regulation of KRAS oncogene by 1) examining usage and effect of alternative polyadenylation sites, and 2) determining regulatory regions within the 3′ UTR of KRAS that interact with microRNAs and RNA-binding proteins using molecular and cell-based assays

Investigated mechanism of action of selective proprietary compounds using high-throughput cell proliferation assays, cell cycle analysis and apoptosis analysis in mammalian cells

Studied DNA repair mechanisms by measuring mutation rates and determining kinds of mutations arise during MAT switching in S. cerevisiae