Mirko M. Email & Phone Number

Paris, Île-de-France, France

• Developing advanced animal-free models to investigate interactions between cancer-associated fibroblasts (CAFs), the extracellular matrix (ECM), and immune cells within the tumor microenvironment to understand their.
• Leveraging multi-color flow cytometry, RNA sequencing, proteomics and bioinformatics to analyze mechanisms driving therapy resistance and liver cancer progression
• Led cross-functional projects developing targeted cancer therapies, working closely with immunology and bioinformatics teams to translate findings into potential liver cancer therapies

Paris, Île-de-France, France

Padua, Veneto, Italy

• Conducted advanced research on the prostate cancer tumor microenvironment, focusing on the interactions between cancer cells, immune cells, and ECM components to understand mechanisms of immune evasion
• Utilized high-throughput flow cytometry and bioinformatics to identify key biomarkers associated with prostate cancer progression and immune response
• Developed and optimized 3D models to enhance prostate cancer research accuracy, aiming to minimize animal testing through innovative experimental approaches

Padova, Veneto, Italia

Roma, Italia

• Focused on breast cancer research, investigating the epithelial-mesenchymal transition (EMT) and the role of metabolic changes in inhibiting this process via microRNAs
• Developed and employed both in vitro and in vivo models to study breast cancer progression, aiming to uncover mechanisms that regulate EMT and cancer cell invasiveness
• Utilized confocal microscopy, flow cytometry, and bioinformatics to identify potential therapeutic targets, contributing valuable insights to breast cancer treatment strategies

Bellinzona, Canton Ticino, Svizzera

• Focused on prostate cancer research, exploring how microbiota influences tumor progression and therapy resistance
• Engineered a bacterial strain designed to counteract microbiota-driven therapy resistance, aiming to enhance treatment efficacy in prostate cancer
• Applied multi-color flow cytometry and molecular techniques to investigate microbial-cancer cell interactions, collaborating with cross-disciplinary teams on microbiome-targeted therapeutic strategies

Stoccolma, Svezia

• Investigated metabolic reprogramming in cancer progression, focusing on how metabolic switches influence metastatic formation in breast cancer
• Utilized zebrafish models to study the impact of metabolic changes on metastasis, providing insights into potential therapeutic targets
• Applied confocal microscopy and cellular assays to analyze tumor behavior, strengthening cross-institutional collaborations on cancer metastasis research

Roma, Italia

Phd, Morphogenesis And Tissue Engineering

PhD in Morphogenesis and Tissue Engineering with research in breast cancer and tumor metabolism

Master'S Degree, Genetic And Molecular Biology In Base And Biomedical Research

Bachelor'S Degree, Biological Sciences