Mitchell Beck Email & Phone Number

Coventry, Ri, Us

Thousand Oaks, Ca, Us

Thousand Oaks, Ca, Us

- Design new automation processes to improve the overall manufacturing of cGMP biologic's; - Assess change controls for Product Reintroduction's and implement the automation updates required to successfully manufacture products;- Execute work orders and change controls to modify code for manufacturing's DeltaV DCS (Distributed Control System);- Provide automation support to the upstream manufacturing team during day-to-day operations;- Participate as a member of the IS (Information Systems) safety team to improve the Personal Safety and Awareness program at the Rhode Island site.

San Ramon, California, Us

- Worked under a Consent Decree with strict cGMP regulations to improve the Harvest Capture and Clarification process (Microfiltration, Chromatography, Buffer Prep, Media Prep, Clean-in-Place Systems) for Perfusion Bioreactors;- Drafted and executed Commissioning Test Protocols (CTP) and Automation Site Acceptance Tests (SAT) for the Software (Physical and Recipe Layer) and Hardware (Panel Components) associated with the DeltaV Production system;- Walked-down and redlined electrical drawings and P&IDs;- Implemented suggestions and recommendations from Engineering, Manufacturing, Validation, Quality Assurance, and QUANTIC in order to improve protocols and comparable GMP documents.

North Kingstown, Ri, Us

- Lead test projects to troubleshoot the root causes of failures in process equipment;- Write technical reports and protocols for clients to provide them with relative detailed test results;- Calculated the valve flow coefficients (CV) for spring check valves of various sizes from experimental data;- Inspected a manufacturing facility’s WFI system for rouge, and performed preventative maintenance (PM);- Analyzed contamination issues with a lead manufacturer’s mag-drive agitator sealing apparatus, and determined possible solutions to the problem;- Evaluated filter integrity for tangential flow ultrafiltration membranes after exposure to varying transmembrane pressures, steaming rates, and rapid temperature changes.

North Kingstown, Ri, Us

- Executed various clean-in-place (CIP) and steam-in-place (SIP) processes for cGMP operations;- Studied the effects of biopharmaceutical processes on gaskets, diaphragm valves, and autoclave hoses;- Examined varying tightening torques on industry leading ASME BPE Gaskets and Tri-clamps;- Assembled process piping to safely transfer steam, chemicals, and other materials;- Developed project testing plans for various equipment and wrote standard operating procedures (SOPs) for how the experiments should be performed, and how the equipment should be operated;- Performed routine inspections to confirm the facility is running properly.

- Scaled up a process for the growth of a probiotic organism from lab scale to production;- Planned inoculum, media, sugar, and buffer preparation and their required components;- Performed material balances on the process;- Sized and selected upstream and downstream equipment (fermenter, centrifuge, dryer, granulator, holding tanks, pumps, heat exchangers, etc.);- Developed the process operating and sterilization schedule by creating a Gantt chart;- Priced the utility, labor, quality control, quality assurance, raw materials, and equipment;- Financially analyzed: transfer price of product, sensitivities, depreciation, DCF, IRR, and NPV.

- Created high temperature thin film sensors (thermocouples, strain gages) for jet engine applications; - Manufactured and tested sensors on various substrates capable of extreme conditions (Mullite, Alumina, Yttrium Stabilized Zirconium, Ceramic Matrix Composites); - Bonded platinum wires to thin films via laser welding, parallel gap welding, and heat treatments;- Trained students in lab safety and equipment use;- Imported PDAQ text files into Microsoft Excel and analyzed data graphically.