Mehar Cheema Email & Phone Number

Cambridge, Ma, Us

Cambridge, Massachusetts, United States

Cambridge, Massachusetts, United States

Cambridge, Massachusetts, United States

•Key scientific contributor to the development of a multiplexed liquid biopsy platform, optimizing nanosensor assays to detect protease signals from blood for initial proof of concept.•Managed multiple external consultants and CROs to adapt Glympse’s technology for various delivery methods and deliver product analytics to inform on development.•Led the internal scaling of the sensor platform, working closely with Chemistry and Biology teams to advance method development for future applications.•Led the optimization of a 500+ peptide sensor library, refining assay parameters for Glympse’s nanosensor platform.•Managed a $1M+ external collaboration for LC-MS analysis, working with lead scientists to develop and validate multiplex sensor formulations.•Led cross-functional efforts as a project manager for new clinical indications, interfacing with the Strategy team to align scientific developments with business objectives.•Co-authored pending patents on key nanosensor platform innovations.

Cambridge, Massachusetts, United States

•Developed and characterized in vitro substrate cleavage profiles for a 16-plex protease diagnostic nanosensor panel.•Established three analytical methods for analyzing protease-based cleavage using plate-based screening, size exclusion chromatography and mass spectrometry.•Innovated new delivery systems, including inhalable and injectable formats for nanosensor detection, expanding the platform’s diagnostic potential across various indications•Generated valuable intellectual property through peptide substrate and sensor design to optimize protease cleavage profiles

Buffalo/Niagara, New York Area

Cell-Based Assay Technologies• Designed and developed novel 3D cell culture screening technologies for cancer cell line studies, adapted for use in various therapeutic applications, including T-cell co-culture and invasion assays.• Independently executed high-content screening, using confocal microscopy to monitor cellular morphology changes, and classified over 50 hits into preclinical development for large pharmaceutical clients.• Collaborated with the Chemistry and Mass Spectrometry teams to streamline cytotoxicity assays, achieving key client milestones in compound development.• Trained new scientists, developing comprehensive SOPs to ensure the smooth transition of ongoing client projects.

Biological Sciences Department

Graduate Teaching Assistant - BIOS 351• Taught aseptic and scientific techniques for working with pathological organisms in a lab setting.• Instructed students on microbiological cell culture, growth, and lab instrument usage.• Simplified complex scientific concepts, making them easy to understand for undergraduates.• Gained leadership experience by independently managing and leading lab sections.

Department Of Biopharmaceutical Sciences- Uic

Master's Thesis Research • Developed a microfluidic device for circulating tumor cell capture in cancer diagnostics via triplicate antibody-PAMAM dendrimer constructs.• Demonstrated the device's utility for pancreatic, ovarian, and renal cancer cell capture.• Quantified cell capture efficiency for monitoring cancer progression.

Master Of Science - Ms, Bioengineering And Biomedical Engineering

Activities and Societies: Alpha Eta Mu Beta, Bioengineering Graduate SocietySpecialization in Cell and Tissue Engineering

Bachelor Of Engineering - Be, Bioengineering And Biomedical Engineering

Activities and Societies: Society of Women Engineers, BMES

Regents With Honors Diploma