Currently seeking opportunities in laboratory or research settings.Synthetic organic chemist who has been out of the industry for ten years for personal reasons. Previously I have over 15 years of laboratory experience in the drug discovery industry. Over 7000 unique structures produced. Employed both solid-phase and solution-phase chemistries in the production of precursors, intermediates, and products. Multi-step reaction sequences resulted in yields ranging from a few milligrams (library products) up to 200g (starting materials or intermediates). Played active role in all phases of projects, including development, planning, running reactions, purifications, analysis, and reporting. Analytical development following SOPs and adhering to GSP and GLP regulations. All activities in strict compliance with waste-stream, and safety guidelines. Specialties: Solid- and solution-phase organic synthesis. Purification and analysis. Lab maintenance.
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Senior Associate ScientistCatalent Pharma Solutions (Formerly Cardinal Health) Feb 2008 - Feb 2009San Diego, CaUsed Empower to setup and run analytical tests of drug product. Studies completed of impurities, E/Z isomer, and placebo. Activities included sample and buffer preparation as well as instrument setup. Notebook and reporting. SOPs and safety guidelines. -
Research AssociateBiofocusdpi Jan 2006 - Oct 2006San Diego, CaProduced library of 400 compounds using parallel synthesis. Developed methods for solution phase techniques. Analyzed products using mass spectrometry and 1H-NMR. Synthesized starting materials on large scale (5g – 15g). Prepared samples for analytical evaluation and purification. Recorded findings and activities in notebook. Prepared reports. Searched databases.
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Research AssociateChemdiv, Inc. Apr 2004 - Apr 2005San Diego, CaSynthesized starting materials on multi-gram scale to be used in small molecule library production. Produced compound libraries requiring one or more steps in solution. Purified products using HPLC and column chromatography. Prepared larger-scale quantities of custom low molecular weight products using multi-step reactions. Ascertained quality of intermediates and products using LC/MS and 1H-NMR. -
Research Associate IiTriad Therapeutics, Inc. Dec 1999 - Jan 2003San Diego, CaDeveloped methods and produced focused chemical libraries in deep well format using solid phase organic synthesis. Analyzed products using mass spectroscopy and 1H-NMR. Synthesized intermediates on scales up to 750 g. Prepared samples for analytical and biological evaluation. Searched databases and ordered supplies. Setup original chemical inventory. -
Research AssociateAxiom Biotechnologies, Inc. Jul 1996 - Nov 1999San Diego, CaSynthesized peptides and other small organic chemical libraries. Prepared various precursors and products. Experienced with solid and solution phase parallel syntheses. Used HPLC, TLC, and mass spectrometry to analyze reaction progress and product quality. -
Lab HelperUc San Diego Department Of Pathology Feb 1994 - Jun 1996United StatesWash glassware, prepare solutions, clean incubators. Radioactive wipes tests, hazardous waste disposal. Order supplies, general lab upkeep.Science project: mammalian tissue culture, protein extraction, SDS-PAGE, western blot.
Michael Dalton Education Details
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Biochemistry/Chemistry -
General Education
Frequently Asked Questions about Michael Dalton
What is Michael Dalton's role at the current company?
Michael Dalton's current role is Experienced associate seeking laboratory roles..
What schools did Michael Dalton attend?
Michael Dalton attended University Of California, San Diego, San Diego Mesa College.
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Michael Dalton
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Michael Dalton
Partner At O'Leary, Shelton, Corrigan, Peterson, Dalton & Quillin, Llc (Serious Injury & Death Cases)St Louis, Mo3aol.com, yahoo.com, pagelaw.com1 (314) 3XXXXXXX
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