Michael Kroell Email & Phone Number

Cambridge, Massachusetts, United States

Emeryville, California, Us

Led the development of scalable, cost-effective cloud infrastructure to advance genomics and bioinformatics by driving automation, optimizing costs, and improving operational efficiency. Industry experience allows me to align technical initiatives with strategic goals, foster collaboration across teams, empower innovation, and drive continuous improvement.•AI Development: Led the team to build an internal AI platform using ChatGPT, Claude, and Llama APIs via Azure and AWS Bedrock, ensuring compliance with company policies through meta-prompts and content filtering.•Messaging Infrastructure: Designed and implemented a centralized messaging bus with AWS EventBridge across multiple AWS accounts, improving system communication.•Automation & Integration: Automated and integrated laboratory instrument data and HPC workflows, eliminating manual data handling and improving efficiency.•Collaboration Platform: Led the integration of Benchling ELM and HPC workflows into a new in-house app, centralizing metadata and results.•Regulatory Compliance: Streamlined GxP validation by optimizing IQ/OQ/PQ steps and codifying tests, cutting validation time for AWS reusable modules.•Change Management: Reduced change management overhead by implementing Jira, Bitbucket, and Jenkins for evidence tracking and change chains.•Process Auditing: Guided a team to audit and streamline development processes, reducing feedback loops and accelerating cycles.•Mentorship: Provided technical leadership and mentorship to IT Operations, fostering a culture of innovation and continuous improvement.

Emeryville, California, Us

I led the design and implementation of scalable, cost-effective cloud infrastructure ready for rapid scale. I focus on creating secure, efficient environments that enable breakthroughs in genomics and bioinformatics. I work closely with leadership teams to ensure alignment between technical initiatives and the company's strategic goals.•Strategic Leadership: Member of the Extended Leadership and Boston Site Leadership Teams, contributing to company-wide operational and growth strategies.•Infrastructure Management: Managed office relocations and lab build-outs, ensuring seamless transitions with minimal disruption by coordinating vendors and department heads.•Bioinformatics Enablement: Deployed Seqera Nextflow Tower to improve HPC pipeline monitoring, reduce feedback cycles, and enable bench scientists to run pipelines autonomously.•Cloud Cost Optimization: Migrated from Tableau to AWS QuickSight, reducing overhead and costs, while leading an AWS Immersion Day for team adoption and training.•Data Transfer Streamlining: Designed and implemented AWS Transfer Family to simplify CRO data transfers to S3, optimizing internal data workflows.•Security & Network Enhancements: Implemented SASE with Palo Alto Prisma Access to improve security across the network infrastructure.•Budget Management: Reduced IT budget by 10% by consolidating software solutions with similar functionalities.•Technical Leadership & Mentorship: Provided mentorship to IT Operations, fostering a culture of innovation and continuous improvement.

Emeryville, California, Us

I specialize in architecting scalable, cost-effective cloud solutions. I lead cross-functional teams, focusing on cloud cost optimization, automation, and improving operational efficiency using AWS. Passionate about advancing healthcare through cloud technology, I provide technical leadership while ensuring secure, high-performance infrastructure. My expertise spans cloud engineering, IT operations, and fostering scientific collaboration.•Cost Optimization: Reduced cloud costs by 70% using AWS spot instances, native services, serverless tech, and data hygiene practices.•Automation: Led AWS-driven processes, cutting patient sample turnaround time by 2 days.•Genomics Workflow: Implemented AWS Batch with Nextflow for FDA-validated genomics workflows, improving speed and reliability.•HPC Deployment: Deployed AWS pCluster (Slurm) with Apptainer/lmod/s3fs to optimize bioinformatics workflows.•Collaboration Platform: Designed Open On-Demand on AWS pCluster, centralizing tools like Jupyter, RStudio, and Geneious.•CI/CD: Built Jenkins infrastructure on AWS ECS Fargate & EFS, streamlining pipelines with reusable libraries.•Infrastructure as Code: Used AWS CloudFormation nested stacks for rapid infrastructure deployment.Containerization: Deployed Docker for bioinformatics tools, ensuring consistent deployment across environments.•Monitoring: Integrated Datadog for cloud monitoring and PagerDuty for incident management.•Security: Designed AWS VPC & account structures, enhancing security with AWS Organizations, SCPs, and AWS Config.•Networking: Optimized networking with AWS Transit Gateway and Transit VPC, reducing complexity and cost.•Identity Management: Implemented Okta SSO & MFA for secure user provisioning.•Leadership: Mentored IT Operations, fostering innovation and continuous improvement.

Boston, Massachusetts, Us

As a Cloud Architect in a rapidly scaling biotech company, I design, automate, and implement cloud infrastructure solutions that support business growth and operational efficiency. I lead the strategy for cloud adoption and integration, ensuring that cloud systems are resilient, cost-effective, and scalable. I collaborate with cross-functional teams to enable seamless transitions from design and testing to production, and ensure that cloud systems are optimized for high availability, performance, and compliance.•Designed and implemented AWS cloud solutions, optimizing performance, scalability, and cost-efficiency, including cloud-native application redesigns leveraging microservices architectures and DevOps pipelines.•Led the migration of large-scale genomic HPC grids from on-prem to AWS, leveraging EFS and Avere storage systems to ensure optimal I/O performance and long-term data retention while minimizing costs.•Built and maintained a global multi-site network with AWS Direct Connect, VPC Peering, and VPNs, ensuring redundant, high-availability connections between physical sites across multiple countries.•Drove automation of cloud-based systems for self-healing and failover capabilities, ensuring business continuity in case of failure.•Spearheaded cloud migration projects, significantly improving the performance and scalability of critical applications through automation and cloud-native service adoption.•Managed global infrastructure, including cloud network configurations, ensuring optimal performance with dynamic routing (OSPF, BGP, BFD) for fast convergence during failure scenarios.•Led efforts to ensure security and regulatory compliance in cloud environments, supporting business needs while meeting industry standards.These efforts have significantly enhanced operational efficiency, reduced costs, and improved the scalability of systems in support of the company’s aggressive growth in the biotech industry.

Boston, Massachusetts, Us

Led the design, configuration, and maintenance of scalable IT systems and infrastructure, ensuring reliability and compliance. I focused on driving technical innovation, mentoring teams, and delivering cross-functional projects aligned with business objectives.• Cloud & Automation: Designed AWS VPCs and account structures for cost optimization and security. Automated code deployments with Jenkins and CodeDeploy, facilitating smooth migrations to AWS. Used CloudFormation to implement infrastructure as code for VPCs and ECS clusters.• Containerization: Pioneered Docker adoption, standardizing deployments and training development teams.• Data Center Networks: Built FDA-compliant networks with Cisco Nexus switches, Palo Alto firewalls, and F5 load balancers. Migrated static routing to OSPF with BFD for redundancy.• Enterprise Applications: Transitioned users to Office 365 via a hybrid Exchange environment and automated Office 2016 deployments. Deployed VMware Horizon View with App Volumes, UEM, and a unified parent image.• Security & Compliance: Implemented Okta SSO and MFA, streamlining SaaS integrations and user management. Designed a two-tier Microsoft PKI infrastructure for secure authentication.• Big Data & HPC: Deployed Isilon clusters for HPC, optimizing storage and data access.• Networking & Site Setup: Configured centralized network authentication via Microsoft NPS. Delivered end-to-end infrastructure for new sites, including servers, networking, and wireless.• Monitoring & Incident Management: Implemented SolarWinds for proactive monitoring and PagerDuty for incident management.• Leadership & Mentorship: Delivered high-impact projects on time and mentored engineers on architecture, deployment, and best practices.My expertise bridges technical innovation and operational excellence, enabling scalable and secure IT solutions for fast-paced biotech growth.

Bedford, Ma, Us

Managed critical IT infrastructure operations, ensuring the seamless design, implementation, and maintenance of data center projects from concept to completion. Partnering with cross-functional teams, I provided technical leadership, third-line user support, and mentorship for help desk engineers. My role encompassed developing and maintaining comprehensive technical documentation, proactively researching emerging technologies, and aligning solutions with organizational goals to drive business continuity and innovation.• Data Center Modernization: Upgraded the production ESX 4.0 cluster on an IBM blade chassis to ESXi 5.1, eliminating single points of failure, implementing physical network load balancing, and leveraging DvSwitches, Network I/O Control, HA, and DRS. Standardized configurations using Host Profiles to ensure consistency across all blades.• Exchange Server Optimization: Decommissioned legacy Exchange 2007 servers in a hybrid 2007/2010 environment, integrating F5 load balancers to enhance service redundancy and reliability.• Network Reliability: Consolidated multiple older DHCP servers into a 2012 DHCP Cluster with failover capabilities. Enabled Name Protection in DNS to safeguard critical production server records.• Access Control & Monitoring: Centralized authentication for network devices using RADIUS, configured SQL-based logging for reporting, and enhanced network visibility with SolarWinds NPM, NTA, ASM, and Storage Profiler to optimize performance and enable automated self-healing.• Redundancy Planning: Identified and resolved single points of failure within the network, implementing solutions to ensure uninterrupted service availability.This hands-on experience and a proactive approach to innovation reflect my dedication to optimizing IT operations and delivering scalable, secure solutions that align with organizational needs.

Oversaw critical IT infrastructure and drove initiatives to optimize performance, reliability, and scalability. My expertise encompasses data center operations, project management, technical leadership, and innovation to meet evolving business needs.• Data Center Operations: Lead day-to-day operations, ensuring optimal performance and availability of systems. Spearheaded design and implementation of projects from concept to completion while managing user expectations and delivering technical solutions.• Storage Management: Manage and monitor SAN and NAS arrays; provision LUNs to maintain high performance for VMs.• Virtualization: Administer production vSphere clusters, including monitoring, patching, and provisioning of hosts and virtual machines.• Backup and Disaster Recovery: Oversee enterprise-wide backup solutions using Symantec BackupExec. Develop and test disaster recovery plans to meet RPO and RTO objectives.Server Administration: Manage Microsoft server systems (Active Directory, Exchange, SQL, WSUS, VPN, DFS, and Terminal Server) and leverage Group Policy for standardization, issue resolution, and software deployment.• ERP and Application Support: Monitor and manage ERP systems and SQL databases. Utilize VMware ThinApp to deploy encapsulated applications.• Hardware and Software Procurement: Specify, quote, and purchase IT assets, ensuring alignment with operational requirements and budget.• IT Leadership: Provide mentorship to help desk engineers, develop technical documentation, and manage ticketing systems.• VOIP Systems: Administer Cisco CCME and CUE VOIP solutions to ensure seamless communication.By continuously researching emerging technologies and improving processes, I deliver innovative solutions that enhance operational efficiency and align with strategic goals.

Windsor, Connecticut, Us

• Provided technical guidance to field engineers and managed customer expectations for complex Windows projects.• Assisted in worldwide Microsoft Active Directory / Exchange implementation for a multinational company.• Led migration of customers to Microsoft Windows 2003 and Exchange 2003.

Bachelor Of Science - Bs, Information Technology

As, Computer Systems Engineering