Matthew M. Mannarino, Ph.D. Email & Phone Number

Boston, Ma, Us

Bedford, Ma, Us

Bedford, Ma, Us

• Leads activities for the development of complex technologies, products and processes• Project Leader for Integrity Implant System from Concept Phase through Design Transfer and Launch• Contributes as technical expert or leader in multi-disciplined project teams• Subject Matter Expert for Anika platform technologies in Osteoarthritis, Non-orthopedic, and Regenerative Medicine solutions• Responsible for resource planning and allocation, plans and manages expenses within budget• Manage engineering and technical personnel at the direction of the VP of R&D• Design & development of new products following ISO 13485, 21 CFR part 820, & 21 CFR 210/211

Billerica, Massachusetts, Us

• Direct the company Research strategy in collaboration with the CSO & Director of R&D• Led R&D project teams on exploratory research for development of class 2 & 3 medical devices• Manage engineering and technical personnel at the direction of the VP of R&D• Design & development of new products following ISO 13485, 21 CFR part 820, & 21 CFR 210/211• Drove new medical devices through design verification with consideration to risk management• Key member of development team that received FDA 510(k) clearance(s) for HydroPICC product line• Led process development tasks for a drug-eluting thromboresistant catheter combination device• Managed Intellectual Property strategy & drove pipeline innovation tasks for developing novel IP• Principal Investigator for submission of grant applications (NIH/NSF SBIR, MLSC, & KidneyX)• Authored multiple white papers, peer-reviewed publications, presentations, & conference posters

• Led R&D project teams on exploratory research for development of class 2 & 3 medical devices• Managed engineering and technical personnel at the direction of CEO and Director of Engineering• Design & development of new products or processes following ISO 13485 & FDA 21 CFR part 820• Drove new medical devices through verification and validation with consideration to risk management• Managed transfer of products from R&D/Engineering to Manufacturing after regulatory approval• Developed method to synthesize custom silicone-based polyurethane by 2-step bulk polymerization• Performed two-way fluid-structure interaction of patient specific vasculature from First in Human trials• Evaluated novel vascular graft prototypes and mechanism of action in pre-clinical rabbit and ovine animal models• Coordinated with IP counsel to draft & revise patent applications & management of invention disclosures• Generated necessary documentation to convey design intent– including design plans, drawings, protocols, & reports

Cambridge, Ma, Us

Member of Rutledge Group:• Research on the electrospinning of polymeric nanofibers and spray-assisted layer-by-layer deposition ofpolyelectrolytes for use as composite proton exchange membranes in direct methanol and hydrogen fuel cells• Mechanical and tribological characterization and analysis of thermally treated electrospun nanofiber mats• Modeling of the terminal diameter of electrospun jets from rheological, mechanical, and electrochemical data• Environmental Health & Safety (EHS) officer for Rutledge Laboratory (6/2009 - 1/2013)

Cambridge, Ma, Us

• Research on the characterization of Ti/Cu RF sputtering deposition and plasma-etching of substrates• Research on high-aspect ratio through-plane vias on MCM packaging including: fabrication, stress inductance,temperature dependence, thermal shocking, failure analysis, and characterization• Develop novel designs for various fixtures and components for production of MEMS and MCM products• Perform mechanical and thermal testing of materials for use in MCM modules as well as failure analysis• Research on plasma processing and surface modification of polyimide films for Master’s Thesis

Natick, Ma, Us

• Processing of monolayer and multilayer nanocomposite film formulations by extrusion and blown-film extrusion• Characterization of nanocomposite films for thermal, mechanical, and barrier properties• Performed dynamic mechanical analysis, differential thermal analysis, thermogravimetric analysis, x-raydiffraction, transmission electron microscopy, and scanning electron microscopy for film sample analysis

Waltham, Ma, Us

• Write & edit drawing mark-ups, standard operating procedures, bills of materials, etc. for medical devices• Operation of injection-molding machines for production of in-house plastic components for blood-gas analyzers• Troubleshoot and resolve tolerance/functionality problems of medical devices in production• CAD modeling of parts and assemblies for various components/fixtures for medical device production

Phd, Materials Science & Engineering (Polymer Science)

Bs/Ms, Plastics Engineering