Mo Jaber, Phd Email & Phone Number

Los Angeles, California, United States

• Implemented Continuous Improvements for the production of Chloroethoxyfos precursor by adding a phase transfer catalyst and increased concentration of raw material resulting in increased product yield, improved process efficiency, boosted throughput and enhanced sustainability – >$500k accomplished in savings in Q1 2024 ($0.7-1.5 million projected yearly savings depending on production size and campaign duration)• Delivered a solution to use cheaper raw material in the preparation of Aztec precursor with no implication on product quality – $500k accomplished in yearly savings• Developed in the lab an efficient continuous microencapsulation formulation process for Chloroethoxyfos or Index – potentially doubling the current batch process production rate with smaller equipment footprint

San Diego, California, United States

• Led a group that provided Genomatica support and technical assistance for the downstream toll and demo plant manufacturing of caprolactam, hexamethylene diamine, (R)-1,3-butanediol, and other products all made by biological processes from sustainable sources • Identified and tagged over a dozen of downstream impurities present in ppm levels generated directly and indirectly by the bio upstream process of nylon caprolactam – impurities were impactful on nylon quality upon polymerization even in low levels; impurity sources were identified and mitigation plans were offered• Acted as the company lead chemist• Mentored young chemical engineers and chemists in acquiring lab skills and provided guidance and oversight for conducting research and lab work

Commerce, Ca

Commerce, Ca

• Provided troubleshooting support to plant operations as the need arose and during campaign start ups• Optimized plant processes, e.g. >10% improved yield in the lab and >5% in the plant for Chloroethoxyfos precursor, >3% improved yield in the lab for Dictrophos…• Designed a novel process from the ground up for the production of Smartblock potato sprout growth inhibitor with 20% savings over the existing process – expected yearly sales $20-25 million• Delivered a solution to salvage the use of out of specification raw material used in the preparation of Aztec precursor – savings > $1 million• Provided a wide array of lab tested options for plant effluent treatment• Established a recovery method for an HCl stream otherwise laced with highly malodorous n-butyl mercaptan in a heavy producing HCl process without caustic neutralization – potential savings > $200,000/campaign

Mobile, Alabama Area

• Worked in a GMP compliant plant setting as a member of an R&D team providing support and technical knowledge, day to day duties included identification of areas for process improvement, in lab process simulation and data acquisition, and eventual data transfer and communication with plant operation • Optimized the key step in the production process by finding the most suitable temperature and time relationship, yield enhanced by 10% in the lab and >7% in the plant (>$7 million/year in savings)• Identified sources of process recycle solvent major detrimental impurities, determined their fate and negative interactions in the process, proposed mechanisms for their consumption and offered methods for mitigation (>$1.6 million/year in savings)• Conducted projects independently in the lab from inception and oversaw their transfer to the pilot plant• Interacted closely with chemical engineers

Brevards, North Carolina

Management experience:• Supervised a group of 5-6 research associates (B.S., M.S. and Ph.D. chemists) in an FTE setting for a custom organic synthesis account set up by a major pharmaceutical company• Assigned projects to individual chemists upon receipt from client• Delivered weekly group status reports to client• Communicated closely with upper management and client• Approved shipments of targets to client• Supervised facility up-keepResearch experience:• Handled multiprojects load• Planned and executed target syntheses in multisteps and on 5 to 500g order size

Chicago, Illinois

• Interacted with biologists and computational chemists in designing and executing the syntheses of candidate compounds for biological testing• Prepared in one and multi-step syntheses ureas and indoles for biological testing as inhibitors of multidrug transporters• Prepared in one and multi-step syntheses bactericidal acyl hydrazides and hydroxy amides as potentiators in treating gram positive infections• Synthesized a novel clofazamine analog in a convergent synthesis that comprised 12 steps• Derivatized chloramphenicol and fluconazole synthetically• Synthesized 3 linezolid analogs in more than 10 steps each• Generated over 1500 new compounds during the tenure• Interacted strongly with an academic consulting team assisting in the effort of developing target compounds

Lincoln, Nebraska

• Prepared advanced intermediates in the convergent asymmetric syntheses of antibiotic natural products tetronasin (28 steps) and A80577 (20 steps)• Developed a general novel approach to prepare optically active substituted oxazolidin-2-one heterocycles, useful as chiral auxiliaries• Conducted palladium catalysis study on the cycloisomerization of tetraenes: prepared nitrogen based heterocycles from acyclic amines• Synthesized optically active aminoalcohols by highly stereocontrolled method• Developed a novel stereoselective olefination reaction of carbonyl compounds• Solved structural characteristics using analytical techniques (NMR, IR, HPLC...)• Supervised and assisted undergraduate students in acquiring common lab skills

Post Doc, Organic Synthesis

Advisor Jim Takacs

Ph. D, Organic Chemistry

Advisor Russell Linderman

B. S, Chemistry