Mo Jaber, Phd Email & Phone Number

Los Angeles, California, United States

• Implemented Continuous Improvements for the production of Chloroethoxyfos precursor by adding a phase transfer catalyst and increased concentration of raw material resulting in increased product yield, improved process.
• Delivered a solution to use cheaper raw material in the preparation of Aztec precursor with no implication on product quality – $500k accomplished in yearly savings
• Developed in the lab an efficient continuous microencapsulation formulation process for Chloroethoxyfos or Index – potentially doubling the current batch process production rate with smaller equipment footprint

San Diego, California, United States

• Led a group that provided Genomatica support and technical assistance for the downstream toll and demo plant manufacturing of caprolactam, hexamethylene diamine, (R)-1,3-butanediol, and other products all made by.
• Identified and tagged over a dozen of downstream impurities present in ppm levels generated directly and indirectly by the bio upstream process of nylon caprolactam – impurities were impactful on nylon quality upon.
• Acted as the company lead chemist
• Mentored young chemical engineers and chemists in acquiring lab skills and provided guidance and oversight for conducting research and lab work

Commerce, CA

Commerce, CA

• Provided troubleshooting support to plant operations as the need arose and during campaign start ups
• Optimized plant processes, e.g. >10% improved yield in the lab and >5% in the plant for Chloroethoxyfos precursor, >3% improved yield in the lab for Dictrophos…
• Designed a novel process from the ground up for the production of Smartblock potato sprout growth inhibitor with 20% savings over the existing process – expected yearly sales $20-25 million
• Delivered a solution to salvage the use of out of specification raw material used in the preparation of Aztec precursor – savings > $1 million
• Provided a wide array of lab tested options for plant effluent treatment
• Established a recovery method for an HCl stream otherwise laced with highly malodorous n-butyl mercaptan in a heavy producing HCl process without caustic neutralization – potential savings > $200,000/campaign

Mobile, Alabama Area

• Worked in a GMP compliant plant setting as a member of an R&D team providing support and technical knowledge, day to day duties included identification of areas for process improvement, in lab process simulation and.
• Optimized the key step in the production process by finding the most suitable temperature and time relationship, yield enhanced by 10% in the lab and >7% in the plant (>$7 million/year in savings)
• Identified sources of process recycle solvent major detrimental impurities, determined their fate and negative interactions in the process, proposed mechanisms for their consumption and offered methods for mitigation.
• Conducted projects independently in the lab from inception and oversaw their transfer to the pilot plant
• Interacted closely with chemical engineers

Brevards, North Carolina

• Management experience:
• Supervised a group of 5-6 research associates (B.S., M.S. and Ph.D. chemists) in an FTE setting for a custom organic synthesis account set up by a major pharmaceutical company
• Assigned projects to individual chemists upon receipt from client
• Delivered weekly group status reports to client
• Communicated closely with upper management and client
• Approved shipments of targets to client

Chicago, Illinois

• Interacted with biologists and computational chemists in designing and executing the syntheses of candidate compounds for biological testing
• Prepared in one and multi-step syntheses ureas and indoles for biological testing as inhibitors of multidrug transporters
• Prepared in one and multi-step syntheses bactericidal acyl hydrazides and hydroxy amides as potentiators in treating gram positive infections
• Synthesized a novel clofazamine analog in a convergent synthesis that comprised 12 steps
• Derivatized chloramphenicol and fluconazole synthetically
• Synthesized 3 linezolid analogs in more than 10 steps each

Lincoln, Nebraska

• Prepared advanced intermediates in the convergent asymmetric syntheses of antibiotic natural products tetronasin (28 steps) and A80577 (20 steps)
• Developed a general novel approach to prepare optically active substituted oxazolidin-2-one heterocycles, useful as chiral auxiliaries
• Conducted palladium catalysis study on the cycloisomerization of tetraenes: prepared nitrogen based heterocycles from acyclic amines
• Synthesized optically active aminoalcohols by highly stereocontrolled method
• Developed a novel stereoselective olefination reaction of carbonyl compounds
• Solved structural characteristics using analytical techniques (NMR, IR, HPLC...)

Post Doc, Organic Synthesis

Advisor Jim Takacs

Ph. D, Organic Chemistry

Advisor Russell Linderman

B. S, Chemistry