Engineering : Optimizing and improving the enzymatic DNA synthesis – Assay characterization of reagent - Screening of different conditions - Improve performance criteria - Validation of the system – Analysis data, documenting and presenting to the teamRegulatory role : - Management of regulatory compliance - Analysis of Essential Health and Safety requirements (EHSR) - EHSR implementation - Risk management - CE mark and UKCA mark - Technical file

Third year engineering school internship. Topic : Development of enzyme-linked immunosorbent assay (ELISA) to evaluate the magnitude and durability of antibody avidity elicited by the bivalent and quadrivalent HPV vaccines This entails expressing HPV vaccine and non-vaccine genotype virus-like particles (VLP) in cells by transfection, purifying them by gradient centrifugation, and evaluating them by SDS-PAGE and electron microscopy. These VLP was then used in ELISAs to quantify the "avidity" of… Show more Third year engineering school internship. Topic : Development of enzyme-linked immunosorbent assay (ELISA) to evaluate the magnitude and durability of antibody avidity elicited by the bivalent and quadrivalent HPV vaccines This entails expressing HPV vaccine and non-vaccine genotype virus-like particles (VLP) in cells by transfection, purifying them by gradient centrifugation, and evaluating them by SDS-PAGE and electron microscopy. These VLP was then used in ELISAs to quantify the "avidity" of vaccine antibodies (Cervarix and Gardasil) after vaccination and after natural infection. Optimisation of reagent characteristics (chaotropic agent, concentration, incubation time..) Show less

Study the antibiotics resistance of Mycobacterium Avium Complex in order to suggest an alternative treatment - Epidemiology - Retrospective study to determine antibiotic resistance trends in Quebec - Bibliography to find alternative antibiotics- Alternative research to inefficient first and second lign treatment - Antibiograms (microdilution technics)- Molecular diagnosis of Mycobacteria - DNA sequencing or rRNA 16S gene