Moorthy T Email & Phone Number

Navi Mumbai, Maharashtra, India

• Focused on enhancing recombinant viral vectors through process development by transient transfection.• Designing experiments, refine, optimize trouble shoot bioreactor studies at vector development process.• Single cell cloning process and quality of cell banking preparation (MCB, WCB).• Optimization's of clarification studies. Good understanding of viral vectors and other gene therapyvectors.• Supporting to plasmid batches(Microbial Upstream).• Handling Bioreactors (5L &10L), Wave bag (2L,10L & 20L).• Provide R&D laboratory support across the Bioprocess Development department through collaborationwith other scientists.• Working within a research team to plan, organize and execute R&D biopharmaceutical research projects.Support the tech transfer, development and optimization of cell culture.• Processes (Adherent, microbial, mammalian) and upstream unit operations (scale-up train, productionbioreactors,primary clarification).• Write and follow an experimental protocol and technical report.• Demonstrated experience in cell culture techniques for adherent cultures and suspension culturesystems.

Bengaluru, Karnataka, India

• Planning & leading the shift activity with team members.• Worked as shift lead with 15 members in Bioreactor operations.• Function as a technical lead to execute analysis and report on biopharmaceutical process research anddevelopment projects in the large molecule projects.• Provide technical direction and technical oversight to research projects, under the guidance andsupport of the Senior Scientist/Team Lead.• Reviewing the batch BMR in eLN-LIMS.• Operate equipment and run processes in a clean room environment, in accordance with batch record,user manuals, design parameters, equipment qualification protocols and validation protocols and currentstandard GMP operating procedures.• Reviewing the batch protocols for process changes.• Implemented the cost reduction in unit operations.• Executing the procurement details for batch consumables.• Collaborate with other departments and represent Manufacturing in cross functional initiatives andmeetings.• Responsible for planning and execution of project.• Act as a senior presence in the lab and a mentor to junior team members.• Support the development and introduction of new techniques.• Methods and processes to improve business effectiveness as required.• Prepare and support the preparation of technical presentations and report writing.

Bangalore Urban, Karnataka, India

• Working as a team player with 15 members in Bioreactor operations.• Experienced in aseptic methods of media and feed preparation.• Planning, Micro scheduling and Distribution of the shift activities.• Planning and proposing the raw materials and consumables.• Identified the root cause analysis of leakage issues in Bioreactor connection assembly.• Responsible for online filling and reviewing of quality documents of Batch checklists, annexure andlogbooks.• Trained & signed off on Performance Measures (PMs) relating to CIP, SIP, basic tank & instrumentoperations.• Handled stirred tank, Stainless steel and Single use bioreactors (10L,50L)• Operated of ATF2,ATF4 and ATF6.• Preparation of Quality documents such as Batch checklist, Annexure, etc.

Bengaluru, Karnataka, India

• Supporting the team for Media , Feeds and buffer preparation, filtration.• Material supplement for batch start to end.• Supported Inoculum suspension for scaling up.2 / 4• Analyzing the media, feed and compilation the results.• Analysis of the amino acid residual levels by reverse phase chromatography.• Analysis of protein-A by Affinity Chromatography.• Coordinated with maintenance team for periodic maintenance activities and Equipment / Instrumentstroubleshooting.• Assisted in Preparation of Quality documents such as Batch checklist, Annexure, etc.

• HPLC operation and troubleshooting.• Analysis (protein-A, Amino acid).• Buffer and standard Preparation• Sample management.• Result compilations.

M.Sc Biotechnology, 1St Class

B.Sc, Biotechnology, 1St Class