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Sandeep Dave is listed as Researcher | Texas A&M University | Molecular Cell Biology based in College Station, Texas, United States. AeroLeads shows a work email signal at tamu.edu and a matched LinkedIn profile for Sandeep Dave.
Sandeep Dave previously worked as Researcher at Texas A&M University and Researcher Neurodegenerative Diseases at Texas A&M University. Sandeep Dave holds Ph.D., Biochemistry from Institute Of Microbial Technology-Csir.
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Experience in molecular cell biology projects; most recent project focused on chromatin dynamics, nuclear proteins, and liquid-liquid phase separation.Utilizing advanced molecular biology techniques, including gene editing, proteomics, and super resolution microscopy, to gain deep insights into cell functioning and disease mechanisms.Executing research, analyzing data, and presenting findings.Research Publications:Find my complete list of publications and citations on my Google Scholar profile.https://scholar.google.com/citations?user=RwiudAsAAAAJ&hl=enResearch Areas:Molecular Biology | Cell BiologyGene Editing | Cell Culture | MicroscopyProteomics | Protein Phase SeparationAdvanced Data Analysis | Manuscript Preparation | Project Leadership
Listed skills include Cell Biology, Molecular Biology, Biochemistry, Life Sciences, and 17 others.
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College Station, Tx, Us
Exploring the behavior of nuclear organelles, with an emphasis on the HP1α protein and liquid-liquid phase separation (LLPS) under confinement. Developed stable cell line with retrovirus mediated gene silencing. A review article under communication. Trained graduate students.
College Station, Tx, Us
Project lead on the investigation of the mechanism of the FUS protein in ALS and FTD diseases: Biophysical characterization of the disease mutant. (Also contributed collaborative projects related to nuclear pore proteins).− Developed SiMRoD technique to study the FUS protein liquid to solid transition in mutant disease states of ALS and FTD.− Utilized an extraordinarily low frequency blinking dye to perform super resolution microscopy for FUS condensates structure.− Designed a molecular delivery system for tagged gene expression of the nuclear protein Nup98 by AAVS safe harbor stable gene integration in the human cell lines.− Trained and mentored interns.Molecular Cell Biology, Gene Expression and Regulation, Gene Editing, Protein Phase Separation, Protein Stability, Protein Folding, Protein Transport, Membrane-less Organelles, Intrinsically Disordered Proteins, Low Complexity Domain Protein, Protein Droplets, Single Molecule Microscopy, Amyotrophic Lateral Sclerosis (ALS), Fronto-temporal Dementia (FTD), Fused in Sarcoma (FUS Protein), Nuclear Import Proteins, Nuclear Pore Complex, Nuclear Transport, Nup62, Nup98, FG repeats, Particle Tracking, Stress Granules, Photo-activated Localization Microscopy (PALM or pPALM), Transportin.
Project lead on the investigation of kinesin-8 Kip3 mediated regulation of microtubule dynamics.− The novel finding on the cell division regulating protein kinesin 8 KIP3, new mechanism of action was presented first time.− Contributed to a collaborative project; development of a yeast model system to understand the mechanism of action of the anti-cancer drug Taxol.− Trained and mentored interns. Cell Division, Cancer, Mitosis, Microtubule Dynamics, Spindle, Tubulin, Kinesin, Motor Protein, Kinetochore, Taxol, Antimitotic drugs, Microtubule drugs and Mitotic Exit.
In
Project Lead: Regulation of Adipocyte function by all-trans-retinoic acid, pyridoxal-5-phosphate and therapeutic protease. (Demonstrated therapeutic role of Stem Bromelain (Phytoprotein) in adipocyte biology).− Designed and executed studies to explore the efficacy of the therapeutic protein stem bromelain in obesity and its mechanism in the mouse animal model system.− Contributed to a collaborative project (therapeutics and disease); biology and mechanism of hostpathogen interaction in infectious diseases and treatments; in another project the role of BAMLET in cancer.− Skilled various cell biology, protein, molecular biology, immunology techniques (more details in the Research Technical Skills section) helped in adapting any research field and quickly learn in depth experimentation protocol and research design development within short time and quick training. − Trained and mentored interns.Molecular Cell Biology, Gene Expression and Regulation, Gene Editing, Cell culture, transfection and transformation, transient and stable cell cloning, extraction and isolation of DNA and RNA, Polymerase Chain Reaction (PCR), Cloning; Site Directed Mutagenesis (SDM), PCR cloning, cDNA expression vector, genomic DNA promoter reporter assays, Light / Fluorescence Microscopy Cell Imaging, Super Resolution Microscopy.• Cell Line and Vector Development, Adeno-associated virus (AAV) gene editing, ELISA, FACS for the project Nuclear Receptors and Transcription Factors, Infectious Disease, Host-Pathogen Interaction -Mycobacterium tuberculosis (MTB).
In
https://www.csmcri.res.inGenomics and Metagenomics of extremophiles and marine microbes.Isolation, cloning and characterization of salt tolerant genes
https://www.glsbiotech.com/default.aspx
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Sandeep Dave is listed as Researcher | Texas A&M University | Molecular Cell Biology.
AeroLeads has found 1 work email signal at @tamu.edu for Sandeep Dave.
Sandeep Dave is based in College Station, Texas, United States.
Sandeep Dave has worked for Texas A&M University, The University Of Chicago And Iowa State University, Institute Of Microbial Technology, Central Salt & Marine Chemicals Research Institute, and Gujarat Life Sciences (P.) Ltd.
You can use AeroLeads to view verified contact signals for Sandeep Dave, including work email, phone, and LinkedIn data when available.
Sandeep Dave holds Ph.D., Biochemistry from Institute Of Microbial Technology-Csir.
Sandeep Dave is listed with skills including Cell Biology, Molecular Biology, Biochemistry, Life Sciences, Proteomics, Protein Expression, Protein Purification, and Polymerase Chain Reaction.
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