Marc Weinberg Email & Phone Number

I am a physician-scientist, board-certified psychiatrist, and faculty member in Psychiatry and Neurology at Massachusetts General Hospital and Harvard Medical School. As a clinician in the Mass General Hospital Neurology Department’s Memory Disorders Unit, I see new and established patients concerned about memory loss and neurodegenerative disease. I work occasional evenings and weekends at Newton Wellesley Hospital, Salem Hospital, and McLean Hospital in admissions, consult-liaison psychiatry, and inpatient for adult and geriatric psychiatry units. As a researcher, I am a Principal Investigator and Co-Investigator working within the Alzheimer’s Clinical and Translational Research Unit (ACTRU), led by Dr. Steven Arnold. I serve as a study clinician on numerous ongoing academic and industry-sponsored clinical studies commonly related to Alzheimer’s disease and related dementias, as well as other neurodegenerative diseases. My primary research interests involve the relationship of the immune system to neurodegenerative disease and the discovery of novel biomarkers (bodily fluid and cellular-based measures that help with diagnosis, prognosis, and prediction of response to treatment). My long-term interests are identifying new ways to reprogram the older adult immune system to protect against age-related neurological diseases. An example of my ongoing research is the study of an old vaccine (BCG) that prevents tuberculosis and how this vaccine might be repurposed as an Alzheimer’s disease prophylaxis or treatment. My research interests also span into older adult mental health. I am grateful to have received research support from the NIH, Alzheimer’s Association, Cure Alzheimer’s Fund, Massachusetts Life Sciences Center, IMPACT-AD, and Harvard Catalyst. I received my MD with Alpha Omega Alpha honors from the University of North Carolina (UNC) at Chapel Hill. Before medical school, I received his Ph.D. at the University of Colorado at Boulder in Behavior Neuroscience and Psychology, studying brain mechanisms of stress adaptation. This was followed by an NIH F32-supported postdoctoral fellowship working with the University of North Carolina Gene Therapy Center. There, I studied Adeno-Associated Virus (AAV) / host interactions and entry mechanisms, worked to develop new treatments for epilepsy, and generated novel viral vectors capable of cell-selective expression in the central nervous system. My full publication list is accessible at this link: bit.ly/35e3dFF