Sandeep Kumar Mulukala Narasimha Email & Phone Number

Talence, Fr

Pessac, Nouvelle-Aquitaine, France

- Conducting research to elucidate human membrane transporters' structural and functional attributes while developing and maintaining therapeutic area expertise in this field.- Utilize single-particle Cryo-Electron Microscopy (Cryo-EM) as the primary investigative method to analyze membrane transporter structures and their complexes.- Regularly employ mammalian and insect cells for protein expression and purification, essential for Cryo-EM analysis.- Utilize spectroscopy-based assays to assess the impact on transporter function.- Create specialized content, including research papers and educational materials, ensuring accuracy and clarity for diverse audiences.- Collaborate with interdisciplinary research teams globally to communicate research findings and align project goals.

Hyderabad, Telangana, India

- Continued expression, purification, and analysis of the biophysical characteristics of CD2AP protein, extending from Ph.D. research.- Authored a research article on the molecular evolution of slit-diaphragm proteins, condensing complex data into phylogenetic charts and simplistic diagrams for diverse audiences.

Prof. C.R Rao Road, Gachibowli, Hyderabad, Telangana, India

- Conducted comprehensive research on kidney podocyte proteins, including podocin, CD2AP, nephrin, and TRPC6, by expressing, purifying, and characterizing their oligomeric nature, contributing to understanding podocyte biology and kidney function.- Performed biophysical studies to elucidate the significance of podocin for kidney function and contribute to the comprehension of podocyte biology.- Utilized computational modeling and simulations to investigate podocyte proteins' evolutionary conservation patterns and structural features across species, providing valuable insights into kidney function and disease mechanisms.- Examined the effects of mutations on protein structure and function to uncover molecular mechanisms underlying kidney function and disease, offering valuable insights for therapeutic development.- Authored and co-authored four publications, managing the entire writing and submission process while coordinating with professors and students to produce conference materials and scientific journals.- Designed and standardized experimental protocols to facilitate efficient lab operations and contribute to ongoing research efforts in the field.

Hyderābād Area, India

- Conducted comprehensive analyses of crucial podocyte proteins essential for blood filtration to form urine in the kidney. Namely, CD2AP, podocin, TRPC6, and nephrin. - Generated 3D structural models and Investigated the impact of mutations on protein structure and function, providing valuable insights into the molecular mechanisms underlying kidney function and disease.- Was the first to identify intrinsically disordered regions in the slit-diaphragm proteins.

Hyderabad Area, India

- Addressed customer inquiries via chat, ensuring prompt and accurate resolution.- Maintained professionalism and adhered to company standards.- Recorded interactions accurately and collaborated with internal teams.- Met performance metrics for response time and customer satisfaction.

Cyber Gateway Towers, Hitech City, Hyderabad, Andhra Pradesh

- Contributed to developing in-game portals in the augmented reality mobile game Ingress, published by Niantic. - Actively collaborated with cross-functional teams, including game designers, to create interesting and safe in-game portals. - My main responsibility was to ensure that in-game portals were designed to enhance player experience without causing difficulties in real-world gameplay.

Hyderabad, Andhra Pradesh

- Building structural models for proteins lacking 3D experimental structure.-Performing targeted docking of natural compounds and designing new molecules based on common scaffold structures.-Conducting studies using 3D QSAR, CoMSIA, and CoMFA to evaluate the theoretical efficacy of natural compounds in disease alleviation.-Authored three publications based on research findings and was responsible for writing, editing, formatting, and finalizing drafts according to journal guidelines.

Ph.D

Master Of Science (Msc)

Pg Diploma

Bachelor Of Science (Bsc)

Intermediate (_+2) In Biology, Physics And Chemistry