Murilo Bueno, Phd Email & Phone Number

Houston, TX, US

Houston, Texas, United States

Athlone, County Roscommon, Ireland

• Coordinated the transfer of multiple analytical methods from a global pharmaceutical client focused on advanced therapy medicinal products. Methods included assays for Infectious Titer (TCID50), Genome ID, Viral Titer.
• Allocated resources for routine drug testing and method transfers
• Supervised 6 direct reports. Mentored and supported their career objectives in accordance with the company goals.
• Evaluated results and quality of cell-based potency assays for drug product release and stability
• Elaborated and reviewed non-conformance reports in compliance with GMP
• Reviewed method transfer plans and associated documents

Vilnius, Lithuania

• Coordinated research and development activities to support the portfolio of Molecular and Synthetic Biology Tools products (e.g. DNA and RNA modifying enzymes, cloning, e-gels, competent cells)
• Assembled a team of 5 scientists and managed their activities focused on product development and optimization
• Established communication with groups based in Germany and Israel to support the development and optimization of products
• Actively participated in processes of technology scouting
• Engaged in strategic planning and practical process improvement activities

Vilnius, Lithuania

• Planned, managed and supervised R&D projects focused on the production and analytical characterization of Biologicals (e.g. scFv antibodies, human hormones)
• Supervised a team of 5 scientists and managed their activities
• Prepared and presented project progress reports to clients and addressed their queries
• Elaborated project proposals requested by clients and generated scientific data reports

El Paso, Texas Area

• Provided training to 6 research teams on recombinant expression and purification of chemokines relevant to Acute Lymphoblastic Leukemia
• Efficiently administered 2 university laboratory courses and taught fundamental research principles to 60 undergraduate students
• Generated, analyzed and published scientific results on the effect of HIV-1 infectivity upon depletion of a human co-factor protein

County Galway, Ireland

• Designed and coordinated projects focused on the study of key proteins required for proper DNA damage repair
• Implemented cell, molecular and biochemical approaches (e.g. cell line development, gene cloning and mutation, fluorescence microscopy, etc.) to elucidate the role of a lysine demethylase (KDM2A) during the process of.
• Effectively analyzed scientific results and communicated findings via elaboration and publication of a research article and 2 poster presentations at international conferences
• Demonstrated leadership and productive time management by coordinating a research project in collaboration with laboratories located in Ireland and Canada
• Mentored and provided adequate technical training to 2 graduate students

Montreal, Canada

• Planned and conducted studies focused on cancer-related epigenetic changes due to protein post-translational modifications (Ubiquitination, SUMOylation and Methylation)
• Applied multiple techniques (e.g. Chromatin Immunoprecipitation-qPCR, RT-qPCR, Immunoblotting) to reveal the role played by SUMOylation in the process of modulating the recruitment of a lysine demethylase (KDM5B) to.
• Performed data analysis, elaborated and published an article and presented 2 posters at national and international conferences
• Elaborated and submitted research proposals to funding agencies which resulted in the award of 2 post-doctoral fellowships

El Paso, Texas

• Designed and performed multiple projects to study distinct cellular proteins during HIV-1 infection
• Implemented numerous methods (e.g. lentiviral production/transduction, cell-based assays, flow cytometry) to conduct projects that ultimately resulted in the publication of 4 articles and presentation of 8 posters at.
• Proposals supported by data generated in these published studies led to the approval of over US$1 million in grant funding
• Efficiently managed time by concomitantly working as a research and teaching assistant
• Provided competent teaching of 3 undergraduate courses offered to a total of 90 students

Instituto De Ciências Biomédicas, Sao Paulo, Brazil

• Conduction of an undergraduate scientific project aiming to detect changes in expression and activity of glutathione-S-transferase in the liver of rats upon drug treatment

Doctor Of Philosophy (Ph.D.), Pathobiology

Ciências Biológicas - Bacharelado, Ciências Biológicas