Murphy Keller Email & Phone Number

Kansas City, Mo, Us

Coralville, Iowa, United States

o Maintain compliance with CLIA regulations for high complexity testingo Perform Next Generation Sequencing for CDC’s PulseNeto Perform clinical and environmental testing by PCR methods under BSL2 and BSL3 conditions (EHEC, COVID-19, Mpox, Mumps, Norovirus, Legionella, HPV-VZV, Cryptosporidium and other organisms)o Perform clinical and environmental testing using combinations of culture, enzyme substrate, MALDI, and traditional… Show more o Maintain compliance with CLIA regulations for high complexity testingo Perform Next Generation Sequencing for CDC’s PulseNeto Perform clinical and environmental testing by PCR methods under BSL2 and BSL3 conditions (EHEC, COVID-19, Mpox, Mumps, Norovirus, Legionella, HPV-VZV, Cryptosporidium and other organisms)o Perform clinical and environmental testing using combinations of culture, enzyme substrate, MALDI, and traditional biochemical methods under BSL2 and BSL3 conditions (EHEC, Salmonella spp, Campylobacter spp., Vibrio spp., Aeromonas spp., and other organisms)o Perform rabies testing using the fluorescent antibody testo Perform clinical testing by Aptima TMA methods (COVID-19, CT/NG)o Perform media QC and tracking, manage laboratory inventory and orders Show less

Iowa City, Iowa Area

I completed my Master's of Science degree in the lab of Dr. Mary Wilson. I defended my thesis, "The Composition and Function of Extracellular Vesicles in Leishmaniasis," in August of 2020. I was initially a PhD candidate, but exited the program early and in good standing due to the COVID-19 pandemic in order to pursue a job opportunity at the State Hygienic Lab performing COVID testing. Leishmania spp. parasites cause the disease leishmaniasis, including Visceral leishmaniasis (VL)… Show more I completed my Master's of Science degree in the lab of Dr. Mary Wilson. I defended my thesis, "The Composition and Function of Extracellular Vesicles in Leishmaniasis," in August of 2020. I was initially a PhD candidate, but exited the program early and in good standing due to the COVID-19 pandemic in order to pursue a job opportunity at the State Hygienic Lab performing COVID testing. Leishmania spp. parasites cause the disease leishmaniasis, including Visceral leishmaniasis (VL), which is usually fatal in humans without treatment. There are an estimated 0.5 million new reported cases and 50,000 deaths caused by VL annually. Current treatments are associated with toxicity, and many are administered intravenously and thus cumbersome in endemic regions. There is emerging drug resistance, and the drugs frequently have costs higher than the average annual household income of afflicted individuals. Novel approaches to disease management, therefore, are needed.Like most cells, human cells infected by leishmaniasis release small packets of cellular information called exosomes. Exosomes play a role in cellular communication both under normal circumstances and during disease. We hypothesized that exosomes released from infected human cells play a role in the progression of disease. The data presented support this hypothesis and raise new questions as to how the exosomes do so. My thesis research provides evidence that infection by L. infantum alters the protein composition of exosomes released by human macrophages. Proteins that were found to be present at significantly different levels based on infection status included proteins associated with inflammation, viral uptake, lipid metabolism, and the regulation of chromatin.The link below is a brief description of my thesis research, which I presented at the Three Minute Thesis Competition Finalist Showcase at the University of Iowa in November of 2019. Show less

Iowa City, Iowa, United States

Assisted with two courses in the University of Iowa Microbiology Department.Nursing Microbiology Lab, Spring 2018: Presented lab opening lectures, answered student questions, and assisted with lab setup and activities for three lab sections weekly.Eukaryotic Pathogens and Human Disease Lecture, Spring 2020: Designed and presented lecture over Vector Competence, led review sessions, and answered student questions in class sessions twice weekly. Course transitioned to online… Show more Assisted with two courses in the University of Iowa Microbiology Department.Nursing Microbiology Lab, Spring 2018: Presented lab opening lectures, answered student questions, and assisted with lab setup and activities for three lab sections weekly.Eukaryotic Pathogens and Human Disease Lecture, Spring 2020: Designed and presented lecture over Vector Competence, led review sessions, and answered student questions in class sessions twice weekly. Course transitioned to online midway through semester due to COVID-19 pandemic. Led a sucessful transition to online learning with minimal disruption. Show less

Columbia, Missouri Area

Led two hour open tutoring sessions in Cell Biology or Genetics twice weekly, in addition to tutoring individuals or small groups (1-4 students) for one hour sessions weekly or biweekly in Latin I, Intro to Biology, Cell Biology, and Genetics.2016 recipient of the Bonnie Zelenak Excellence in Tutoring Award

Columbia, Missouri, United States

From June 2014 to May 2016, I worked in the McClellan Laboratory on a project titled Axonal Regeneration of RS Neurons in the Lamprey: Acute vs. Chronic Spinal Injury. I was involved in set up of experimental and control groups and I determined which of several procedures would be most effective for carrying out experiment. I was responsible for preparation, care, behavioral recordings, retrograde labeling and dissections of lampreys. I conducted data analysis of lamprey recovery based on RS… Show more From June 2014 to May 2016, I worked in the McClellan Laboratory on a project titled Axonal Regeneration of RS Neurons in the Lamprey: Acute vs. Chronic Spinal Injury. I was involved in set up of experimental and control groups and I determined which of several procedures would be most effective for carrying out experiment. I was responsible for preparation, care, behavioral recordings, retrograde labeling and dissections of lampreys. I conducted data analysis of lamprey recovery based on RS neurons exhibiting retrograde labeling.I received the Life Sciences Undergraduate Research Opportunity Program fellowship in summer 2014 and the Arts & Sciences Undergraduate Research Mentorship Program in summer 2015.I presented my project in July 2014 at University of Missouri, Columbia Summer Undergraduate Research and Creative Achievements Forum, and at the University of Missouri Undergraduate Research and Creative Achievements Forum in April 2016.I also served as Biology Lab Social Chair from June 2015-May 2016. I coordinated events for the lab, strengthening team relationships. Show less

Master Of Science - Ms, Microbiology And Immunology

Activities and Societies: Connecting Science to Society (founding member) I completed my Master's of Science degree in the lab of Dr. Mary.

Bachelor'S Of Science, Biology/Biological Sciences, General

Minor in English Honors Certificate Multicultural Certificate