Scientist
Warminster, Pennsylvania, United States
I was an active participant in a cross functional team that was designing, analyzing, and producing novel pan-coronavirus therapeutics in search for a clinical candidate. As a medicinal chemist, I aided in the development of the Arbutus patent portfolio, adding to the library of novel structures. I scoured the literature for biological data of multiple different scaffolds that could be used on our potential compounds as well as our own database of compounds that could be adapted to the desired… Show more I was an active participant in a cross functional team that was designing, analyzing, and producing novel pan-coronavirus therapeutics in search for a clinical candidate. As a medicinal chemist, I aided in the development of the Arbutus patent portfolio, adding to the library of novel structures. I scoured the literature for biological data of multiple different scaffolds that could be used on our potential compounds as well as our own database of compounds that could be adapted to the desired core structure. I conducted the analyses and documentation of all experiments and compounds produced, as well as prepared the data and protocols for patent publication. Along with my own syntheses, I also schemed separate compounds for our contract research organizations (CRO) to produce and assisted in troubleshooting any of the problems that were presented. I also assisted the process group of taking the accepted clinical candidate and performing the initial scale ups of the active pharmaceutical ingredients (APIs). Show less