Nalin Subasinghe Email & Phone Number

Skilled Medicinal Chemist with pharmaceutical industry experience at both a small biotechnology company and a large pharmaceutical company. Extensive experience in leading medicinal chemistry teams from lead optimization to preclinical development. Experience working in cardiovascular, inflammation and pulmonary disease, oncology, metabolic, and analgesics therapeutic areas. Broad experience in multiple drug targets, including kinase inhibitors, G-protein coupled receptor targets, protease inhibitors, and ion channel targetsExperience working with CROs and managing outsourcing efforts on multiple projectsExperienced project and people manager - coordinated the effort of 5-14 chemists in multiple lead optimization campaigns. Liaised with safety pharmacology, toxicology, chemical and pharmaceutical development, and drug metabolism and pharmacokinetics groups to compile the data package (monograph) necessary to nominate a lead compound for early clinical developmentDemonstrated strength in multi-tasking with overall responsibility for 4 projects (CXCR2, PDGF kinase, C1s, DPP1) and a support role on 2 others (tryptase, TPL-2) from 2003–2006. Active participation on 4 project teams from 2010–presentExcellent interpersonal, teamwork, and verbal/written communication skillsStrong publication record: 19 publications in peer-reviewed journals, more than 16 patents/pending patents, and more than 17 poster presentationsCompleted the Regulatory Affairs Professional Society (RAPS) Regulatory Affairs Certificate to gain a good understanding of the regulatory process, including IND, NDA, ANDA filing, overview of the CMC and other sections of dossiers, and the eCTD formatExpertise – drug discovery, synthetic chemistry, structure-based drug design (SBDD), parallel synthesis, pegylated drug conjugates

Listed skills include Drug Discovery, Medicinal Chemistry, Drug Design, Organic Synthesis, and 38 others.