Nana Ankrah Email & Phone Number

Cambridge, England, United Kingdom

- Responsible for the setup, development, validation, and implementation of the in vitro micronucleus (IVMN) assay for the drug discovery screening portfolio. - Analysed and interpreted biological data with a focus on genotoxicity providing actionable insights.- Integrated automation into assay development to streamline processes and improve assay design. - Managed stakeholder requests and deadlines, ensuring timely delivery of results.- Performed routine cell culture, cell… Show more - Responsible for the setup, development, validation, and implementation of the in vitro micronucleus (IVMN) assay for the drug discovery screening portfolio. - Analysed and interpreted biological data with a focus on genotoxicity providing actionable insights.- Integrated automation into assay development to streamline processes and improve assay design. - Managed stakeholder requests and deadlines, ensuring timely delivery of results.- Performed routine cell culture, cell harvesting, cytology slide preparation, staining, and microscopic analysis for genotoxicity assessments.- Conducted ad-hoc Molar Absorption Coefficient (MEC) photo safety assay screenings to support drug safety evaluations.- Applied proficiency in western blotting, qPCR, cell viability assays, and AlphaLISA immunoassay to support the wider Biology team goals. Show less

Alderley Park

Study investigator within the in vitro mammalian toxicology team conducting micronucleus and MLA genotoxicity assays with skills including cell culture, manual and automated slide analysis, DNA and FISH staining techniques. - Routinely performed and delivered non-GLP and GLP IVMN assays, in vitro human lymphocytes (HuLy), and mouse lymphoma toxicological studies to industry and client specifications.- Ensure adherence to standard operating procedures and laboratory governance… Show more Study investigator within the in vitro mammalian toxicology team conducting micronucleus and MLA genotoxicity assays with skills including cell culture, manual and automated slide analysis, DNA and FISH staining techniques. - Routinely performed and delivered non-GLP and GLP IVMN assays, in vitro human lymphocytes (HuLy), and mouse lymphoma toxicological studies to industry and client specifications.- Ensure adherence to standard operating procedures and laboratory governance requirements.- Maintained accurate, timely laboratory records and study documentation.- Assisted the in vivo team with bone marrow slide preparation and manual scoring.- Collaborated with study directors on study scheduling, turnaround timelines, compound management, and training junior staff. Show less

Basel

Research internship in the Genetic Toxicology and Photosafety (GTPS) group within the Preclinical Safety department of Novartis Institutes for Biomedical Research (NIBR). The project aimed to investigate the in vivo genotoxicity profile and possible mode of action of an intermediate synthesis compound, which tested positive for gene mutation in the Ames test. The non-GLP study utilized a newly validated in vivo genotoxicity method, the Pig-a gene mutation assay with the integration of… Show more Research internship in the Genetic Toxicology and Photosafety (GTPS) group within the Preclinical Safety department of Novartis Institutes for Biomedical Research (NIBR). The project aimed to investigate the in vivo genotoxicity profile and possible mode of action of an intermediate synthesis compound, which tested positive for gene mutation in the Ames test. The non-GLP study utilized a newly validated in vivo genotoxicity method, the Pig-a gene mutation assay with the integration of the Peripheral Blood Micronucleus Test (PBMNT). Show less

Master Of Biological Sciences (Mbiolsci - Integrated Masters), Biological And Biomedical Sciences, 2:1

Activities and Societies: Peer Assisted Learning (PAL) Leader LINKS St John's Ambulance Society Biological Sciences Society - Social Media.

A-Levels, Psychology

Activities and Societies: Student Ambassador 2012-2013