Thesis: Immunotherapeutic Glycomaterials for Severe Traumatic Brain Injury (sTBI) Repair.Publications:1. Gonsalves N., Sun M.K., Chopra P, Latchoumane C.F.V., Bajwa S., Tang R., Patel B., Boons G.J.B., & Karumbaiah L. Neuritogenic glycosaminoglycan hydrogels promote functional recovery after severe traumatic brain injury. (Manuscript Under Review)2. McCrary, M. R., Jiang, M. Q., Jesson, K., Gu, X., Logun, M. T., Wu, A., Gonsalves, N., Karumbaiah, L., Yu, S. P., & Wei, L. (2022).… Show more Thesis: Immunotherapeutic Glycomaterials for Severe Traumatic Brain Injury (sTBI) Repair.Publications:1. Gonsalves N., Sun M.K., Chopra P, Latchoumane C.F.V., Bajwa S., Tang R., Patel B., Boons G.J.B., & Karumbaiah L. Neuritogenic glycosaminoglycan hydrogels promote functional recovery after severe traumatic brain injury. (Manuscript Under Review)2. McCrary, M. R., Jiang, M. Q., Jesson, K., Gu, X., Logun, M. T., Wu, A., Gonsalves, N., Karumbaiah, L., Yu, S. P., & Wei, L. (2022). Glycosaminoglycan scaffolding and neural progenitor cell transplantation promotes regenerative immunomodulation in the mouse ischemic brain. Experimental Neurology, 357, 114177. https://doi.org/10.1016/j.expneurol.2022.114177 3. Gonsalves N., Stachowicz K., Ramasubramanian S., Tang R., Karumbaiah L. (2023). ‘Inflammation induced extracellular matrix disruption and blood brain barrier breakdown after severe traumatic brain injury’ [Abstract Author Index: P04.294 (National Neurotrauma Symposium 2023)]4. Gonsalves N., Goodnight B. & Karumbaiah L. (2022). Glycosaminoglycan sulfation differentially regulates FGF-2 mediated human neural stem cell (hNSC) proliferation and cell cycle progression [Abstract Index- 757 (Society for Biomaterials, Annual Meeting 2022)]Awards:2024 RBC/ADS Symposium- 1st Place Poster Presentation 2024 UGA Summer Research Grant 2023 Regenerative Engineering and Medicine Annual Retreat - 1st Place Poster Presentation 2023 UGA RBC/ADS Annual Symposium - 1st Place Poster Presentation 2022 UGA Franklin Foundation Neuroimaging Fellowship Award2022 9th Annual International Symposium on Regenerative Rehabilitation (AR3T) - Travel Award2022 UGA Graduate School Travel Award2022 Regenerative Engineering and Medicine Annual Retreat - 3rd Place Poster Presentation Show less

1) Using an in-silico approach to understand the molecular interactors associated with pigmentation related pathways, performing literature curation and collation of genes to generate a network.2) Understanding drug-protein interactions using STITCH/STRING/CTD databases, compound and protein separation followed by compound ranking, curating proteins, sorting naturals using IMPPAT, Dr. Dukes, TCMSP and generating a network map using CYTOSCAPE.3) Skin olfactory receptors (ORs) and… Show more 1) Using an in-silico approach to understand the molecular interactors associated with pigmentation related pathways, performing literature curation and collation of genes to generate a network.2) Understanding drug-protein interactions using STITCH/STRING/CTD databases, compound and protein separation followed by compound ranking, curating proteins, sorting naturals using IMPPAT, Dr. Dukes, TCMSP and generating a network map using CYTOSCAPE.3) Skin olfactory receptors (ORs) and modulation of skin functions. Show less

1) Coaching and mentoring students of Grade 8 and 9 for Science and Mathematics2) Working as a part-time office assistant - Management

1) Performed in-silico analysis of short chain fatty acids using STITCH database to understand the role of SCFA in regulating multiple skin functions.2) Literature curation of the proteins interactors associated with SCFA and pathway analysis.3) Set up hypothesis elucidating the role of SCFA in driving multiple skin benefits.4) Shortlisted naturals as a source of SCFA using IMPPAT and Dr. Dukes database.5) Analyzed Mintel's GNPD data for naturals used in skin care… Show more 1) Performed in-silico analysis of short chain fatty acids using STITCH database to understand the role of SCFA in regulating multiple skin functions.2) Literature curation of the proteins interactors associated with SCFA and pathway analysis.3) Set up hypothesis elucidating the role of SCFA in driving multiple skin benefits.4) Shortlisted naturals as a source of SCFA using IMPPAT and Dr. Dukes database.5) Analyzed Mintel's GNPD data for naturals used in skin care industry.6) Submitted a full internal review paper on the project. Show less

1 ) Performed molecular biology, microbiology, immunology and cell biology techniques to understand the role of DNA-PK and Topoisomerase-2B in driving chemo resistance in patients suffering from Acute Myeloid Leukemia using chemoresistant leukemic cell lines.2) Contributed and gained interesting insights on the role of epigenetic gene regulation in driving chemoresistance in cancer cells.