Nathaniel Myers Email and Phone Number

Biomaterials Development and Characterization• Optimized a single-stage emulsion synthesis for a bioresorbable extended-release drug delivery platform (first author publication in NanoSelect)• Accessed biocompatibility and cytotoxicity of a drug delivery platform in-vitro and via explanted articular cartilage• Developed novel use of fluorescently activated cell sorting to determine in-vitro efficacy of surface-attached and entrapped materials • Accessed cytotoxicity on unique collagen hydrogels seeded with cells (PC3, MCF7)• Collaborated across institutions to develop a computational model to corticosteroid release from a novel biomimetic BPG-10 drug/carrier construct – leading to upcoming submission to Biomaterials• Applied computational models to access effects of various surface modifications on drug release from a poly(lactic-co-glycol acid) extended-release drug delivery platform• Generated a novel predictive model using pharmacodynamic data to predict resultant plasma cortisol levels post intra-articular corticosteroid injections using extended-release or free forms• Performed cell culture of various human cell types including PC3, Jurkat, MCF7 Drug Delivery Platform Efficacy • Developed novel uniaxial diffusion into tissue measurement model – leading to new discovery of micron sized drug carriers penetrating healthy bovine femoral articular cartilage• Employed computational modeling to determine diffusion rates of drug carriers into healthy articular cartilage• Generated and accessed an IL-1β induced autoimmune model for explanted bovine femoral articular cartilage• Utilized an explant model to determine efficacy of corticosteroid-loaded poly(lactic-co-glycolic acid) microspheres using qPCR, histology, immunohistochemistry, and microscopy techniques (drafted first author paper)

• Researched clinically translatable biomaterials for ocular and otic drug delivery Includes: microparticles, hydrogels, various drugs, and regenerative medicines• Modeled a novel dual-phase applicator for a microparticle infused hydrogel drug delivery system• Synthesized unique copolymer gels tailored to desired characteristics and behaviors

Rotation 2 - Biologics Research and Development Engineering Co-op• Modeled prototypes from conception to completion using NX 8.5• Re-programmed existing medical equipment using C++• Applied various research articles into design features to meet required functionality for products under development• Performed and drafted various study protocols in support of newly released product (Rejuvesol ®) • Studied product usage and practitioner tendencies through cadaver research in surgical settings• Manufactured product prototypes using both manufacturing machinery and 3D printersRotation 1 - Post Market Engineering Co-op• Created and implemented post market design changes for product improvement• Documented new product development release for hip exposure instrumentation• Prepared quality assurance documentation for FDA audit readiness• Authored product analysis reports for returned damaged products

Supported creation of proposals for government clientsDeveloped an improved company website using both HTML and Java Script

Maintained and repaired various types of medical equipment and computers