Nathaniel Xander Email & Phone Number

Philadelphia, Pennsylvania, United States

At Chimeron Bio we develop self-amplifying RNA (saRNA) therapeutics, encapsulated in a virus-like particle, with focuses on vaccines, rare disease, and immuno-oncology.My primary role is supporting our teams by performing quality control on our saRNA particles. I developed an SOP for RNA isolation and analysis with digital PCR. In addition to this method I have written and optimized several other SOPs. The experimental work I do consists of cell transfections, cell transductions and… Show more At Chimeron Bio we develop self-amplifying RNA (saRNA) therapeutics, encapsulated in a virus-like particle, with focuses on vaccines, rare disease, and immuno-oncology.My primary role is supporting our teams by performing quality control on our saRNA particles. I developed an SOP for RNA isolation and analysis with digital PCR. In addition to this method I have written and optimized several other SOPs. The experimental work I do consists of cell transfections, cell transductions and immunoassays such as fluorescence microscopy, ELISA, qRT-PCR, and flow cytometry. For my experimental work, I design and execute my own experiments which is followed by data analysis, interpretation, and presentation. I collaborate very closely with my colleagues to develop experiments, assays, and interpret data. I organize my data and present it at weekly lab meetings and engage in discussions to design future experiments and next steps. I also managed a project where we used our particle to produce large, difficult to produce proteins for a collaborator. We were successfully able to use our technology to make these proteins which added yet another capability of our particle.Additionally, being at a small company requires me to perform a lot of troubleshooting and problem solving on a day to day basis. Show less

I train AI models to accurately answer prompts for molecular biology related questions. I rate the quality and accuracy of the responses given. I also engineer complex prompts for the model to train.

Collegeville, Pa

I characterized novel drug targets with strong genetic association to disease within the Novel Human Genetics Department. I used wet lab techniques to investigate our targets and their role in a variety of human diseases. Additional, I developed ELISAs to be used for pharmacodynamics of potential therapeutics against our target.

Greater Philadelphia Area

Greater Philadelphia Area

Philadelphia, Pa

Analyze samples of blood samples and alveolar type two cells from patients that do not smoke, smoke, or have chronic obstructive pulmonary disease in order to understand the mechanisms of the progression of the disease. Here we investigated DNA damage and repair using western blotting.

Tübingen, Germany

Test for the presence of the systemin receptor in plants of the Solanaceae family. Tests performed included ROS and ethylene response. Other experiments included are DNA extraction, PCR, western blotting, and transient expression.

Guide and motivate students to perform proper snowboard maneuvers while promoting fun and safety. Demonstrate snowboarding techniques using multiple teaching methods to accommodate for different learning abilities. Recommend exercises to improve snowboarding ability.

Master'S Degree, Biotechnology

Bachelor Of Science - Bs, Biochemistry

Activities and Societies: Member of Delta Phi Alpha National German Honor Society Spring 2016 Semester Abroad in Tuebingen, Germany Temple.