Nikolaos Biris Email & Phone Number

Structural biologist/Protein chemist with a biophysics background and a focus on hit discovery and lead optimization within multi-disciplinary teams. Extensive experience on the study of protein-ligand interactions and the structural and dynamic characterization of binding. Proficient in production and characterization of monoclonal and bispecific antibodies as well as antibody-drug conjugates.Expertise in managing cross-functional teams and designing all aspects of gene-to-structure workflows.Creative problem solving and troubleshooting applied to challenging projects in a start-up company environment using structural and biophysical methods.Demonstrated success in the use of multiple techniques:Mammalian cell culture, Protein chemistry, Protein purification, construct design, Biologics, fragment-based screening, structure-based drug design, NMR spectroscopy, Isothermal Titration Calorimetry (ITC), MicroScale Thermophoresis (MST), X-ray crystallography.

Listed skills include Protein Chemistry, Protein Expression, Protein Purification, Biochemistry, and 34 others.