CRIO, Office of the Vice Chancellor for Health AffairsDirector, Center for Research Informatics, Office of the Vice Chancellor for ResearchUniversity of Illinois at ChicagoChicago IL, May 2013 to Present• Provide director level leadership, management and oversight for the planning, development and implementation of information technology driven policies, systems, programs, and platforms to accelerate translation of healthcare related research. • Key research stakeholder in Meaningful Use and ICD9 to ICD10 conversion, ensuring advocacy for data, research, and analytics supporting data integration and extra-operational initiatives.• Implement Natural Language Processing of clinical notes into SNOMED using cTAKES and MetaMap, and integration with HL7/ADT data, to investigate coding disparities between claims data and clinical notes.• Develop and implement Big Data initiative to complement Data Warehousing with development of “Data Lake” using Hadoop framework to integrate disparate data sources to feed into analytics and business intelligence.• Integrate data from EPIC, Cerner and McKesson systems to bring together clinical data, professional billing data and technical claims data to support Population Health and healthcare delivery science initiatives.• Spearhead Data, Research and Analytics by recruiting and developing a team to perform financial and claims analysis for Medicaid population to help develop metrics for managed care and accountable care (MCO/ACO) programs. • Develop alternative payment models to help negotiate care management fees and shared savings with payers.• Build dash-boarding and reporting solutions to track quality, efficiency, and care outcomes – triple aim.• Develop and analyze systems recovery plan to ensure restoration of research services in the event of failure of IT component or disasters.• Help organize Data Governance process at UI Health, with respect to Access, Integration, Security/HIPAA, Visualization and Quality.

Director for Biomedical Informatics, Office of the Vice Chancellor for ResearchAssociate Director for Research, Center for Clinical & Translational ScienceInformatics Director, Cancer CenterUniversity of Illinois, University of Illinois at Chicago, University of Illinois Hospital & Health Sciences SystemChicago, IL, Sep. 2011 to Present• Contribute to long term biomedical informatics plans – Organization, operation, recruitment and supervision of staff by anticipating, assessing, and planning for future needs.• Architect, manage and analyze overarching infrastructure needed to develop a clinical research data warehouse, allowing integration of all clinical, translational and basic sciences research data for the benefit of researchers across the University of Illinois Hospitals and Health Sciences System.• Lead the design, development, and use of various open source and vended solution software projects to ensure the development of tools to abstract phenotypes and inter-phenotypic relationships from the University of Illinois Hospital and Health Sciences System electronic medical records.• Support the development and deployment of system-based tools for researchers to easily analyze clinical data for de-identified population statistics including access to powerful computational resources integrated with user-friendly visualization, data management, and analysis tools.• Develop, support, and manage broad bioinformatics analytical activities, with emphasis on genomics and next-generation sequencing, functional image analysis, and study research.• Design, document, implement, analyze and administer bioinformatics projects to pipeline activities from small scale to large scale. • Establish and oversee the delivery of a bioinformatics analytics core for the University working with the Research Resources Center at Office of the Vice Chancellor for Research.

Director, Special Projects, Center for Research Informatics – University of ChicagoDirector, Initiative in Biomedical Informatics – University of ChicagoCo-Director, Bioinformatics Research Development Facility – University of ChicagoInformatics Director, Cancer Genomics Core – University of ChicagoChicago, IL, Sep. 2007 to Sep. 2011Associate Director, Biomedical Informatics, Computation Institute – University of Chicago/Argonne National LabsChicago, IL, Oct. 2009 to Sep. 2011• Manage and Architect overarching infrastructure to integrate and share bioinformatics and translational research data across various institutes, such as Argonne National Laboratories, University of Chicago, and UC Hospitals. • Provide bioinformatics platform via procurement or development for all departments of the Biological Sciences Division (BSD) including the Human Genetics department.• Coordinate the inter-operability and integration with various institutes such as Computation Institute (CI) and Institute of Genomics and Systems Biology (IGSB).• A Chief decision maker and advisor concerning matters of IT, and software development and bioinformatics• Responsible for management of multiple software and informatics projects. Advise and collaborate with various departmental IT teams. Serve the institute in a customer/client/stakeholder model with SLAs and other accountable contracts.• Work directly with various Deans and the Chief Research Informatics Officer, as well as the CIO of the Research Hospitals to develop the forward looking bioinformatics vision and design the Enterprise Clinical Data Warehouse.• Manage the High Performance Computing Facility, BRDF, making sure that it can scale and satisfy the informatics needs of the biological sciences community.

Arius Research is a Cancer research and development company, recently acquired by Roche for $200 Million. Arius division of Roche specializes in monoclonal antibody development. Was effective CIO for the organization:• Manage two departments - Information Technology and Bioinformatics, reporting directly to the CFO and VP of Research and Development.• Chief decision maker and advisor concerning matters of IT, and software development and bioinformatics. • Responsible for management of multiple software and informatics projects. Including complete project lifecycles, from planning, requirements gathering, assembling teams, to project completion and support.Managed the following departments: BIOINFORMATICS SOFTWARE DEVELOPMENT, TORONTO, ON• Manage and coordinate multi-disciplinary teams on creating experiment-based reporting system to gather reports on lead compounds from all sources in R&D. • Collaborate with biologists, statisticians, and mathematicians and create data mining and analysis engine software for data driven approach to scientific understanding.INFORMATION TECHNOLOGY, TORONTO, ON• Spearheaded transition from outdated organization-wide and departmental technologies to highly functional, streamlined and cost-effective client-server technologies and business solutions.• Implemented redundant ISP solutions and VPN services. And other operational and infrastructure projects. • Deployed entire VOIP communications system with remote monitoring and VPN administration.

Blueprint Initiative at Mount Sinai Hospital, a $30 million Genome Canada funded project to develop systems to capture proteome and biomolecular interaction data:• Deploy Software Configuration Management (SCM) and project management tools and practices; exercise bug tracking, version control, status auditing, and other methodologies to the Software Development Life Cycle (SDLC) of all projects.• Manage teams, clients, and other stakeholders and aid in effective marketing.• Lead and mentor team of developers, by teaching effective software design and architecture skills. An active participant in conferences and seminars for professional development.Highlighted projects managed at the Blueprint Initiative at the Mount Sinai Hospital: SIGNAL TRANSDUCTION KNOWLEDGE ENVIRONMENT PROJECT, AAAS/SCIENCE JOURNAL, WASHINGTON D.C.• STKE or Signal Transduction Knowledge Environment is an information system which covers signal transduction in biology, allowing study of how cells control their own and each others’ behaviors through chemical signals. BIOMOLECULAR INTERACTION NETWORK DATABASE: BIND, GENOME CANADA, TORONTO, ON • BIND facilitates the understanding of molecular interactions and pathways involved in cellular processes and will eventually give scientists a better understanding of developmental processes and disease pathogenesisHIGH THROUGHPUT BIOLOGY, BLUEPRINT INITIATIVE, TORONTO, ON / SINGAPORE• Develop scalable, robust systems to manage data generated from high throughput biology experiments with failsafe process flow control procedure

• Managed project team and tracked team member performance by exercising management skills consisting of group facilitation, training, and completion of performance appraisals. Created a staffing management plan outlining roles and responsibilities taking into consideration enterprise environmental factors.• Defined project scope while subdividing major project deliverables into manageable components, from initiation phase to completion phase. Provided a cost-benefit analysis while taking into consideration process boundaries and quality audits. Constructed complex Work Breakdown Structure (WBS) templates for integration of business processes and information systems.• Prepared a risk response strategy, including a contingent response strategy for the SDLC of the projects. Monitored level of risk, complete with recommended corrective actions and preventive actions, and reported project status to stakeholders throughout each project’s life cycle.Managed the following projects for MDS Proteomics Inc. and their clients: PIRANHA PROJECT, MDS PROTEOMICS, TORONTO, ON/ODENSE, DENMARK• Software to view and assess quality of data generated by an interaction proteomics technology platform, “PathMap”, in a way that is meaningful for biological analystsMOLECULAR COMPLEX VIEWER, BLUEPRINT INITIATIVE, TORONTO, ON• Application to view molecular complexes that were discovered and stored in the database. The model was capable of distinguishing between spoke model and binary pair interactions.AZBIND, ASTRA ZENECA INC., WALTHAM, MA• Employed a team of 8 individuals, which included 4 developers and 4 scientists, to provide a customized platform for analysis on client specified drug targets

• Worked on Human Genome Project, specifically on Chromosome 7 project.• Development of bioinformatics analysis tools and engines. Integration of multiple applications to create software for large scale sequence analysis. Developed sequence annotation portal suite, Gene Script.• Developed custom software for researchers, students and facilities of TCAG and the BiSC: Bioinformatics Super Computing Centre (currently known as the Centre for Computational Biology).