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Associate Principal Scientist "Digital Champion" in Pharmaceutical Sciences at AstraZeneca Macclesfield.Background in HTE and synthetic organic chemistry from pre-hit to process chemistry, and from experimental design and automated dosing through to full analysis and visualization for rational, mechanism-driven reaction optimization. Aim to inspire collaboration between diverse functional teams for mutual benefits. To this end, working regularly with other departments including IT, discovery sciences, sourcing, and others. Creating bespoke, interactive data visualizations to effectively communicate dependent variable (multi)parameter relationships. Coding in Python and R for automation of the boring stuff to free up scientists' time. Working with SQL and Snowflake databases. Previously responsible for multiple CapEx projects and regular equipment management and maintenance. Worked in teams for several global projects, including in-house eLN, workflows for chemistry automation, and data architecture transformation. Familiar with Mettler Toledo/Axel Semrau Quantos series, Unchained Junior/Big Kahuna, Chemspeed systems, Amigochem, Formulatrix Mantis, and more.• Regular presenter of invited talks at conferences and universities in the UK and internationally, on chemistry data, high-throughput experimentation, and automation.• One of two chemists awarded the Salters' Centenary Award 2022, for the potential to make an outstanding long-term contribution to the chemical industries.• Managed day-to-day experimentation as sole user of an automation laboratory, running 2.00 bespoke and rationally-designed plates per day (when not ask-limited).• Self-taught Python from 2018 to automate data workflows and obviate inefficient steps.• Scientific Advisory Board member, DeepMatter, and advisory board member, Chemical & Engineering News.• Committee member, RSC CICAG and RSC HSG.• Curate a number of web resources at https://supersciencegrl.co.uk, @ukchemjobs, and @ChemPostdocBot.• Former Team Leader and coach (while working in industry) of a committee of mostly students and postdocs at the historic Oxford University Scientific Society.• Until 2022, Scientific Editor at RSC Synthetic Reaction Updates, scouring the literature to curate novel or interesting organic transformations.• Freelance writer and editor, and regular columnist for Chemistry World.• Organizer of UK National Retrosynthesis Competition (2021 - 2024) and Automated Intelligent Chemistry conference (2020).
Astrazeneca
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Associate Principal Scientist "Digital Champion"Astrazeneca Oct 2022 - PresentMacclesfield, England, United Kingdom -
Automated Data Workflow SpecialistSyngenta Feb 2022 - Sep 2022Bracknell, England, United KingdomResponsible for reaction optimization, data management, and workflow automation in a growing laboratory. Reaction optimization expert for all stages of agrochemical discovery and beyond. Enhanced data analysis practices using Spotfire, Virscidian Analytical Studio, and Python and Plotly Dash scripting. Active member of several global strategic teams, eg: global data management strategy, LIMS system, connecting lab equipment with webtools and workflows, external speaker committee. Responsible for multiple CapEx projects. Regularly liaised with other departments (eg: analytical, process studies, biosciences). Lead of the Syngenta global Catalysis Network. -
Principal Research ScientistSyngenta Jun 2021 - Feb 2022Bracknell, England, United Kingdom -
Senior ScientistSyngenta May 2020 - Jun 2021Bracknell, England, United Kingdom -
Scientific Editor, Synthetic Reaction UpdatesRoyal Society Of Chemistry Apr 2020 - Jan 2022(Additional contract while working at Pfizer and Syngenta.) SRU was a monthly set of new, updated, and useful tools to add to your synthetic chemistry repertoire. Scientific Editors selected the most useful synthetic organic transformations from across the month's literature & shared them via monthly alert and a searchable database. SRU stopped operating in Jan 2022. -
High-Throughput Experimentation ChemistPfizer Jun 2019 - May 2020Sandwich, UkResponsible for high-throughput experimentation: complete experimental design through to full dataset analysis for process chemistry. Designed and executed HTE for reaction optimization, solvent replacement, and detailed process understanding. Learned Python and R to fully automate the HTE software workflow, and introduce new visualization capabilities. Performed continual maintenance and repair of glovebox, and automation and LC-MS systems. -
Research Scientist IAmri (Albany Molecular Research Inc.) Mar 2017 - May 2019Erl Wood, Surrey, UkAMRI (now Curia). In-house contractor for Eli Lilly; sole UK chemist at Lilly performing high-throughput experimentation using laboratory robots for reaction optimization, using only bespoke plate designs. Average 1.50 plates per day (usually 96 vials, where bottleneck was number of requests; 2.00 otherwise), from experimental design to full analysis and result communication. Actively collaborative and international role with projects from pre-hit to process across three main Lilly R&D sites. Sole user and responsible for maintenance of the automation laboratory (5 robots, 2 PolyBLOCK plates, 2 LC-MS systems, and a 10-glove glovebox). Provided fast and robust discovery target synthesis and route design both with and without the assistance of automation. Particular knowledge gained in the area of cross-coupling.
Nessa Carson Skills
Nessa Carson Education Details
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Organic Chemistry -
Chemistry
Frequently Asked Questions about Nessa Carson
What company does Nessa Carson work for?
Nessa Carson works for Astrazeneca
What is Nessa Carson's role at the current company?
Nessa Carson's current role is Digital Champion for Pharmaceutical Sciences at AstraZeneca.
What is Nessa Carson's email address?
Nessa Carson's email address is nc****@****ois.edu
What is Nessa Carson's direct phone number?
Nessa Carson's direct phone number is +187233*****
What schools did Nessa Carson attend?
Nessa Carson attended University Of Illinois At Urbana-Champaign, University Of Oxford.
What skills is Nessa Carson known for?
Nessa Carson has skills like Chemistry, Organic Chemistry, Organic Synthesis, Project Management, Science Writing, Synthetic Route Design, Nmr Spectroscopy, Air Free Techniques, Organometallics, Precision Metalwork, Gas Chromatography, Gc Ms.
Who are Nessa Carson's colleagues?
Nessa Carson's colleagues are Magnus Mällström, Patrick Bergeron, Refilwe Mutloane, Mara Rados, Jennifer Guinup, Marcello De Matteis, Hugo Romero.
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