o Panacea-ml revolutionizes clinical trial design with its data-driven, explainable-AI SaaS platform. Its cutting-edge AI technology addresses the primary causes of clinical development failure by identifying patient profiles that maximize therapeutic efficacy, minimize safety risks, and improve participant retention. Leveraging historical clinical trials and over 1 million real-world patient health records, Panacea-ml's AI model enhances patient selection criteria, reduces cohort sizes, and uncovers novel marker-endpoint interrelations, surrogate markers, and causal relationships beyond simple statistical correlations

Investing in early-stage "must-have" digital health innovations

Head Diagnostics is developing innovative technology and an associated handheld medical device for the diagnosis of concussion (mTBI) and Parkinson’s Disease (PD). This novel technology will provide for rapid assessment and assist clinicians in making objective diagnoses of brain disease and brain impairment.

Industry Advisory Board Member of this leading digital health company developing smartphone applications for the diagnosis and management of respiratory disease until acquisition by Pfizer. ResApp’s machine learning algorithms use sound to diagnose and measure the severity of respiratory conditions without the need for additional hardware. Clinical studies at leading hospitals have demonstrated accurate diagnosis of pneumonia, asthma/reactive airway disease, bronchiolitis, croup, chronic obstructive pulmonary disease and upper respiratory tract infections. ResApp has also obtained excellent results for screening of obstructive sleep apnea in a double-blind, prospective clinical study.

Advisory board member to this leading digital health start-up that diagnoses neurodegenerative diseases non-invasively using a proprietary algorithms for analyzing typing patterns.

Providing digital health strategy and innovation infrastructure management consulting services to a range of healthcare clients including, pharma, providers and start-ups.Recent Consulting Engagement:♦ Roche Pharmaceuticals: Advising on digital healthcare and digital-knowledge management strategy. Creating strategic frameworks for building competencies and capabilities for a robust digital health program. Advising client on potential innovative digital health pilot projects to address unmet needs in various therapeutic areas.♦Children's Hospital of Los Angeles: Development of a strategic plan for a robust, enterprise innovation program. Providing strategic guidance on program vision, goals, programs, structure, organization, staffing, and budgets.♦Merck, Roche and others: Advice on emerging trends in healthcare innovation and digital health in the pharmaceutical industry.

Led five functions catalyzing innovation to support patients, healthcare professionals, and partners.• Developed strategy and led the “Innovation Beyond the Molecule” program to deliver non-pharmacological value to patients and providers. - Launched the “Patient Center” to respond to inquiries about access to pipeline compounds. - Identified, evaluated, and pursued licensing of novel digital health solutions to assist MS patients manage depression and fatigue. Built financial model and engaged internal stakeholders in concept. - Conceived of novel mechanism to leverage tele-health for patient medication adherence in clinical trials.• Managed Medical Information group that responds to all product inquiries. Oversaw development of globalization strategy for managing medical information needs across many countries and languages, with goals to reduce redundancies and improve compliance and communication• Oversaw Scientific Meetings group responsible for executing non-commercial presence at scientific meetings. Directed the creation of cross-functional (medical, commercial, global, regional, public relations, etc.) “Congress Governance” team to set high-level strategy and policies• Led two teams: the External Partnership group responsible for engagement with clinical thought leaders and the Medical Education group that supports continuing, physician medical education.

Conceptualized strategy, built, led and drove first of its kind, nationally recognized program to accelerate innovation in care delivery. Created infrastructure and environment where innovation flourished, supporting both individual innovators and strategic institutional initiatives.• Launched and managed innovation seed fund to support doctors, nurses, and researchers in testing new ideas in clinical care -Established and chaired fund’s investment board. Oversaw all aspects of fund management including finances, due diligence and communications -Provided guidance through implementation and commercialization, resulting in several patents and licenses for 37 projects• Created and managed Fasttrack Innovation in Technology (FIT) program to rapidly build novel clinical software solutions and mobile apps - Oversaw software development team which built prototypes and supported pilots - Prototyped 9 new digital health solutions to improve clinical efficiency and/or enhance patient experience. Scaled and pursued commercialization of successful pilots• Developed organizational telehealth strategy and launched 10 pilot projects in both direct virtual care of patients at home and clinician-to-clinician, virtual consultations - Convened and lead the multi-disciplined Telehealth Task Force and subcommittees - Oversaw conceptualization and launch of 10 pilots including selection of hardware and software, design of clinician workflow, user training, and resolution of legal, compliance, and financial issues - Developed payment model strategy. Pursued legislative changes to support reimbursement. Wrote and received a multi-payer, multi-year grant• United, grew and educated innovation community through creation of monthly Innovation Forums, Innovation Day, Innovators' Showcase, and a virtual collaboration site. Supported 2 hackathons• Supported founding of International Society for Pediatric Innovation, a consortium of 30+ pediatric hospitals

Advised organization on development of a strategic, system-level, clinical innovation program. Evaluated opportunity and organizational readiness for creation of a centralized innovation program focused on increasing rate and impact of innovation and learning. Examined existing entity-level innovation programs at Partners and benchmarked system-level innovation programs to those at other large healthcare organizations.

Built and led a team of clinicians and technologists charged with identifying and assessing emerging clinical technologies and presenting them to operational leaders. Built and drove the organization's first innovation program. Managed the establishment of an internal $5M innovation fund. Oversaw technical staffing and governance of new Garfield Innovation Center, a 37,000 sq. ft. test lab to prototype new technologies, design, and workflow. • Identified focal areas for innovation and promoted and educated organization on potential impact of innovation• Oversaw team that conducted primary research into emerging technologies, publishing white papers on the relevance of new technologies• Initiated and directed innovation projects including “Operating Room of the Future” and “Interactive Patient Care Project”• Formed and led 40 person Telehealth Working Group, a multi-discipline, cross-regional strategy group that formulated tactical and strategic five-year telehealth plan • Created infrastructure for innovation fund, chaired investment Board and oversaw all aspects of fund management including finances, due diligence, communications, and launching of 13 projects • Organized and chaired semi-annual innovation conference for top IT and clinical leadership, Developed agenda, themes, arranged speakers and served as a keynote speaker• Built “Clinical Advisory Counsel” comprised of doctors, nurses, and pharmacists to provide bi-directional communication on technology innovations.• Established a strong “innovation community” throughout organization. Identified and launched a successful internal social-networking tool to improve communication within the community

Commercialized Archimedes mathematical simulation model for pharmaceutical and healthcare customers. Developed business plan, financial model, marketing and sales strategy. Negotiated contracts and managed relationships with pharmaceutical companies, non-profit organizations, and government customers. Guided deliverable of projects and services to customers. Managed hiring, growth, and spin out of unit into a for-profit company.• Led unit from 0 to $2M+ in revenue in 1 year • Negotiated most aspects of complex spin out from within organization; contracts with American Diabetes Association for national web-based tool; and complex partnering agreements with Pfizer, GSK and Lilly

Conducted due diligence on potential healthcare IT and services investments. Evaluated investments, focusing on technology, development stage, market potential, business model, competitive advantage, and management capabilities. Sourced new deals. Wrote reports on both positive and negative recommendations.

Managed company, oversaw technical development, marketing strategy, administration, and fundraising for e-clinical trial start up. Negotiated with other potential customers, partners, and investors.• Revised business and financial models and re-wrote business plan.• Negotiated and managed strategic partnership with Eli Lilly, resulting in a Phase 3 clinical trial and Lilly’s strategic investment in the company.• Explored partnership opportunities and secured revenue-generating, non-exclusive licensing agreement. • Oversaw patent filings and IP strategy.• Led fundraising activities, including pitching to VCs and angels. Negotiated term sheets.Prepared new CEO to take over.

Performed deal review and due diligence for investment in medical device and healthcare firms. Evaluated industry trends and identified emerging investment opportunities. Board level/CEO advisor to various portfolio companies on strategic partnerships, web-based revenue models, marketing, strategy, and fundraising including: • Landmark Healthcare Board/CEO on development of new business models, products, markets, and channels for complimentary, alternative medicine services• Home Healthcare Laboratory of America CEO in preparation of business plan and fundraising strategy for over-night specimen testing provider• Gordian Healthcare CEO in fundraising efforts and review of strategic partnership opportunities for risk/disease management tools for employers

Managed formation of company spun out by Stanford School of Medicine to commercialize web-based medical information system developed by faculty. Initiated, negotiated, and completed contracts with distribution partners. Managed partnerships and assisted in marketing to large institutional customers. Ran company including hiring business and technical staff. Spearheaded launch of alpha version of product. Planned and managed development of beta version.• Wrote business plan and developed financial model• Negotiated a distribution license with Eclipsys. Renegotiated the distribution license when Eclipsys spun out HealthVision• Negotiated with content publishers including the British Medical Journal, Oxford University Press, and others. Successfully negotiated an unprecedented deal with Scientific American to license medical text book content for on-line use.• Negotiated with Micromedix and Lexicomp to license drug databases for on-line use. Signed deal with Lexicomp• Negotiated with Stanford University a novel, equity-based technology license. Oversaw legal aspects of spinning SHINE out of Stanford Medical School to create an independent company