Nicholas Rouse Email & Phone Number

Sandy Springs, Ga, Us

Burlington, North Carolina, Us

Oversee the development, validation, and production of next-generation sequencing bioinformatic pipelines.__________________________________________________________________________NGS tests brought to market:*Inheritest 500 PLUS (Pan-ethnic carrier screening):-Single nucleotide polymorphism and small indel sequencing assessment-Copy number variant assessment-Congenital Adrenal Hyperplasia (CYP21A2)-Alpha thalassemia (HBA)-Fragile X Syndrome (FMR1)

Atlanta, Georgia, Us

Oversee the development, validation, and production of clinical next-generation sequencing bioinformatic pipelines.__________________________________________________________________________NGS tests brought to market:*Whole genome sequencing:-Constitutional whole genome variant analysis-Copy number-Expansion repeat analysis-Uniparental disomy-Mitochondrial heteroplasmy, deletion, and depletion analysis*Whole exome sequencing: -Constitutional exome variant analysis-Copy number-Uniparental disomy*Whole transcriptome sequencing: -Differential expression-Transcript analysis-Junction analysis-Variant analysis*Custom genetics panel-Constitutional variant analysis-Single exon resolution copy number*Mitochondrial analysis-Heteroplasmy (1 %) variant analysis-Break point resolution deletion analysis with quantification

New York, New York, Us

Developed and validated bioinformatic pipelines for next-generation sequencing clinical tests. All tests were approved by New York State.__________________________________________________________________________Validated clinical tests:*Whole exome sequencing: -Constitutional exome and copy number analysis*Cancer whole exome sequencing: -Constitutional exome, somatic variant identification, and copy number analysis-Transcriptome: confirmation of cancer specific genomic variants in tumor derived transcripts, identification of translocations resulting in chimeric transcripts, and identification of overexpressed transcripts in cancer samples*Custom genetics panel-Constitutional variant and copy number analysis

New York, New York, Us

Data analyst for next-generation sequencing clinical tests.

New York, New York, Us

Statistical analysis for validation of next-generation sequencing clinical tests.

Served as primary biostatistician on the study design and analysis for multiple research projects focused on improving serrated polyps methodology in handling / orientation / and classification criteria, which resulted in five publications.

Philadelphia, Pennsylvania, Us

Statistical planning and analysis for large scale program assessments.__________________________________________________________________________Main project was a 7-year (2007-2013) assessment on the writing of undergraduate business majors. During the course of the study more than 3,700 assessments were conducted on nearly 2,000 documents.Served as the primary statistician and coordinator of this large scale assessment from 2009-2013 (continued working on this project after full time position was completed).The resulting publication was awarded the Technical and Scientific Communication Award in the category of Best Article on Pedagogy or Curriculum in Technical or Scientific Communication at the 2018 Conference on College Composition and Communication.

Master Of Science (M.S.), Biostatistics

Bachelor Of Science - Bs, Mathematics

Education record