Nick Costantini

Nick Costantini Email and Phone Number

Multidisciplinary Scientist @ Abzena
cambridge, cambridgeshire, united kingdom
Nick Costantini's Location
Riverside, New Jersey, United States, United States
About Nick Costantini

I am passionate about science, and I help companies progress from discovery through clinical stages by synthesizing both simple and complex targets. I look forward to continuing my growth in the pharmaceutical and biotechnology industries.I have strong background in synthetic organic chemistry, solid-phase peptide synthesis, chemical biology, analytical chemistry, and chemical engineering. With my diverse skillset, I have been able to engage multidisciplinary groups (such as QA, QC, Analytical, manufacturing, and supervisors) to complete projects and achieve organization goals.I have had the opportunity to train under multiple SMEs in process scale up, API manufacture, and cGMP production. With all that I have learned in academia and industry, I have had the opportunity to train and mentor scientists of all levels.I have developed expertise in using and analyzing instruments such as HPLC, LC-MS, NMR (1D and 2D), flash chromatography. I have been responsible for HPLC repair, method development, and method transfer. I completed Advion's mass spectrometry training course where I learned to maintain and properly operate the Advion single quad mass spectrometer. I have experience using Hf calorimetry, TSU, UV-Vis, DSC, and TGA. I have successfully developed processes for cGMP campaigns that were successfully transferred to the pilot plant. I have operated and succeeded as a lead chemist in both the kilo laboratory and pilot plant.I am dedicated to my work, and I do what is necessary to successfully complete the job.

Nick Costantini's Current Company Details
Abzena

Abzena

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Multidisciplinary Scientist
cambridge, cambridgeshire, united kingdom
Website:
abzena.com
Employees:
287
Nick Costantini Work Experience Details
  • Abzena
    Scientist Ii
    Abzena Jul 2021 - Present
    Bristol, Pennsylvania, United States
    As a scientist at Abzena, I have worn many different hats including synthetic organic chemist, process development scientist, analytical scientist, laboratory equipment manager, hazwoper lead, and proposal writer. I have worked with a variety of cross functional teams to to successfully deliver projects for our clients. I have worked on a number of different programs synthesizing linker payloads for clients.
  • Flamma Spa
    Process Scientist
    Flamma Spa Oct 2019 - Jul 2021
    I was responsible for the process development and scale-up of pharmaceutical products. I performed HPLC and M/S analysis, repairs, maintenance, method development, and analytical method transfers. I successfully completed multiple projects in both the kilo laboratory and the pilot plant as a lead chemist. I developed the process, wrote, reviewed, edited, and executed batch records under cGMP. I trained and mentored colleages and junior scientists. I organized and coordinated a cross functional team consisting of manufacturing, analytical, QC, QA, and supervisors to successfully complete the site's first cGMP campaign.
  • University Of Delaware
    Research And Teaching Assistant
    University Of Delaware Sep 2016 - Jun 2019
    I used solution and solid-phase peptide synthesis (SPPS) to generate peptides for analysis. I purified and analyzed peptides via reverse phase HPLC (analytical, semi-preparative, and preparative). I characterized peptides with NMR (proton, carbon, TOCSY, NOESY) and ESI M/S. I operated as Zondlo lab safety officer and safety liaison between our lab and Environmental Health and Safety. I was responsible for both inventory management and HPLC repairs. I also managed, trained, and mentored an undergraduate student on her research project. I worked as a laboratory instructor to educate future chemists. I successfully developed and implemented a SPPS laboratory experiment for Organic Chemistry II students. I received the Elizabeth Dyer Teaching Award for my work.

Nick Costantini Education Details

Frequently Asked Questions about Nick Costantini

What company does Nick Costantini work for?

Nick Costantini works for Abzena

What is Nick Costantini's role at the current company?

Nick Costantini's current role is Multidisciplinary Scientist.

What schools did Nick Costantini attend?

Nick Costantini attended University Of Delaware, Rowan University.

Who are Nick Costantini's colleagues?

Nick Costantini's colleagues are Artsiom Nnumolu, Radhika Blevis-Bal, Tiffany Boll, Daniel Adcock, Laura Weatherburn, Alla Misyutina, Amanda Bohn.

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