Nicholas Costello Email & Phone Number

-Developed The Heights Hospital Lab from CMS 116 application to receipt of CLIA Certificate of Accreditation-Manage, train, and maintain competencies of all laboratory staff-Design and implement IQCPs, validations and performance verifications of lab instruments and test systems-LIS: Construct & design, instrument interfacing, service and maintenance-Author and maintain/review laboratory procedures-Design and modify test menu to support an increasing scope of services-Oversee transfusion service-Experience managing multiple laboratories-Instrumentation: Sysmex XP-300, Abbott i-Stat, Abaxis Piccolo, Alere Triage meter, Clinitek Status, Olo Sight.LIS: CPSI Evident, T-systems

Shenandoah, Texas, United States

-Began as evening shift supervisor coordinating a team of technologists and phlebotomists to provide comprehensive laboratory services in a trauma level II, 350 bed acute care hospital-Promoted to Microbiology/Urinalysis/Serology supervisor in November 2018, overseeing the quality and compliance of each department and tracking send out cultures.-Ensured completion and documentation of staff competencies-Delivered monthly quality reports and served as member of microbiology and hematology technical teams-Assisted validation of new procedure: SARS CoV-2 on Abbott ID Now-Assisted validation of new procedure: Automated body fluid cell count on iRICELL-Instrumentation: Siemens Vista 1500, Beckman DxH, Haemonetics TEG 5000, Ortho Vision, Beckman iRICELL Velocity, Abbott ID Now, Quidel SoFia, BioMerieux BacT/Alert

New Braunfels, Texas, United States

-Exemplified skills in blood bank, hematology, chemistry, coagulation, urinalysis and serology in providing laboratory services for a 150 bed acute care hospital-Delivered accurate test results within established turnaround times-Instrumentation: Abbott Architect ci4100, Sysmex XN-2000, Immucor Echo, Seimens BCSXP-LIS: Allscripts Sunrise, Haemonetics SafeTrace

San Marcos, Texas, United States

-Evaluate donor health and the safety of donor plasma by performing high volume serologic testing-Utilize GMP and GDP, optimal communication methods and efficient processes to meet FDA regulations and exceed compliance standards in a worldwide market-Instrumentation: Ortho Summit System, Helena SPIFE (SPE), Abbott Architect c8000 & PRISM system-LIS: Aurora AccLaIM (Stratec), EPIC

Austin, Texas, United States

-Supervised night shift laboratory staff servicing 200+ bed acute care hospital-Train new technologists and phlebotomists

Austin, Texas, United States

-Demonstrated proficiency in all areas of a complete medical laboratory including blood bank-Laboratory Safety Officer and Environment of Care representative (SNW; Mar 2009 - Apr 2013)-Instrumentation: Beckman Coulter Unicel DxC 600i Synchron & Access2, Sysmex XT-1800i, Stago Compact STA, ACL TOP300.-LIS: Sunquest, MiSys, Mediware Transfustion Software (HCLL)

College Of Pharmacy

-Explored the catalytic mechanism of dimethylargininase (DDAH); a significant enzyme implicated in blood pressure regulation, cell signaling, vascular disease progression-Engineered and purified variant DDAH enzymes using site-specific mutagenesis of active site residues-Performed steady-state kinetic testing of mutant DDAH enzymes with synthesized substrates-Assisted the development of a new assay for trapping intermediate structures formed during DDAH catalysis, which supported our hypothesis of a covalent interaction with substrate

Biology, General; Biochemistry, Enzymology

Activities and Societies: UT College of Natural Sciences Honors - September 2004 Undergraduate Research Fellow (University Cooperative.

Mls, Clinical Laboratory Science/Medical Technology/Technologist