• Led a team of scientists focused on supporting all stages of cell therapy process development for severe genetic diseases• Designed, executed, analyzed, and presented large scale DOE studies for cell therapy products• Authored scientific reports and regulatory sections to support both US and EU filings• Represented cell process development for CMC activities

• Led the design, development, and optimization of a novel collagen fiber scaffold platform for cardiac tissue engineering applications• Fabricated engineered cardiac tissues composed of stem cell derived cardiomyocytes in collagen and fibrin copolymer hydrogel scaffolds and characterize these tissues using a DOE approach paired with chemical, histological, and mechanical assays• Managed individual and teams of undergraduate students working on multiple projects simultaneously… Show more • Led the design, development, and optimization of a novel collagen fiber scaffold platform for cardiac tissue engineering applications• Fabricated engineered cardiac tissues composed of stem cell derived cardiomyocytes in collagen and fibrin copolymer hydrogel scaffolds and characterize these tissues using a DOE approach paired with chemical, histological, and mechanical assays• Managed individual and teams of undergraduate students working on multiple projects simultaneously, including the development of a mechanical stimulation bioreactor and empirical validation of compressible vessel flow characteristics using a novel physical modeling method• Independently designed, fabricated, and iteratively improved custom lab apparatuses through the application of CAD, laser cutting, and 3D printing technologies• Authored reports and presentations for leading academic journals and conferences Show less

• Led in the development and optimization of a process to manufacture a porous collagen tissue scaffold for an autologous cellular cartilage product• Designed and executed DOE studies to identify and optimize critical process parameters• Designed bench top assays to evaluate and characterize collagen scaffold materials• Designed and implement an automated image analysis method to collect quantitative data from optical microscopy images• Authored reports and presentations to… Show more • Led in the development and optimization of a process to manufacture a porous collagen tissue scaffold for an autologous cellular cartilage product• Designed and executed DOE studies to identify and optimize critical process parameters• Designed bench top assays to evaluate and characterize collagen scaffold materials• Designed and implement an automated image analysis method to collect quantitative data from optical microscopy images• Authored reports and presentations to communicate process development progress• Worked with suppliers to evaluate and purchase laboratory equipment and materials Show less

• Developed cell based biologic and medical device products• Performed development activities while implementing QbD principles• Utilized DOE methodologies to design optimal and efficient experiments• Executed experiment protocols and collected data following good documentation practices• Developed and implemented cell based assays• Wrote reports and presentations on findings for a variety of audiences

• Supported R&D and marketing teams with the testing of implantable medical devices in vitro and in preclinical models• Interfaced with surgeons, veterinarians, histopathologists, and vendors to design GLP, research only, and development study protocols• Contributed to the design of novel preclinical models of soft tissue repair applications• Managed all preclinical study documentation, vendor contracts, and specimens• Led in the creation of new protocols, reports, and… Show more • Supported R&D and marketing teams with the testing of implantable medical devices in vitro and in preclinical models• Interfaced with surgeons, veterinarians, histopathologists, and vendors to design GLP, research only, and development study protocols• Contributed to the design of novel preclinical models of soft tissue repair applications• Managed all preclinical study documentation, vendor contracts, and specimens• Led in the creation of new protocols, reports, and presentations• Assisted with surgery and sample collection for six large animal preclinical studies• Performed advanced image analysis and mechanical testing of tissues and devices to study the resorption characteristics of silk scaffold materials• Supervised work performed by external CRO's and internal laboratory staff Show less

• Supported R&D and marketing teams as a technical resource on multiple projects simultaneously• Designed and implemented novel experimental procedures for in vitro and in situ testing• Authored reports and constructed presentations to communicate effectively with a variety of audiences including R&D, marketing, and executive teams• Conducted competitive product analysis for biologic soft tissue scaffolds• Led technicians in sample preparation and test procedures• Provided… Show more • Supported R&D and marketing teams as a technical resource on multiple projects simultaneously• Designed and implemented novel experimental procedures for in vitro and in situ testing• Authored reports and constructed presentations to communicate effectively with a variety of audiences including R&D, marketing, and executive teams• Conducted competitive product analysis for biologic soft tissue scaffolds• Led technicians in sample preparation and test procedures• Provided technical assistance in preclinical and cadaver lab environments Show less

• Analyzed protein structure and mechanical characteristics of silk fibroin filaments produced via microfluidics• Fabricated PDMS microfluidic devices via soft lithography• Cultured mammalian endothelial cells on novel silk scaffold materials