Nicolas A. Morgenstern Email & Phone Number

Virtuleap is a health and education startup develping cognitive assessment and training using virtual reality and artificial intelligence. My role includes working with the game design team in the game concept design and development, data analysis and interpretation, providing scientific documentation, and writing in peer-reviewed journals and national and international presentations.KEYWORDS: Neuroscience research, Neuropsychological tests, Behavioral science, Data science, Machine Learning, Digital health, Virtual reality, Digital biomarkers.

Lisbon, Portugal

I led a research line to develop a new model for studying human neurophysiology in vitro and detect age-induced synaptic dysfunction underlying early cognitive decline in humans.KEYWORDS: Project management, Experimental design, Neuroscience, Neurophysiology, Electrophysiology, Optogenetics, Human induced neurons, Aging, Matlab programming, Data managing, Data processing, Signal processing, Data analysis, Data interpretation, Data presentation and visualization, Literature use and management, Scientific writing, Oral presentations.

Lisbon, Portugal

In this project, I unraveled a new corticostriatal circuit using optogenetics, electrophysiology, and pharmacology. This circuit is supported by a polysynaptic motif and conveys a second phase of excitation to striatal neurons through an acetylcholine-dependent glutamate release mechanism. These findings could have implications for behavior, plasticity, and learning. This work was published in Science Advances, a high-impact scientific journal: https://www.science.org/doi/10.1126/sciadv.abh4315KEYWORDS: Project management, Experimental design, Neuroscience, Optogenetics, Neuronal circuit mapping, Corticostriatal connection, Matlab programming, Data managing, Data processing, Signal processing, Data analysis, Data interpretation, Data presentation and visualization, Confocal / 2-photon imaging, Immunofluorescence, Viral vectors, Stereotaxic surgery, Transgenic mouse models, Literature use and management, Scientific writing, Oral presentations.

Lisbon, Portugal

I developed a new circuit mapping method that combines optogenetics and multiple patch-clamp recordings. I found that connected pairs of neurons in the cerebral cortex share more inputs from the thalamus than unconnected pairs, supporting current models of cortical processing. The method I developed opened new possibilities for research in this area. This work was published in Nature Neuroscience, a very high-impact scientific journal: https://www.nature.com/articles/nn.4339KEYWORDS: Project management, Experimental design, Neuroscience, Multiple patch-clamp recordings, Optogenetics, Circuit mapping, Thalamocortical connection, Matlab programming, Data managing, Data processing, Signal processing, Data analysis, Data interpretation, Data presentation and visualization, Confocal imaging, Immunofluorescence, Viral vectors, Stereotaxic surgery, Literature use and management, Scientific writing, Oral presentations

Buenos Aires, Argentina

Subject: Effects of ageing and neurodegeneration on neuronal plasticity in the hippocampus.Supervisor: Alejandro F. Schinder.My thesis was focused on understanding how neurons that are born postnatally in the dentate gyrusof the hippocampus integrate to a preexisting and fully functional circuit, and how ageing andneurodegeneration impact this plastic process.KEYWORDS: Project management, Neuroscience, Neurophysiology, Electrophysiology, Patch-clamp recordings, Synapse, Hippocampus, Adult Neurogenesis, Data managing, Data processing, Signal processing, Data analysis, Data interpretation, Data presentation and visualization, Confocal imaging, Immunofluorescence, Viral vectors, Stereotaxic surgery, Literature use and management, Scientific writing, Oral presentations.

Phd In Biological Sciences, Neuroscience

Doctor Of Medicine - Md

Industrial Design Technician