Nicolas Tan Email & Phone Number

Assessing feasibility and validating methodologies for testing potency of post-early development molecules within the Analytical Development Quality Control Department under Good Manufacturing Practices (GMP).Developed and parameterized an ELISA for testing Drug Substance component potency, authored TP for GMP method guidance and demonstrated equipment suitability for automated assay runtime.Generated and documented key experiments for tracking the development steps taken to be cited and used for Phase 1 Pre-clinical potency of the molecule in questionCell Banked cell lines for Potency assay development and SOP generation pertaining to cell line qualification and maintenance as well as molecular potency in a heavily regulated GMP environmentGenerated and debugged a Reporter Gene Cell-based Assay testing the formulation Mechanism of Action on the maintained cell line.Simultaneously demonstrated and developed on a different TP undergoing validation for Equipment and Reagent suitability for sustainability through an untested automation equipment and a serum free cell media.

Ithaca, Ny

Generated protocol and controlled experiment for researching methods of expediting and validating means of coliform and E. coli detection within EPA detection limits. Researched and pitched various ideas for potential solutions and conducted these experiments/presented data. Managed facilities and maintained bacteriology equipment and cultures.

Ithaca, New York, United States

Performed Minimum Inhibition Concentration (MIC) Assay for pathogenic bacteria viability under antibacterial agents found in Cystic Fibrosis patient cultures determined using Fluorescence readings after bacterial culturing and antibacterial testing.Responsible for culturing and maintaining different bacterial cultures.

Master'S Degree, Biomedical/Medical Engineering

Bachelor'S Degree, Biomedical/Medical Engineering