Director, Functional Genomics
Current
Jun 2024 - Present
AeroLeads people directory · profile
Nicole S. Persky Email & Phone Number
Director, Functional Genomics
at
Constantiam Biosciences
LinkedIn matched
✓ Verified July 2026
3 data sources
Profile completeness 86%
Current company
Role
Director, Functional Genomics
Location
Greater Boston, United States
Who is Nicole S. Persky? Overview
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Nicole S. Persky is listed as Director, Functional Genomics at Constantiam Biosciences, based in Greater Boston, United States. AeroLeads shows a matched LinkedIn profile for Nicole S. Persky.
Nicole S. Persky previously worked as Sr. Research Scientist at Aera Therapeutics and Research Scientist II, Genetic Perturbation Platform at Broad Institute Of Mit And Harvard. Nicole S. Persky holds Postdoctoral Fellow/American Cancer Society Postdoctoral Fellow, Structural Biology, Lab Of Nikola Pavletich, Phd from Memorial Sloan Kettering Cancer Center.
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Constantiam Biosciences
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Profile bio
About Nicole S. Persky
Results-driven researcher with a Ph.D. in Biophysics, showcasing a rich background in functional genomics, protein engineering, precision medicine, and deep mutational scanning screens. Spearheads assay development, design and execution of screens, and establishes training and robust best practices frameworks for pooled screening. Numerous publications in high-impact journals addressing critical aspects of cancer biology, DNA repair mechanisms, and therapeutic target identification. Dr. Persky has also been actively involved in mentorship, managing, and teaching. Highly experienced in cross-discipline collaboration, works well under pressure, excellent interpersonal skills.
Current workplace
Nicole S. Persky's current company
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8 roles
Nicole S. Persky work experience
A career timeline built from the work history available for this profile.
Sr. Research Scientist
Focus: Developing and executing functional genomics and deep mutational scanning screens for proprietary proteins. As part of this, led assay development for growth and flow cytometry assays, designed and performed screens, and established training and documentation frameworks for pooled screening within the company.
Sep 2022 - Jan 2024
Research Scientist Ii, Genetic Perturbation Platform
Focus: Deep Mutational Scanning, CRISPR, ORF, and Base Editing Screens, specializing in the design and interpretation of pooled mutagenesis screens for therapeutic targets. Collaborated and consulted on ~79 screening projects. Optimized screening strategy, troubleshooting, interpretation and quality controls. Initiated, designed and wrote a grant for experiments to pressure test new screening technologies. Led a monthly Screeners Meeting where collaborators could share their experiences with screening. Group: Genetic Perturbation Platform, Directed by David Root, PhD.
May 2019 - Sep 2022
Research Scientist I, Cancer Program
Focus: Identification of common ATP-competitive Inhibitor Resistance Sites in Kinases utilizing Deep Mutational Scanning pooled screening. Hypothesized, designed and tested comparative mutagenesis functional assays to identify drug resistance in cancer therapies for ultimate prevention. Supported multiple other Cancer Program projects as part of a highly collaborative team. Served as a committee member for the “Innovators in Cancer Research” seminar seriesGroup: Cancer Program, Group of Cory Johannessen, PhD.
Nov 2015 - May 2019
Postdoctoral Fellow/American Cancer Society Postdoctoral Fellow
Focus: Mechanisms of Fanconi Anemia Proteins in Crosslinked DNA Damage Repair. Purification, crystallization, biochemistry and interpretation of protein complexes of FancI and FancD2 in the presence of various types of DNA. Initiated work on Fanconi Anemia Mono-ubiquitination Complex from zebrafish and human constructs. Synthesized and purified covalently crosslinked DNA using click-chemistry for use in structural and biochemical experiments for Fanconi Anemia proteins and the Fan1 exonuclease. Executed skilled protein production from Bacteria, Insect, and Mammalian cell culturesGroup: Structural Biology Department, Lab of Nikola Pavletich, PhD
Jul 2009 - Jul 2015
Phd Student
Focus: Biochemistry of the DNA Replication and Nutritional Stress Response Protein ObgE. Purified untagged proteins, undertook GTPase assays, (p)ppGpp binding assays, and cell death assays with DNA damaging agents. Additionally used quantitative microscopy to follow DNA replication in wild type and mutant cells.Group: Biophysics and Biology Departments, Lab of Susan Lovett, PhD.
Aug 2003 - Jun 2009
Laboratory Technician
Focus: Sequencing BRCA2 and FANCD2 Mutations in Fanconi Anemia Patients.Group: Molecular Diagnostics Laboratory, Lab of Edward Fox, PhD.
Sep 2001 - Jul 2003
Undergraduate Researcher
Focus: Copper-Pyrazine Compounds and Mn-12 thin film synthesis.Group: Chemistry Department, Lab of Sarah Stoll, PhD
Sep 1998 - May 2001
3 education records
Nicole S. Persky education
Postdoctoral Fellow/American Cancer Society Postdoctoral Fellow, Structural Biology, Lab Of Nikola Pavletich, Phd
Memorial Sloan Kettering Cancer Center
Doctor Of Philosophy, Phd, Biophysics/Biology, Lab Of Susan Lovett, Phd
Bachelor'S Degree, Chemistry With Honors, Lab Of Sarah Stoll, Phd.
FAQ
Frequently asked questions about Nicole S. Persky
Quick answers generated from the profile data available on this page.
What company does Nicole S. Persky work for?
Nicole S. Persky works for Constantiam Biosciences.
What is Nicole S. Persky's role at Constantiam Biosciences?
Nicole S. Persky is listed as Director, Functional Genomics at Constantiam Biosciences.
Where is Nicole S. Persky based?
Nicole S. Persky is based in Greater Boston, United States while working with Constantiam Biosciences.
What companies has Nicole S. Persky worked for?
Nicole S. Persky has worked for Constantiam Biosciences, Aera Therapeutics, Broad Institute Of Mit And Harvard, Memorial Sloan Kettering Cancer Center, and Brandeis University.
How can I contact Nicole S. Persky?
You can use AeroLeads to view verified contact signals for Nicole S. Persky at Constantiam Biosciences, including work email, phone, and LinkedIn data when available.
What schools did Nicole S. Persky attend?
Nicole S. Persky holds Postdoctoral Fellow/American Cancer Society Postdoctoral Fellow, Structural Biology, Lab Of Nikola Pavletich, Phd from Memorial Sloan Kettering Cancer Center.
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