Ali Nikdel, Phd is a VP of Bioprocess Engineering at n!Biomachines. They is proficient in French and English. Colleagues describe them as "I first met and worked with Ali during my time University of Toronto. As colleagues in the same research laboratory, we collaborated on many projects while studying fungal secondary metabolites. It is truly a pleasure to work alongside Ali. He is not afraid of a challenge and is always bringing fresh, creative and innovative ideas to the table. I am constantly impressed with his ability to develop research questions in response to solvable problems and to frame his science in meaningful, impactful ways. Additionally, Ali is phenomenal at not only envisioning the end goal and impact of his science, but is constantly learning, exploring ideas and networking to be able to see a project through and make this end goal a reality. I whole heartedly recommend Ali for being a hardworking, innovative and easy to work with colleague.", "I had the chance to work with Ali at the same university while he was doing his PhD research. Ali was a very nice, respectful, and helpful person to work with. I recommend him to any group seeking his technical skills.", and "Ali knows Biopharma very well.I have worked for two months with him at SD8.He is a professional in Bioprocess Technology. He has an immense energy and ability to get stuff done! He's always with new ideas and not afraid to try them. He is very responsible and attentive."
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Vp Of Bioprocess EngineeringN!Biomachines May 2024 - Present -
Director Of InnovationN!Biomachines Mar 2024 - May 2024 -
Head Of BioprocessingThe Cultivated B Jun 2023 - May 2024Heidelberg, Baden-Württemberg, De -
Director Of InnovationThe Cultivated B Aug 2023 - Mar 2024Heidelberg, Baden-Württemberg, De -
Process Development ManagerStemcell Technologies May 2023 - Jun 2023Vancouver, Bc, Ca -
Lead Scientist 3Ccrm Jun 2022 - Aug 2022Toronto, Ontario, CaWorking as a Bioprocess Engineer/ Scientist developing processes for cell and gene therapy. -
Specialist For Process And ProductSanofi Nov 2020 - Jun 2022Paris, France, FrI worked as the cP Upstream SPP at Sanofi Pasteur. I was considered the know-how guardian of Upstream Component Pertussis(cP). Provided scientific guidance and performed data analysis for the continuous improvement of the process, deviation root cause analysis, and decision making. Provided support to different groups such as Regulatory affairs(RA), QOOQ, and QOVS. Contributed to CAPAs CCRs, and wrote scientific reports, provided support for the Health Authorities' inspections. I also contributed to the knowledge transfer group. -
Postdoctoral AssociateUniversity Of Toronto Jun 2018 - Nov 2020Toronto, Ontario, CaAs a postdoctoral associate working at Prof. Justin Nodwell's lab worked on synthetic biology and engineering of microorganisms(fungi and yeast mainly) for producing secondary metabolites. As a Bioengineer with prior experience in process development and optimization here, I gained experience in Synthetic(and molecular) biology areas, techniques like gene assembly using Gibson assembly, Infusion assembly, cloning, NEBuilder, and many more. -
Fermentation SupervisorToronto Research Chemicals Sep 2017 - Nov 2020Toronto, Ontario, CaJoined TRC in September 2017 on a mission to start the Biolab for fermentation-based products. Achievements:• Obtained Risk Group 2 Pathogen and Toxin Licence from The Public Health Agency of Canada (PHAC)• Performed a business studies on the fermentation products• Identified the requirement for the fermentation lab to meet the requirement of the process and CL2, including the layout design, and equipment• Prepared the SOPs for working in CL2 facility• Developed fermentation products from bench scale to large scale• Negotiations on the large-scale production scale up with NRC and other facilities in Canada -
Research AssistantUniversity Of Waterloo Nov 2012 - May 2018Waterloo, Ontario, CaI did my Ph.D. under the supervision of Professor Hector Budman focusing on Systems Biology and Bioprocess DevelopmentKey achievements:• Set up a bioreactor lab with a minimal budget, designing and building some of the required equipment • Developed a high cell density ATF perfusion process for CHO cells producing Monoclonal antibodies(mAbs)• Initiated collaboration with MilliporeSigma on the process and media optimization that is continuing • Developed two algorithms for identifying the objective function(s) and constraint in developing metabolic models (Flux Balance Analysis type of models) -
Bioprocess Research EngineerShanghai Jiao Tong University Oct 2011 - Nov 2012上海, Shanghai, CnI was a guest researcher at Shanghai Jiao Tong University while working in a university-based CRO company developing a cell culture process for producing biopharmaceuticals and vaccines.I was granted a scholarship to do my Ph.D. in SJTU.Key achievements:• Bioprocess development, optimization, and scale-up of Vero cells (in perfusion mode) for manufacturing viral vaccines• Developed a successful international technology transfer for a new biologic product -
Bioprocess Engineer,Head Of Upstream DevelopmentSaman Daroo 8 Jul 2009 - Sep 2011I was hired as one of the early technical teams at Saman. As in many new companies and startups (spin offs) I wore several hats. Some of my achievements:• Designing a new lab and managing the project on preparing a GMP pilot plant procurement of the required equipment• Technology transfer and bioprocess development for producing recombinant protein Antihemophilic factor VIII (rAhFVIII)- Mainly upstream but also downstream• Preparing business studies for the production facility and co-writing a proposal that approved for 2-million-dollar grant from Ministry of Health and another 20-Million-dollar loan from the bank• Involved in building the team • Worked in with the technical team and the project manager for designing the building, HVACs and design and procurement of large-scale bioprocess equipment
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Bioprocess Engineer,Research AssistantInstitut Pasteur Nov 2006 - Jul 2009Paris, FrI started as a volunteer and intern working at Pasteur Institute during my master's degree I was hired there as a bioprocess engineer. I did my master's thesis on the optimization of L-lysine production using Corynebacterium Glutamicum by implementing the Design of Experiment (DoE) methods. After graduation worked in the Pilot Biotechnology department as a researcher and in the production site for producing Hepatitis B virus surface antigen (HBsAg) (Hepatitis B vaccine).Key achievements:• Increased L-Lysine production at least 5 times by implementing Design of experiments (DoE) methods optimizing the media• Gained experience working on the vaccine production GMP facility working with 400-liter fermenters and acquainted with the large-scale purification of vaccines using centrifuges, ultrafiltration, column chromatography, and filtration systems
Ali Nikdel, Phd Education Details
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University Of WaterlooChemical Engineering -
National Organization For Development Of Exceptional Talents (Sampad)
Frequently Asked Questions about Ali Nikdel, Phd
What company does Ali Nikdel, Phd work for?
Ali Nikdel, Phd works for N!biomachines
What is Ali Nikdel, Phd's role at the current company?
Ali Nikdel, Phd's current role is VP of Bioprocess Engineering.
What schools did Ali Nikdel, Phd attend?
Ali Nikdel, Phd attended University Of Waterloo, National Organization For Development Of Exceptional Talents (Sampad).
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