I am a neurobiologist with extensive experience in leading innovative and collaborative research projects. My research is focusing on understanding mechanisms underlying neurodegenerative diseases, with a special focus on amyloid peptides, protein homeostasis and vasculature. I have seven years of experience studying the impact of amyloid peptides on brain vascular cells in neurodegenerative diseases using cell cultures, human/rodent tissue and human biological fluids. Moreover, I have two years experience investigating selective vulnerability in neurodegenerative diseases in relation to protein homeostasis and lysosomes and two years experience working with biomarkers using in vivo models of Alzheimer's disease. My productivity is reflected in my excellent track record of cutting-edge research, with 15 publications in well-renowned journals.Technical skills: • Biomarker analysis (CSF/blood/tissue) • Immunoassays (RT-qPCR, commercial ELISAs, development and optimisation of in-house ELISAs, Mesoscale) • In vivo (FELASA qualification), ex vivo and in vitro models of Alzheimer's disease • Isolation and culturing of primary human cells (skin fibroblasts, brain cells (pericytes, iNeurons, endothelial cells, astrocytes, neurons) and several cell lines (HEK293, SH-SY5Y)) • Protein biochemistry (immunocytochemistry, western blot, protein/ligand binding assays, enzyme kinetics) • Histology, processing of human/rodent tissue (sectioning, preparation, immunohistological stainings) • Imaging (wide field-, fluorescence- and confocal microscopy) • Basic cellular and molecular biology techniques (PCR, cloning, plasmid purification)