Niraj Patel, Ms, Phd personal email
- Valid
As an experienced neuroscientist with over 13 years of experience, I specialize in translating preclinical research into clinical applications. My focus is on developing advanced models and analytical tools for brain disease therapeutics. My expertise includes stem cell therapeutic development, project and experimental design, and In vitro / In vivo disease model development. I also possess skills in In vitro/ In vivo electrophysiology, molecular, cellular, and physiological assay development, and advanced analytical proficiency in Python, R, and other statistical tools. Additionally, I have strong writing, presentation, and communication skills.Aside from my scientific background, I have a strong foundation in scientific communication and strategic decision-making. This has led to the authorship of 6+ scientific articles and presentations at 50+ conferences, as well as securing over $450K in lab grants and scholarships.I collaborate effectively with interdisciplinary teams across academia, CROs, and industry. My organizational skills and attention to detail have driven successful leadership and key milestones. I am committed to continuous learning and staying updated in research and development.CORE EXPERTISE:Research and Development:- Developed diverse cell-based assays and conducted impactful drug screenings.- Created iPSC-based neuronal models.- Proficient in immuno-assays, FACS, cell transplantation, protein, and RNA analysis.- Conducted phase imaging, electrophysiology, and calcium imaging to study neuronal behavior.- Developed image processing pipelines using Caiman, Jupyter Notebooks, and Python.Project Management:- Proficient in project definition and research planning.- Experienced in budgeting and securing funding.- Designed project timelines and research methodologies.- Effective in prioritizing tasks and adapting to changing priorities.- Skilled in report writing and publication.Interpersonal Skills:- Efficiently manage multiple tasks in dynamic environments.- Excel in communication and conflict resolution.- Adapt quickly to fast-paced settings with shifting priorities.Personal Growth:Beyond my professional pursuits, I am dedicated to personal growth through meditation, walking, and continuous learning.Let’s connect and explore how we can collaborate to make a significant impact! 🙏
-
Scientist-IiRevival BioBoston, Ma, Us
-
Doctoral ResearcherFondation Cervo May 2017 - PresentQuebec City, Quebec, CanadaDoctoral Project: Innovative Brain Disease Modeling using Human-induced pluripotent Stem Cells (iPSCs) Derived Cortical Neural Cultures and Multimodal Digital Holographic Microscopy with a Spotlight on NMDA Receptors Activity.Sub-projects:1) Standardization and optimization of iPSCs-derived cortical neural culture, which forms an active and functional network in vitro.2) Development of a methodological approach for long-term Ca2+ imaging of neurons within mixed neural culture… Show more Doctoral Project: Innovative Brain Disease Modeling using Human-induced pluripotent Stem Cells (iPSCs) Derived Cortical Neural Cultures and Multimodal Digital Holographic Microscopy with a Spotlight on NMDA Receptors Activity.Sub-projects:1) Standardization and optimization of iPSCs-derived cortical neural culture, which forms an active and functional network in vitro.2) Development of a methodological approach for long-term Ca2+ imaging of neurons within mixed neural culture derived from human iPSCs using GECI tools.3) Non-invasive assessment of neuronal activity by measuring water movement in neurons elicited by glutamate ionotropic receptors with multimodal digital holographic microscopy (DHM).Highlights of key findings:• Utilized a multimodal digital holographic microscope (M-DHM), a non-invasive and high-resolution live cell imaging technique, to assess NMDA receptor activity during neurodifferentiation.• Developed and optimized a standardized protocol for differentiating human induced pluripotent stem cells (iPSCs) into mixed cortical neuronal culture.• Characterized the iPSC-derived mixed cortical neurons culture using fluorescence-activated cell sorting (FACS), Immunocytochemistry (ICC), Western blot (WB), quantitative-PCR, and Whole patch-clamp techniques to ensure accurate representation of neuronal properties.• Demonstrated and established the transmembrane water fluxes (TWFs) in iPSCs-neurons and the foundation for a label-free imaging assay using iPSC-derived human neurons in vitro, with potential applications in understanding the pathophysiology of psychiatric disorders. Show less -
Research TraineeBoston University School Of Medicine Aug 2024 - Sep 2024Boston, Massachusetts, United StatesProject: In Vitro and In Vivo Studies on Neural Circuits and Microglia: Unraveling the Role of Reelin-APOE Pathways in Neurodegenerative Diseases, with a Focus on Alzheimer's Using Rodent and Human Models.Leading in vitro and in vivo studies on Alzheimer’s disease and develope therapeutic interventions using human iPSCs and rodent models, contributing to potential clinical applications.Managing project scopes, goals, deliverables, and timelines. Monitoring regularly project… Show more Project: In Vitro and In Vivo Studies on Neural Circuits and Microglia: Unraveling the Role of Reelin-APOE Pathways in Neurodegenerative Diseases, with a Focus on Alzheimer's Using Rodent and Human Models.Leading in vitro and in vivo studies on Alzheimer’s disease and develope therapeutic interventions using human iPSCs and rodent models, contributing to potential clinical applications.Managing project scopes, goals, deliverables, and timelines. Monitoring regularly project report progress against milestones and budget, ensuring alignment and timely completion. Show less -
Research AssistantUniversité De Montréal Jul 2016 - Apr 2017Montreal, Canada AreaWorked on a project entitled; To investigate the treatment of degenerative macular disease by using stem cell therapy.• Generation, development and maintenance of human-induced pluripotent stem cells (iPSCs) In-vitro.• Differentiation of iPSCs cells into Rod and Cone cells in In-vitro 2D culture for Pharmacological tests.• Maintained various cell lines (ESCs, feeder cells, NIH3T3 and H293T) to conduct experiments.• Performed reverse transcription-polymerase chain… Show more Worked on a project entitled; To investigate the treatment of degenerative macular disease by using stem cell therapy.• Generation, development and maintenance of human-induced pluripotent stem cells (iPSCs) In-vitro.• Differentiation of iPSCs cells into Rod and Cone cells in In-vitro 2D culture for Pharmacological tests.• Maintained various cell lines (ESCs, feeder cells, NIH3T3 and H293T) to conduct experiments.• Performed reverse transcription-polymerase chain reaction (RT-PCR) for RNA analysis.• Immunocytochemistry (ICC) and western blot (WB) for protein analysis.• Image processing and data analysis to communicate results to the scientific community.• Collaborate with industry to apply the results of research and develop new techniques and product development. Show less -
Research AssistantIndian Institute Of Science Oct 2014 - Jun 2016BangaloreProject-1; Investigating the mechanisms for early diagnosis and treatment of Alzheimer’s disease using induced pluripotent stem cells (iPSCs) derived neurons.• I developed in-vitro cortical neuron culture from human-induced pluripotent stem cells, which were derived from blood cells.• Standardise in-vitro AD model for pharmacological screening and to understand the mechanisms of beta-amyloid plaques accumulation in sporadic AD.Project-2; Studying the role of… Show more Project-1; Investigating the mechanisms for early diagnosis and treatment of Alzheimer’s disease using induced pluripotent stem cells (iPSCs) derived neurons.• I developed in-vitro cortical neuron culture from human-induced pluripotent stem cells, which were derived from blood cells.• Standardise in-vitro AD model for pharmacological screening and to understand the mechanisms of beta-amyloid plaques accumulation in sporadic AD.Project-2; Studying the role of SCL/TAL1 interrupting locus (STIL) in autosomal recessive primary microcephaly (MCPH) using mouse models.• The project involves extensive work using a variety of approaches such as electroporation (NEPAGENE) to transfect human STIL gene to in vitro cultured cortical embryonic neurons and in vivo embryonic transfection, molecular biological techniques, and confocal microscopy.• This study showed an altered neuronal morphology following transfection suggestive of morphological abnormalities as observed in MCPH patients. Show less -
Graduate Research And Teaching AssistantIndian Institute Of Science (Iisc) Feb 2016 - Apr 2016Bengaluru, KarnatakaI gave Neurobiology practical training to 40+ undergraduate (UG) and Post-graduate (PG) students. The training was on;• Mice handling, breeding and maintenance.• Mice pub embryo isolation at a different time point.• Maintenance and storage of stem cells. • Cortical neuron differentiation and maintaining cell cultures.• Immunocytochemistry and microscopy imaging and analysis.• Writing reports and preparing presentations and taking exams.
-
Research Project AssistantBio Medical Technology Wing Sctimst Sep 2012 - Jun 2014Trivandrum,Kerala, IndiaProject-1; The effects of maternal sleep deprivation on cognition in the offspring in an animal model,Project -2; The impact of acute maternal total sleep deprivation (TSD) at the third trimester of pregnancy in the rat model,• I performed stereotactic brain surgery on 100+ Wister rat to implant the electrode to study brain rhythm.• Record Ultrasonic Vocalization (USVs) from rat pups and analyzed them with Avisoft and SAS-Lab.• Performed EEG, EMG and EOG… Show more Project-1; The effects of maternal sleep deprivation on cognition in the offspring in an animal model,Project -2; The impact of acute maternal total sleep deprivation (TSD) at the third trimester of pregnancy in the rat model,• I performed stereotactic brain surgery on 100+ Wister rat to implant the electrode to study brain rhythm.• Record Ultrasonic Vocalization (USVs) from rat pups and analyzed them with Avisoft and SAS-Lab.• Performed EEG, EMG and EOG recordings and analysis by BioPac system (model 150) software and Data Sciences International (DSI) telemetric system.• Cognitive behavior analyzed using the Any-Maze system, plus maze and open field test for anxiety.• Results showed that maternal REM sleep deprivation significantly modulates ultrasonic vocalizations of the neonates and acute maternal total sleep deprivation (TSD) increased the anxiety and risk-taking behavior in rats. Show less -
Quality Control AnalystIntas Pharmaceuticals Mar 2012 - Sep 2012Ahmedabad, Gujarat, India• Support R&D and product Supply and assist in project/technology/method transfer in the QA/QC department.• Review & approve batch records, documentation for records, product validation and stability testing at different time points and conditions using multiple laboratory tools.• R&D supports the compliant and timely closure of all project work requiring Quality Assurance approval.• Document review & approval, such as method validations, manufacturing records and… Show more • Support R&D and product Supply and assist in project/technology/method transfer in the QA/QC department.• Review & approve batch records, documentation for records, product validation and stability testing at different time points and conditions using multiple laboratory tools.• R&D supports the compliant and timely closure of all project work requiring Quality Assurance approval.• Document review & approval, such as method validations, manufacturing records and Standard Operating procedures (SOPs) development.• Maintenance of material safety data sheet (MSDS) and product data sheet (PDS) information for the company products and prepare technical reports.• Participate in good laboratory practice (GLP) and good manufacturing practice (GMP) training program as a part of job documentation training for R&D personnel.• Performed other duties as required or necessary. Show less -
Research AssociateVivo Bio Tech Ltd. Nov 2011 - Feb 2012Hyderabad, Telangana, IndiaProject-1;Inflammatory study on Sprague Dawley (SD) rats; an arthritis model for drug development and screening.• Regularly exercises technical discretion in design, execution and interpretation of experiments that contribute to project goals.• Involved in teamwork, provide guidance to less senior personnel and providing solutions to problems associated with specific projects.• Prepares technical reports, summaries, protocols and quantitative analyses and discusses… Show more Project-1;Inflammatory study on Sprague Dawley (SD) rats; an arthritis model for drug development and screening.• Regularly exercises technical discretion in design, execution and interpretation of experiments that contribute to project goals.• Involved in teamwork, provide guidance to less senior personnel and providing solutions to problems associated with specific projects.• Prepares technical reports, summaries, protocols and quantitative analyses and discusses the outcomes with supervisors and project team members. Show less -
Quality Control AnalystActive Pharma Lab. Oct 2010 - Aug 2011Hyderabad, Telangana, India• Make documents to collect the raw material form production department to perform tests,• Calibration of wet analysis instrument (KF titration, LOD, Sulphated ash etc.)• High-performance liquid chromatography (HPLC) analysis,• Gas Chromatography (GC) analysis, • Preparation of datasheets and so on.
-
Science TeacherKrishnaveni Talent School - India Jul 2010 - Jun 2011Hyderabad Area, India• A High School Biology Teacher who understands the very best ways to get students interested in biology.• Develop lesson plans and themes in line with curriculum objectives specific to teaching biology subjects.• Instruct students through lectures, discussions, and demonstrations. • Prepare, administer, and grade tests and assignments to evaluate student progress. -
Office Managing PartnerMaa Sharda Medical Agency Jan 2007 - Jun 2008Rewa Area, India• Responsible for handling questions, concerns and special requests from clients.• Demonstrate professionalism at all times; on the phone, through email, and during meetings.• Maintenance of pharmacy stock, Handling customer prescription and day-to-day operations of retail sales.• Maintain a clean and organized workplace.• Documentation of operation performed on a lot and computer data entry.
Niraj Patel, Ms, Phd Skills
Niraj Patel, Ms, Phd Education Details
-
Neurosciences -
Jiwaji University, Gwalior, Madhya Pradesh, IndiaNeuroscience -
Barkatullah University, Bhopal, Madhya PradeshBiotechnology
Frequently Asked Questions about Niraj Patel, Ms, Phd
What company does Niraj Patel, Ms, Phd work for?
Niraj Patel, Ms, Phd works for Revival Bio
What is Niraj Patel, Ms, Phd's role at the current company?
Niraj Patel, Ms, Phd's current role is Scientist-II.
What is Niraj Patel, Ms, Phd's email address?
Niraj Patel, Ms, Phd's email address is ni****@****ail.com
What schools did Niraj Patel, Ms, Phd attend?
Niraj Patel, Ms, Phd attended Université Laval, Jiwaji University, Gwalior, Madhya Pradesh, India, Barkatullah University, Bhopal, Madhya Pradesh.
What are some of Niraj Patel, Ms, Phd's interests?
Niraj Patel, Ms, Phd has interest in Education, Environment, Science And Technology, Human Rights, Animal Welfare, Health.
What skills is Niraj Patel, Ms, Phd known for?
Niraj Patel, Ms, Phd has skills like Hplc, Biotechnology, Pharmacology, Cell Culture, Protein Chemistry, Animal Models, Biochemistry, Immunohistochemistry, Molecular Biology, Rt Pcr, Neuroscience, Elisa.
Free Chrome Extension
Find emails, phones & company data instantly
Aero Online
Your AI prospecting assistant
Select data to include:
0 records × $0.02 per record
Download 750 million emails and 100 million phone numbers
Access emails and phone numbers of over 750 million business users. Instantly download verified profiles using 20+ filters, including location, job title, company, function, and industry.
Start your free trial