Nishant Verma Email & Phone Number

San Francisco Bay Area

I am on the Science & Technology team. We manage a growing research portfolio to uncover the mechanisms of action of our clinical stage chronic pain therapy. We also lead electrode development and safety testing to inject the large amounts of charge required for ULF therapy.- Designed and initiated 2 study protocols for a preclinical rodent and sheep study at CRO facilities.- Designed and managed 4 preclinical studies with academic collaborators.- Designed electrochemical materials safety characterization tests for high charge capacity neurostimulation electrodes.- Developed novel bench model to study electrode stimulation related phenomena.- Investigated and root caused electrode stimulation related electrochemistry phenomena.- Analyzed clinical and preclinical data using Python tools and statistics.- Designed clinical study to investigate mechanisms of action of ULF therapy.- Mentored 1 summer intern.- Developed pipeline applications for platform neural inhibition technology. Filed 15 invention disclosures.- Worked with clinical team to define patient programming algorithms.- Delivered podium presentation at International Neuromodulation Society 2024 - Led SBIR NIH submission

Greater Minneapolis-St. Paul Area

NeuraWorx is commercializing technology I developed during my PhD to increase brain waste clearance. The technology has clinical implications towards treating Alzheimer's disease.- Designed, fabricated, and tested biphasic current-controlled stimulator to deliver temporally patterned waveform in a small form factor. Wrote associated documentation.- Hacked a consumer product to test temporal patterning of natural neural stimuli (non electrical stimuli).

Madison, Wisconsin, United States

- Led 20 large-animal studies (electrophysiology, MRI, PET) and performed data analysis and plotting in Python- Developed minimally invasive Injectrode using COMSOL electroquasistatic modeling- Systematically reviewed clinical trials in non-invasive neuromodulation- 3 minute thesis (3MT) 1st position at UW-Madison finals- Mentored and managed 7 undergraduates- Evoked compound action potentials (ECAPs) electrophysiology recordings for direct measurements of on- and off-target neural engagement and closed-loop neuromodulation- Electrochemical characterization of electrodes- Trigeminal nerve stimulation to restore glymphatic clearance by modulating cerebral blood flow dynamics with applications to Alzheimer’s disease- Worked with MRI and PET imaging concurrent with electrical stimulation

Atlanta, Georgia, United States

- Developed commercial strategy for reflex training therapy, based on Dr. Jon Wolpaw's research, through market research- Led applications exploration for platform technology by evaluating market size, IP landscape, reimbursement, clinical data and informed by KOL interviews

Plano, Texas, United States

Neuromodulation Applied Research team- Conducted pre-clinical swine studies for spinal cord and peripheral nerve stimulation including study design, surgery, and data analysis- Performed new indication R&D for Dorsal root ganglion (DRG) stimulation- Filed 4 invention disclosures and compiled 12 technical reports- Named inventor on 4 filed US patents- Iterated through product-market fit concepting guided by customer discovery interviews- Developed hardware design targets working cross-functionally with IC design, Advanced Development, and external KOLs

Rice University

In Dr. Jacob Robinson's lab. Research on magnetoelectric devices with application to wireless neuromodulation. The new device could enhance Peripheral Nerve Stimulation (PNS) and other small form-factor applications deep in the body. Now under commercial development by Motif Neurotech.WO2020206332A1, “Magnetoelectric Data and Power to Miniature Biodevices with Tunable Amplitude and Waveform”

Houston, Texas Area

Allotrope is bringing to market smooth muscle stimulation technology. I led the development and execution of protocols for two porcine model animal studies to define the waveform profiles for StimSite. In addition, I designed the alpha prototype electrical circuit, PCB, and firmware to charge a capacitor using a DCDC converter and then discharge the energy into intraabdominal tissue to illicit smooth muscle contraction. StimSite has received FDA 510k clearance and is now in operating rooms. Allotrope has been acquired by Northgate Technologies Inc, making Allotrope the first medtech startup to be founded and exited in Houston.I then worked on Allotrope's secondary product - an ingestible bioelectronic pill for post-operative recovery.US11,129,990B2, “Delivery System for Intracorporeal Smooth Muscle Stimulation”

San Francisco Bay Area

Cala Health is working on non-invasive neurostimulation for essential tremor. I conducted LTSpice simulations to understand circuit behavior and variation. I also investigated circuit topology and tuning to increase battery life of the wearable. In addition, I investigated our proprietary dry electrodes for alternative applications. In the process, learning about the fundamentals of neurostimulation, autonomic nervous activity, and skin-electrode interfaces. Lastly, I evaluated the IP landscape we are operating in to determine blue and red spaces for future development.

Houston, Texas Area

LivaNova sells a neuromodulation device to provide therapy to epilepsy patients. I worked on the next generation Bluetooth (BLE) enabled implant. This involved evaluating and modeling BLE protocols for implementation in low power medical implants. I also characterized leading BLE SoCs on the market. After going through concept selection for a BLE chip I tested and debugged next generation BLE implantable pulse generator (IPG) prototypes. I also worked to troubleshot E&M phenomena in the current inductive communication system of the IPG.

Singapore

I designed and commercialized EBlocks, an educational kit that visually emulates real circuit design principles while providing an accessible interface for K-12 students to learn about electronics. Sold the product rights to Singapore Science Center Holdings.

Singapore

I presented my work on the photoacoustic theory and won 1st position at the world finals of the research conference.

Doctor Of Philosophy - Phd, Biomedical/Medical Engineering

Master Of Science - Ms, Biomedical/Medical Engineering

Bachelor Of Science - Bs, Bioengineering And Biomedical Engineering

Activities and Societies: Design For America, Rice university cycling and triathlon club (RUCT)Trustee Distinguished Scholar

High School, International Baccalaureate