Development of an intranasal delivery system of an antipsychotic agent for the acute treatment of schizophrenia and other psychotic conditions. • Developed HPLC based analytical method for model drug and validated the developed method.• Characterized the physicochemical properties of drug such as solubility, partition coefficient and stability in various pharmaceutical vehicles and aqueous buffer systems for intranasal delivery.• Developed microemulsion formulations of model drug… Show more Development of an intranasal delivery system of an antipsychotic agent for the acute treatment of schizophrenia and other psychotic conditions. • Developed HPLC based analytical method for model drug and validated the developed method.• Characterized the physicochemical properties of drug such as solubility, partition coefficient and stability in various pharmaceutical vehicles and aqueous buffer systems for intranasal delivery.• Developed microemulsion formulations of model drug, characterized selected formulations, investigated physicochemical stability of microemulsion formulations and studied dose reproducibility of formulations using nasal spray devices for the proposed intranasal delivery system.• Investigated the in-vitro transmucosal permeability of drug candidate in various vehicles and formulations across rabbit nasal mucosa.• Investigated synthetic membrane to mimic biological membrane for the transmucosal permeation of model drug.• Evaluated the effect of essential amino acids individually and in-combination on blood glucose level.• Carry out measurement of powder characteristics such as compressibility/flow ability and powder blending as a proof of concept for further formulation development of solid dosage forms.• Mimic marketed dosage form such as coated tablet, syrup, suspension, emulsion, powder and cream.• Attend lectures and seminars on drug discovery and development, formulation development of various dosage forms, cGMP, cGCP, cGLP, active and inactive ingredients in pharmaceuticals, new drug delivery systems such as controlled release, liposome, nano-particle, dendrimer, ADME, and cosmetic. Show less

• Teaching undergraduate laboratory courses in general and organic chemistry courses.• Carrying out lecture series on organic chemistry laboratory experiments

• Perform analysis of pharmaceutical raw materials & finished products (tablets/ capsules/ liquids). • Execute microbial testing of raw materials, finished products and de-mineralized water used in the production as well as conduct antimicrobial assay of antibiotics.• Perform manufacturing processes of liquid and tablet formulations including preformulation study, optimization study and scale up.• Provides oversight, implementation, and technical insight on various production… Show more • Perform analysis of pharmaceutical raw materials & finished products (tablets/ capsules/ liquids). • Execute microbial testing of raw materials, finished products and de-mineralized water used in the production as well as conduct antimicrobial assay of antibiotics.• Perform manufacturing processes of liquid and tablet formulations including preformulation study, optimization study and scale up.• Provides oversight, implementation, and technical insight on various production projects to insure accurate, efficient, and timely delivery.• Investigates production challenges, identifies causes of problems or failures, suggests/ implements solutions, writes protocols for and reports of investigations.• Prepares technical documentation including optimization, validation and stability protocol as needed.• Establishes and leads efforts of verifying records of inventories for raw materials, laboratory supplies, drug supplies, equipment and their calibration, maintenance and operational procedures. Show less