Nishita Parnandi Email & Phone Number

United Kingdom

Boston

Ph.D. student in the Biological and Biomedical Sciences Program

Chennai Area, India

Studied the role of miRNA-7 in breast cancer. - Using bioinformatics, we initially predicted an 8-9 bp region in the 3'​ UTR of VDAC-1, conserved across species, to be a target site for miR-7. A breast carcinoma cell lysate panel was used to analyse the endogenous expression levels of VDAC-1. - Based on these results, we chose two cell lines for further.

Komaba, Tokyo

- Studied cardiac regeneration by analysing expression levels of genes in mice cardiomyocytes stressed under Transverse Aortic Constriction. - Results indicated that cardiomyocyte structural genes, cell cycle regulators and stress response genes are significantly correlated, suggesting their involvement as a network in cardiac regeneration.

Cambridge, United Kingdom

- Examined high confidence mutations in the sequences of H37Rv strain of Mycobacterium tuberculosis, as documented in CHOPIN, a database consisting of the structural models of the proteome of Mtb. - Using SDM and mCSM algorithms, the mutations were classified into neutral and deleterious on the basis of the difference in free energies of the wild type and.

Bengaluru Area, India

- Designed an algorithm to predict interacting domains in protein-protein interfaces for prediction and modelling of protein-protein complexes.