Nitin Khatri Email & Phone Number

Gurgaon, India

Experienced Research & Development and Regulatory Professional with over 5 years of expertise in the medical devices and stem cell-based therapeutic products. Proficient in independently handling the processing, characterization, and differentiation of adult and tissue-specific human mesenchymal stem cells (MSC), specifically derived from clinical-grade bone marrow, both in 2D cultures and within tissue-engineered scaffolds/hydrogels.Possessing 2 International Patents and a portfolio of… Show more Experienced Research & Development and Regulatory Professional with over 5 years of expertise in the medical devices and stem cell-based therapeutic products. Proficient in independently handling the processing, characterization, and differentiation of adult and tissue-specific human mesenchymal stem cells (MSC), specifically derived from clinical-grade bone marrow, both in 2D cultures and within tissue-engineered scaffolds/hydrogels.Possessing 2 International Patents and a portfolio of publications in esteemed international journals, my current focus involves pioneering work on an artificial skin substitute—a cutting-edge stem cell-impregnated scaffold designed for diabetic foot ulcers and venous leg ulcers. My role extends to overseeing the clinical trial for this innovative product as a Clinical Trial Monitoring Scientist at three sites in India.Apart from designing experiments in compliance with OECD/GLP and ISO guidelines, I play an integral role in the preparation and review of regulatory documents compliant with EU-MDR and USFDA. My dedication to advancing medical research is evident in both my practical contributions and my commitment to ensuring all processes adhere to the highest industry standards.ISO 13485| EU MDR 2017|ISO 17025| EUDAMEDTwo major projects that i worked upon are -a) "Differentiation of MSC's into insulin producing pancreatic islet cells" - Successfully developed pancreatic islet cells for which pre-clinical studies are ongoing.b) "Fabrication of novel biodegradable and biocompatible nerve guidance conduits for peripheral nerve injury"I have a strong background in project management and team collaboration, working with cross-functional teams to ensure that projects meet regulatory and safety standards. Show less

New Delhi Area, India

Employed as a Project Assistant II at CSIR-IGIB within Dr. Sivaprakash Ramalingam's Lab, my primary responsibilities centered around targeted genome engineering using CRISPR Cas9 technology. The core focus of our work was the rectification of diseased mutations in Sickle cell anemia and beta thalassemia patients. A noteworthy achievement was the successful integration of a 47bp mutation to intrinsically enhance the production of HPFH (Hereditary Persistence of Fetal Hemoglobin). This innovation… Show more Employed as a Project Assistant II at CSIR-IGIB within Dr. Sivaprakash Ramalingam's Lab, my primary responsibilities centered around targeted genome engineering using CRISPR Cas9 technology. The core focus of our work was the rectification of diseased mutations in Sickle cell anemia and beta thalassemia patients. A noteworthy achievement was the successful integration of a 47bp mutation to intrinsically enhance the production of HPFH (Hereditary Persistence of Fetal Hemoglobin). This innovation aimed to substantially reduce the number of transfusions required by individuals affected by these diseases. Show less

New Delhi Area, India

I worked at Advanced Genomics Institute and Laboratory Medicine as a BCIL research trainee where i was working with patient samples for the diagnosis of genetic disorders using techniques like FISH (Fluorescence in situ hybridization) and karyotyping.

Worked on project titled - "Study to investigate effect of caffeine on oxidative stress in 6-hydroxydopamine induced parkinson disease rodent model". Mastered techniques like stereotaxic rodent brain surgery, animal handling and training (rotarod and opto-varimax), various routes of drug administration, biochemical estimation and statistical data analysis.Our results showed that Caffeine indeed have neuroprotective effects on individuals. Behavioral and biochemical tests showed… Show more Worked on project titled - "Study to investigate effect of caffeine on oxidative stress in 6-hydroxydopamine induced parkinson disease rodent model". Mastered techniques like stereotaxic rodent brain surgery, animal handling and training (rotarod and opto-varimax), various routes of drug administration, biochemical estimation and statistical data analysis.Our results showed that Caffeine indeed have neuroprotective effects on individuals. Behavioral and biochemical tests showed significant development in rats administered with 6-OHDA neurotoxin when subsequently administered with caffeine treatment. Show less

Gurgaon, India

Master'S Degree, Biotechnology, 9.30

Activities and Societies: Organizing Committee "Avidadham" 2016 and 2017

Graduate, Biotechnology

Science (Medical)

Activities and Societies: cricket, debate team, choreography society