Nate Segraves

Nate Segraves Email and Phone Number

Associate Director @ Eyconis, Inc
Sunnyvale, CA, US
Nate Segraves's Location
Sunnyvale, California, United States, United States
Nate Segraves's Contact Details

Nate Segraves personal email

n/a
About Nate Segraves

Experienced Analytical chemist with experience is method development, transfer to CDMO/CLO, and QC management of contract organizations covering method familiarization, verification, validation and GMP testing for release and stability samples.Expertise in the characterization of small molecule (SM) API as well as impurities and degradants using LCMS, MS/MS, MSn, HR-MS, NMR, IR, etc. Also skilled in hyphenated technologies including LC-NMR-MS.Skilled in sample analysis and separation using analytical, semipreparative, and preparative chromatographic techniques: HPLC, Sephadex, Flash, and low pressure RP.Proficient in characterizing SM natural products using ESI-TOF-MS, UV-vis, and advanced 1D and 2D NMR techniques.Specialties: Purification of small molecules form mg to Kg scale using a variety of techniquesSmall Molecule structure characterization using spectrometric and spectroscopic methodsManagement of MS and NMR labs.

Nate Segraves's Current Company Details
Eyconis, Inc

Eyconis, Inc

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Associate Director
Sunnyvale, CA, US
Website:
eyconis.com
Employees:
35
Nate Segraves Work Experience Details
  • Eyconis, Inc
    Associate Director
    Eyconis, Inc
    Sunnyvale, Ca, Us
    View
  • Eyconis, Inc
    Associate Principal Scientist
    Eyconis, Inc Mar 2024 - Present
    Redwood City, California, United States
    Management of analytical method development to support early stage drug development. Oversee CDMO method familiarization and validation of methods for preparation of GLP tox to Phase 1 manufacturing of intermediates and drug substance. Subject matter expert for structure characterization of impurities and degradants in all stages of drug development.
    View
  • Segraves Workshop
    Chief Creative Officer (Cco)
    Segraves Workshop Oct 2020 - Present
    Sunnyvale, California, United States
    Self trained woodturner making handmade items like bowls, vases, etc. from reclaimed local trees.
  • Ascendis Pharma
    Associate Principal Scientist
    Ascendis Pharma Jan 2022 - Mar 2024
    Redwood City, California, United States
    View
  • Theravance Biopharma Us, Inc.
    Research Fellow (Associate Director)
    Theravance Biopharma Us, Inc. Feb 2017 - Aug 2021
    South San Francisco
    Head of Structure Characterization using NMR and LCMS.Analytical Lead of CMC teams supporting early stage development compounds.
    View
  • Genentech
    Scientist, Analytical And Structure Id
    Genentech Oct 2008 - Jan 2017
    San Francisco Bay Area
    Purification of Small Molecule Drug Substance (DS) and Drug Product (DP) impurities and degradants using low pressure chromatography and HPLC.Characterization of impurities and degradants by LCMS and NMR.Analytical lead of CMC teams developing analytical methods to support the production of DS and DP.
    View
  • Theravance Inc.
    Scientist
    Theravance Inc. Sep 2006 - Sep 2008
    Purification and structure eluicidation of drug impurities/degradants using prep HPLC, LCMS, NMR, etc.Analytical Development for GMP/GLP drug substance and drug product.Support of process R & D in the scale-up of API purification
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  • Kosan Biosciences
    Scientist, Process Sciences
    Kosan Biosciences Jul 2004 - Mar 2006
    Isolation of milligram to multi-gram quantities of polyketides from fermentation broth. Characterization of purified compounds using modern spectroscopic methods. Development of scalable purification processes for manufacturing of API under cGMP conditions.
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  • Envirodyne Incorporated
    Semivolatiles Technician
    Envirodyne Incorporated 1996 - 1998

Nate Segraves Skills

Hplc Chromatography Purification Analytical Chemistry Lc Ms Nmr Mass Spectrometry Characterization Ir High Performance Liquid Chromatography Technology Transfer Gmp Biotechnology Chemistry Organic Synthesis Drug Development Glp Drug Discovery Pharmaceutical Industry

Nate Segraves Education Details

Frequently Asked Questions about Nate Segraves

What company does Nate Segraves work for?

Nate Segraves works for Eyconis, Inc

What is Nate Segraves's role at the current company?

Nate Segraves's current role is Associate Director.

What is Nate Segraves's email address?

Nate Segraves's email address is ns****@****nce.com

What schools did Nate Segraves attend?

Nate Segraves attended University Of California, Santa Cruz, Florida Atlantic University, Lely High School.

What skills is Nate Segraves known for?

Nate Segraves has skills like Hplc, Chromatography, Purification, Analytical Chemistry, Lc Ms, Nmr, Mass Spectrometry, Characterization, Ir, High Performance Liquid Chromatography, Technology Transfer, Gmp.

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