- Delivery system design and development- Therapy development, physician training, case proctoring

Half Moon Medical is an early stage start-up out of The Foundry, the Bay Area’s premier medical device company incubator. Half Moon Medical is developing a novel catheter-delivered cardiac implant for patients with structural heart disease.

- Design and development of next-generation transcatheter mitral valve implant- Therapy development, clinical case support, imaging analysis

Twelve, Inc (acquired by Medtronic)

- Developed a first-in-class implantable cardiac device for treating tricuspid valve regurgitation- Implant design, IP development, rapid prototyping, material selection, clinical / anatomical research, animal studies, test method development, supplier management, design verification activities, clinical procedure development, physician training, and case proctoringSenior R&D Engineer: 2013 - 2015R&D Engineer II: 2012 - 2013Engineer I, Technical Development Rotational Program (2011 - 2012):Quality Engineering, Transcatheter Heart Valve Delivery Systems:- Drove manufacturing improvements and ran design verification testing on transapical cathetersR&D, Advanced Technology:- Generated IP, designed prototypes, and proved concept in-vivo for a novel cardiac implantableGlobal Marketing & Strategy, Surgical Heart Valves:- Built pricing, branding, and account targeting strategies for the China launch of two heart valvesR&D, Surgical Heart Valves:- Partnered with surgeons in designing new sewing ring mechanisms for an aortic valved conduit

- Designed early prototypes for a novel subclavian artery stent graft conduit on the Valiant Mona LSA; optimized for flexibility and fatigue life, and tested in subsequent chronic animal studies- Formulated a computational model for the radial strength of the Integrity coronary stent platform; utilized FEA and bench-top testing to validate the model and evaluate next-generation designs- Generated improved stent designs with thinner struts and potential to reduce late luminal loss

- Performed sales and marketing analysis for a major pharmaceutical company; designed sales force targeting, sizing, and deployment strategies for high-potential institutional accounts

- Screened gene candidates for involvement in tumor angiogenesis by viral RNAi delivery- Adapted various endothelial cell co-culture assays for use in high-throughput loss-of-function screens, and optimized conditions for accurate modeling of angiogenesis- Implemented novel image analysis techniques to improve descriptive power of angiogenesis models

- Designed antibody conjugates for selective delivery of carbon nanotubes in tumor cells- Coupled tumor-reactive monoclonal antibodies and chemotherapeutic agents to carbon nanotubes, and analyzed the effectiveness of using near-infrared radiation to release drugs