Oliver De Sa
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Oliver De Sa Email & Phone Number

Location: Toronto, Ontario, Canada 5 work roles 2 schools
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Role
Bioinformatician
Location
Toronto, Ontario, Canada
Company size

Who is Oliver De Sa? Overview

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Oliver De Sa is listed as Bioinformatician at Ontario Institute for Cancer Research, a company with 310 employees, based in Toronto, Ontario, Canada. AeroLeads shows a matched LinkedIn profile for Oliver De Sa.

Oliver De Sa previously worked as Bioinformatician at University Of Toronto and Masters Research Associate at University Of Toronto. Oliver De Sa holds Master Of Science - Ms, Immunology from University Of Toronto.

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Ontario Institute for Cancer Research

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Profile bio

About Oliver De Sa

As a bioinformatician in the Philpott Lab at the University of Toronto, I specialize in leveraging advanced computational tools to uncover insights from complex biological data. Over the past year, I’ve applied my expertise in next-generation sequencing (NGS), metagenomics, and machine learning to support research projects spanning oncology, immunology, and microbiome studies.My core strengths lie in analyzing large datasets, developing custom pipelines, and optimizing workflows for computational efficiency. I’m proficient in applying and developing custom bioinformatic tools, and have over 3 years of experience programming in Python and R. My experience extends to working with paired multi-omic datasets, including RNA-seq and Whole-Genome sequencing, where I’ve applied statistical models to investigate disease-associated patterns, gene expression, and microbial enzyme abundance.I’m passionate about using data-driven approaches to solve real-world biological challenges and continuously improving my skills in the rapidly evolving field of bioinformatics. Whether I’m working in an academic, clinical, or industry setting, I aim to contribute to projects that push the boundaries of human health research.

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Ontario Institute for Cancer Research
Ontario Institute For Cancer Research
Bioinformatician
toronto, ontario, canada
Website
Employees
310
AeroLeads page
5 roles

Oliver De Sa work experience

A career timeline built from the work history available for this profile.

Bioinformatician

Toronto, Ontario, Canada

  • Developed and optimized efficient, reproducible NGS data processing pipelines, including WGS and SC-RNA seq, in high-performance computing environments, quickly and accurately processing thousands of patient samples.
  • Processed and analyzed metagenomic data from 1500+ patients across five clinical trials, identifying key microbial biomarkers for colorectal cancer (CRC) using differential abundance testing and machine learning methods.
  • Created vectorized scripts in Python, Bash, and R to clean, normalize, and augment datasets for training simple and deep learning classification models, ensuring scalability for large-scale data processing.
  • Utilized ggplot2, Matplotlib, and Seaborn to visualize complex genomic and transcriptomic data, effectively communicating findings in disease and immunity contexts.
  • Implemented novel clustering algorithms on proteomic datasets, categorizing proteins into functional groups based on sequence and 3D structural similarity leading to novel discovery of protein subgroups.
Sep 2023 - Nov 2024

Masters Research Associate

Toronto, Ontario, Canada

  • Applied single-cell RNA sequencing with industry-standard tools Seurat and Cell Ranger to analyze transcriptional responses in small intestinal epithelial cells, managing complex genomic datasets to extract biological.
  • Conducted differential gene expression analysis in epithelial cells under various microbial conditions using R and DESeq2, identifying key genes and pathways affected by microbial interactions.
  • Performed trajectory inference with partition-based graph abstraction (PAGA) and RNA velocity using Monocle and velocyto, interpreting dynamic cellular changes to understand cellular differentiation pathways.
May 2022 - Aug 2023

Summer Research Intern

Toronto, Ontario, Canada

  • Conducted RNA scope and bulk RNA-seq for comprehensive gene expression analysis, revealing critical pathways activated during colitis and stem cell induction, developed a time-course for gut epithelial restitution.
  • Developed a cell profile pipeline to automate the process of quantifying transcripts identified by RNA-scope.
  • Created robust scripts in R for statistical analysis and data visualization, ensuring reproducibility and efficiency.
May 2021 - Sep 2021
Team & coworkers

Colleagues at Ontario Institute for Cancer Research

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2 education records

Oliver De Sa education

Master Of Science - Ms, Immunology

Activities and Societies: Philpott LabUsing bioinformatic methods to ivestigate the role of host-microbiota cross-talk in patient response.

FAQ

Frequently asked questions about Oliver De Sa

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What company does Oliver De Sa work for?

Oliver De Sa works for Ontario Institute for Cancer Research.

What is Oliver De Sa's role at Ontario Institute for Cancer Research?

Oliver De Sa is listed as Bioinformatician at Ontario Institute for Cancer Research.

Where is Oliver De Sa based?

Oliver De Sa is based in Toronto, Ontario, Canada while working with Ontario Institute for Cancer Research.

What companies has Oliver De Sa worked for?

Oliver De Sa has worked for Ontario Institute For Cancer Research, University Of Toronto, and The City Canteen.

Who are Oliver De Sa's colleagues at Ontario Institute for Cancer Research?

Oliver De Sa's colleagues at Ontario Institute for Cancer Research include Sam Rich, Teresa Petrocelli, Theresa Zember, Mark Hayes, and Jessica Miller.

How can I contact Oliver De Sa?

You can use AeroLeads to view verified contact signals for Oliver De Sa at Ontario Institute for Cancer Research, including work email, phone, and LinkedIn data when available.

What schools did Oliver De Sa attend?

Oliver De Sa holds Master Of Science - Ms, Immunology from University Of Toronto.

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