Oscar Cabrera

Oscar Cabrera Email and Phone Number

Hands-on Scientist with Expertise in Cell/Gene Therapy. @ Tessera Therapeutics
Oscar Cabrera's Location
Newton, Massachusetts, United States, United States
Oscar Cabrera's Contact Details

Oscar Cabrera work email

Oscar Cabrera personal email

n/a
About Oscar Cabrera

With over 9 years of hands of professional experience in biotech, I've always cultivated a deep understanding of knowing what new technologies are available and how I can leverage those tools to help patients in the clinic.

Oscar Cabrera's Current Company Details
Tessera Therapeutics

Tessera Therapeutics

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Hands-on Scientist with Expertise in Cell/Gene Therapy.
Oscar Cabrera Work Experience Details
  • Tessera Therapeutics
    Senior Scientist
    Tessera Therapeutics Jun 2022 - Present
    Somerville, Ma, Us
    • Supervised and performed functional studies to generate CAR-T cells (eg. ex vivo and same-day) using Tessera’s gene writer platform (via non-viral gene delivery)• Led cross-functional team efforts with research and CMC to nominate gene writing critical components for potential DC nomination of Tessera’s CAR-T program.• Led a T cell/PBMC cell core operations group of 4 people involved in primary cell banking and donor registration/assessment for suppling frozen cell material across multiple research groups in the organization.
  • Genocea
    Senior Scientist
    Genocea Jun 2021 - May 2022
    • Lead contributor to the current and next generation of ATLAS screening platform, utilizing various techniques including cell sorting, multicolor flow-cytometry, and high-throughput screening assays.• Troubleshot and developed improved workflows applicable for research and clinical development.• Ensured scientific integrity and documentation of experimental data to meet standards suitable for intellectual property and FDA submissions
  • Gsk
    Bench Scientist
    Gsk Jul 2020 - Jun 2021
    Brentford, Middlesex, Gb
    • Key contributor in investigating the biology of novel targets and evaluate the effects of newly developed drug lead candidates in autoimmune disorders (eg. SLE, RA, sarcoidosis).• Designed and performed experiments using cell and molecular techniques suitable for drug target identification and validation.• Generated and presented scientific findings at various meetings to partners/collaborators and collaboratively planned experimental paths moving forward.
  • Genetics Research
    Staff Scientist
    Genetics Research Oct 2019 - Jul 2020
    Wakefield, Massachusetts, Us
    • Key contributor in generating new CRISPR-based assays for enhancing biomarker and early cancer detection discovery using NGS and GR’s Negative Enrichment platform.• Validated target-based enrichment in both genomic and cfDNA using next-gen sequencing and qPCR.• Designed sgRNA and PCR primers / qPCR probes for CRISPR-based targeted enrichment. • Planned and carried out proof-of-concept experiments for developing targeted enrichment kits.
  • Abbvie
    Senior Scientist I
    Abbvie Mar 2018 - Jun 2019
    North Chicago, Illinois, Us
    • Worked cross-functionally with our functional genomics team to screen and validate novel therapeutic targets for the treatment of autoimmune disorders and chronic inflammation.• Supported target validation group by generating CRISPR mutations using both mammalian cell lines and primary immune cells.Managed one associate scientist to develop standard operating procedures (SOPs) for establishing a lentiviral core facility at the AbbVie Cambridge site.• Generated study reports and maintained a detailed record of experiments in electronic lab notebooks in accordance with company policy.
  • Worcester State University
    Adjunct Faculty
    Worcester State University Jan 2016 - May 2018
    Worcester, Ma, Us
    • Prepared and designed course materials such as syllabus, homework assignments and tests• Delivered lectures to undergraduate students on the medical and biological implication of microorganisms such as prokaryotes, eukaryotes and viruses.• Facilitated classroom discussions• Maintained regularly scheduled office hours to advise and assist students.• Courses taught: BI204 – Microbiology (Student Approval Rating – 4.5 on 5 point scale) and BI206 – Medical Microbiology (Student Approval Rating – 3.9 on 5 point scale)
  • University Of Massachusetts Medical School
    Post Doctoral Associate
    University Of Massachusetts Medical School Jan 2015 - Feb 2018
    Worcester, Ma, Us
    • Generated a fluorescent oncogenic Hedgehog reporter cell line to perform a small molecule screen looking for ciliary inhibitors in basal cell carcinoma (a Hedgehog-derived cancer). This work led to the identification of two potential inhibitors that inhibit basal cell carcinoma in a Smo-dependent manner. • Developed an arrayed CRISPR screen using a ciliary Hedgehog reporter cell line to identify novel genes involved in primary cilium-dependent Hedgehog signaling using high-content confocal microscopy. • Advised two junior post-doctoral associates; established multicenter collaboration with other universities for drug screening; supervised the research projects of one graduate rotation student and two undergraduate summer students.
  • Florida State University
    Graduate Research Assistant
    Florida State University Aug 2009 - Dec 2014
    Tallahassee, Fl, Us
    • Developed and executed a proteomic-based approach to identify proteins required for acentrosomal cell division in Drosophila. This work led to the identification of proteins involved oxidative stress, which led us to understand the role for centrosomal proteins involved in cell homeostasis during autophagy.• Executed a forward genetics screen looking for genes required during centrosome loss. This work led to identification of proteins involved in acentrosomal mitosis.
  • University Of Miami,  Miller School Of Medicine
    Undergraduate Research Assistant
    University Of Miami, Miller School Of Medicine Jan 2008 - May 2009
    Miami, Fl, Us
    Project: Studied how methylation of histone H3K56 affects the chromatin remodeling complex SWI/SNF during Nucleotide Excision Repair in Saccharomyces cerevisiae.Responsibilities: Worked under supervision of research associate to isolate chromatin and immunoprecipitate the SWI/SNF complex for H3K56 methylation. Methodologies: Chromatin immunoprecipitation (ChIP), yeast cell culture.
  • University Of Miami,  Miller School Of Medicine
    Work Study Student
    University Of Miami, Miller School Of Medicine Jun 2008 - Sep 2008
    Miami, Fl, Us
    Determined whether gap junction proteins in invertebrates (innexins) form ion channels or receptor through glycosylation.

Oscar Cabrera Education Details

  • Florida State University
    Florida State University
    Biomedical Sciences
  • University Of Miami
    University Of Miami
    Biochemistry And Molecular Biology
  • Harvard Medical School
    Harvard Medical School
    Other; Hmx Fundamentals/Pro Online Certificate Program – Immunology

Frequently Asked Questions about Oscar Cabrera

What company does Oscar Cabrera work for?

Oscar Cabrera works for Tessera Therapeutics

What is Oscar Cabrera's role at the current company?

Oscar Cabrera's current role is Hands-on Scientist with Expertise in Cell/Gene Therapy..

What is Oscar Cabrera's email address?

Oscar Cabrera's email address is os****@****cea.com

What is Oscar Cabrera's direct phone number?

Oscar Cabrera's direct phone number is +178621*****

What schools did Oscar Cabrera attend?

Oscar Cabrera attended Florida State University, University Of Miami, Harvard Medical School.

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