As a Research & Development Scientist, I played a pivotal role as the primary contributor in transformative projects aimed at advancing DNA sequencing technology to achieve unparalleled accuracy. My contributions encompassed a diverse range of responsibilities and accomplishments:-Pioneered cutting-edge surface coatings, bioconjugation chemistry strategies, and nanofabrication techniques crucial for enhancing a DNA sequencing platform's performance and precision.-Spearheaded initiatives in New Product Introduction (NPI), orchestrating the development and validation of processes for consumable surfaces to ensure optimal functionality and reliability.-Contributed significantly to the advancement of short-read sequencing technologies, contributing to breakthroughs in sequencing efficiency and data accuracy.-Introduced the principles of Design of Experiments (DOE) to streamline experimentation processes, optimize workflows, and drive continuous improvement in product development.-Established and transferred robust Quality Control (QC) methods, ensuring meticulous tracking of finished consumable quality across NPI and Manufacturing Departments.-Developed innovative QC methodologies to evaluate the quality of various manufacturing process steps, enhancing overall product quality and reliability.-Presented comprehensive data analyses, project updates, and strategic insights to external departments and upper management, fostering collaboration and aligning project goals with organizational objectives.-Took the lead in the development of flow cells tailored for DNA sequencing platforms, leveraging Agile methodologies and lean six sigma principles to drive efficiency, minimize waste, and accelerate project timelines.This multifaceted experience reflects my expertise in research and development, project management, quality assurance, and strategic decision-making within the biotechnology and life sciences industries.

Focused on leveraging DNA-assisted self-assembly techniques to engineer innovative nanostructures. Specifically, I synthesized quantum dot semiconductors and utilized DNA scaffolds to construct intricate 2D and 3D architectures. These structures were designed for various applications, including the development of DNA biosensors with enhanced sensitivity and specificity, DNA Microarrays and microfluidic devices for molecular diagnosis and next-generation sequencing.Additionally, engineered gold-coated iron oxide superparamagnetic nanoparticles, harnessing their unique properties for energy transfer and magneto-plasmonic studies. This interdisciplinary approach integrated aspects of surface chemistry, nanomaterials synthesis, and DNA nanotechnology to create novel hybrid materials.Skills Demonstrated:-DNA-assisted self-assembly-Quantum dot synthesis and characterization-DNA biosensor development-Surface chemistry for nanoparticle functionalization-Energy transfer studies-Nanomaterials synthesis and characterization (SEM, TEM, AFM, EDX, XPS)-DNA data storage concepts-Advanced spectroscopic techniques (UV-Vis, FTIR, NMR, fluorescence spectroscopy)-Gel electrophoresis and SDS-PAGE for biomolecular analysisThis project not only showcased my expertise in nanoscience and bioconjugation but also highlighted my proficiency in a diverse range of characterization techniques essential for cutting-edge research in physical chemistry and nanotechnology.

Focused on establishing molecular analogues tailored for enzymatic NADH/NAD+ hydride transfer reactions. This involved intricate organic synthesis techniques to design and synthesize analogues mimicking key aspects of the NADH/NAD+ system. Leveraging the hydrogen tunneling mechanism, I aimed to better characterize enzyme targets crucial for drug discovery efforts.I conducted comprehensive kinetic measurements, including primary and secondary kinetic isotope effects, to gain deeper insights into the enzymatic processes. This approach not only provided a refined understanding of enzyme kinetics but also facilitated the identification of potential drug targets.Additionally, I utilized advanced spectroscopic techniques such as NMR spectroscopy to elucidate the structural and dynamic properties of the synthesized analogues. This enabled precise characterization and validation of the molecular models, further enhancing our understanding of enzyme-substrate interactions.Skills Demonstrated:-Organic synthesis for molecular analogue design-NMR spectroscopy for structural elucidation-Enzymatic kinetic measurements-Hydrogen tunneling mechanism studies-Spectroscopic techniques (UV-Vis, FTIR) for compound analysis-Kinetic isotope effect analysis-Molecular modeling and simulation This project underscored my proficiency in organic synthesis, NMR spectroscopy, and enzymology, showcasing a multidisciplinary approach to advance drug discovery efforts through mechanistic studies and targeted analogue design.

Experienced in structure-based drug discovery for Mycobacterium Tuberculosis targets, adept in a range of molecular biology techniques including molecular cloning, DNA Extraction, PCR, gene expression, protein expression, and protein purification. Skilled in characterizing proteins using SEC, IEC, LC-MS, FPLC, and gel electrophoresis, ensuring rigorous quality control and precise analysis.

Collaborated with colleagues in both domestic and international support facilities. Evaluated and responded to incoming sales leads and requests for technical support assistance.